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Southeast Missouri Two Star Hotels from RM252

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Check availability on Southeast Missouri 2 Star Hotels

Tonight
28 Sept - 29 Sept
Tomorrow
29 Sept - 30 Sept
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Southeast Missouri 2-star hotels

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

1. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Elizabeth
RM293
RM331 total
includes taxes & fees
4 Oct - 5 Oct
Pear Tree Inn Cape Girardeau West
A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A hotel room with a large bed, two sofas, a desk with a lamp, a microwave, and a TV.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.
A gym with cardio equipment, a bench press, and a squat rack.

2. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
United States
ILUNGA
RM231
RM252 total
includes taxes & fees
25 Oct - 26 Oct
Baymont Inn and Suites by Wyndham Farmington, MO
A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.
A hotel lobby with a reception desk, two red armchairs, a coffee table, a floral centerpiece, and a dining area with wooden tables and chairs.
A hotel room with a shower, a bathtub, a toilet, a bed, a desk, a chair, and a television.
A hotel room with a living area, kitchenette, and a desk with a computer and chair.

3. Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
Festus
United States
Michelle
RM290
RM339 total
includes taxes & fees
25 Oct - 26 Oct
Comfort Inn Festus - St Louis South
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

4. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
David
RM270
RM308 total
includes taxes & fees
30 Sept - 1 Oct
Days Inn and Suites by Wyndham Sikeston
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

5. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Rhonda
RM357
RM400 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Poplar Bluff
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A motel with a prominent '66' sign, large windows, and a flat roof.
A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

6. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Cindy
RM301
RM338 total
includes taxes & fees
29 Sept - 30 Sept
Motel 6 Poplar Bluff, MO
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.
A motel with a covered entrance, multiple rooms, and a parking lot.
A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

7. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
United States
William
RM233
RM265 total
includes taxes & fees
25 Oct - 26 Oct
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.
A buffet with various food items, including omelets and other dishes, served in metal containers with glass lids.
A swimming pool with a diving board, pool rules signs, and lounge chairs.
A kitchen counter with a coffee machine, a kettle, and storage boxes.

8. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville
United States
David
RM428
RM490 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express & Suites Perryville by IHG
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

9. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
RM411
RM468 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A modern kitchen with a central island, built-in appliances, and a view into the dining area.
A modern hotel with a stone facade, multiple windows, outdoor seating, and a visible sign for the Holiday Inn Express & Suites.
A hotel room with a bed, a desk, a microwave, a coffee maker, and a TV mounted on the wall.
A reception desk with a modern design, a digital screen, and a sign indicating 'IHG' branding.

10. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Festus
United States
Steven
RM448
RM512 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

11. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Shelley
RM352
RM401 total
includes taxes & fees
29 Oct - 30 Oct
Best Western Plus Sikeston I-55
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.
A spacious hotel lobby with a dining area, kitchen, and large windows.
A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

12. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
Farmington
United States
Susan
RM447
RM486 total
includes taxes & fees
14 Oct - 15 Oct
Crown Pointe Lodge, BW Signature Collection
A hotel room with two beds, a TV, a desk, and a wardrobe.
A spacious lobby with a reception desk, a chandelier, and a large window.
A building with a sign that reads "The Farmstead."
A reception desk with a sign reading "The FARMSTEAD," a vending machine with snacks, and a water cooler.

13. The Farmstead Hotel

The Farmstead Hotel
Caruthersville
United States
Alex
RM387
RM440 total
includes taxes & fees
29 Sept - 30 Sept
The Farmstead Hotel
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel patio with a gazebo, outdoor seating, and a view of the road.

14. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
RM346
RM413 total
includes taxes & fees
11 Oct - 12 Oct
Candlewood Suites Cape Girardeau by IHG
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

15. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
John
RM414
RM469 total
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn Sikeston
A living room with a sofa, coffee table, and a small table with a vase. There is a window with blinds and a door in the background.
An indoor swimming pool with a 3 FT depth marker, surrounded by white walls and a ceiling with recessed lighting.
A reception area with a green marble counter, framed certificates on the wall, and a clock.
A hotel room with a bed, a desk, a chair, a couch, and a TV.

16. Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
Bonne Terre
United States
Elizabeth
RM265
RM290 total
includes taxes & fees
4 Oct - 5 Oct
Super 8 by Wyndham Bonne Terre
A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.
A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.
A hotel lobby with a coffee station, seating area, and a television screen.
A hotel with a covered entrance, multiple windows, and a yellow facade.

17. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
Poplar Bluff
United States
Muhammad
RM329
RM372 total
includes taxes & fees
18 Oct - 19 Oct
Comfort Inn Poplar Bluff North
A modern retail area with a display of local items and snacks.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

18. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Shannon
RM364
RM414 total
includes taxes & fees
4 Oct - 5 Oct
Tru By Hilton Cape Girardeau
A hotel room with a large bed, two bedside tables, a nightstand, and a framed picture on the wall.
A hotel reception area with a green carpet, a reception desk, a seating area with chairs, and a poster advertising the hotel.
An indoor swimming pool with clear lanes, a sunlit room with a view, and a staircase leading to an upper level.
A modern kitchen with granite countertops, wooden chairs, and a dining table. There are various food items and a sign indicating hot beverages.

19. Quality Inn Farmington

Quality Inn Farmington
Farmington
United States
Desiree
RM225
RM258 total
includes taxes & fees
25 Oct - 26 Oct
Quality Inn Farmington
A modern kitchen with a coffee machine, a refrigerator, and a microwave.
A hotel lobby with a reception desk, a blue armchair, a wall-mounted clock, and a framed welcome sign.
A hotel room with a large bed, a smaller bed, a nightstand with a lamp, and two large framed pictures on the wall.
A long, narrow hallway with patterned carpet, doors on both sides, and a ceiling light.

20. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington
United States
Marisa
RM242
RM264 total
includes taxes & fees
11 Oct - 12 Oct
Super 8 by Wyndham Farmington
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Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Southeast Missouri.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO
RM407
RM460 total
4 Oct - 5 Oct
includes taxes & fees
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO
RM383
RM440 total
4 Oct - 5 Oct
includes taxes & fees
9.6/10 Exceptional! (1,002 reviews)
Drury Inn & Suites Sikeston, MO
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3003 SOUTH OLD ORCHARD ROAD Jackson MO
RM343
RM371 total
29 Sept - 30 Sept
includes taxes & fees
9/10 Wonderful! (859 reviews)
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri
A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"I loved everything about this cabin and I was on a high from this experience."
Paris 1-night trip
Posted 2 days ago
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

8/10 Good
"Definitely worth it, clean"
Joy 1-night trip
Posted 3 days ago
Motel 6 Poplar Bluff, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"This was a very good value. It has been the best hotel I've stayed at in awhile."
David 1-night trip
Posted 7 days ago
Days Inn and Suites by Wyndham Sikeston

Find out more about Southeast Missouri

Find Your Ideal 2 Star Hotels in Southeast Missouri

When you've got to get away to a new or favourite destination without breaking the bank, Southeast Missouri awaits with top 2 star hotels and a change of scenery. Stay on your feet visiting top attractions that draw several of visitors, or settle in for a hot cuppa nearby and enjoy some R & R. You're about to find out why locals and travellers alike love this place. Pack your bags and get ready for new experiences and a relaxing stay in a city with strong overall 2 star hotels ratings. Guest reviews recommend their 2 star hotels in Southeast Missouri, and it's time to find out why.

The Ideal Hotel at the Perfect Price

Motels are in high demand in Southeast Missouri. You'll find the best deals right here, so book early and save on a great getaway. Thanks to budget-friendly prices and traveller-friendly amenities, past travellers have found an accommodation that's just right. Browse guest reviews to find out what they loved, liked, and can't wait to try again. The best travel is all about hospitality, and these motels have a strong service, these rooms are tidy and cosy. When you book with Expedia, you can stay all over the world, and the journey starts in Southeast Missouri.

Reserve a Stay in a Two-Star Hotel Today!

Book your stay in this popular place today -- Southeast Missouri is a destination on the rise. It's no secret that Southeast Missouri is a great place to stay, so get the best deals while you can, and get to know exactly what everyone loves about Southeast Missouri. Your home away from home is waiting. Book the best deals on 2-star hotels and motels in Southeast Missouri now.

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