Photo by Ryan Coleman

Independent Sikeston hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Our top choices for Sikeston Independent

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (480)
" Excellent stay. Will come again"
United States
joydeep
The price is RM390
RM440 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Riverview

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (725)
"Clean room and easy access to room"
United States
Anne
The price is RM225
RM256 total
includes taxes & fees
8 Jan - 9 Jan 2026
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (333)
"Room was nice and spacious."
United States
Rebecca
The price is RM273
RM307 total
includes taxes & fees
14 Jan - 15 Jan 2026
Dexter Inn

Hotel 7 Inn Anna

Hotel 7 Inn Anna
2.5 star property
Anna
6.6 out of 10, (217)
"The staff was wonderful"
United States
Donna
The price is RM323
RM375 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel 7 Inn Anna

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is RM223
RM260 total
includes taxes & fees
5 Jan - 6 Jan 2026
Town House Inn Cape Giradreau

Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (426)
"The staff member Tim was very friendly and nice. "
United States
Julie
The price is RM262
RM284 total
includes taxes & fees
29 Jan - 30 Jan 2026
Town House Inn

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (121)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is RM217
RM258 total
includes taxes & fees
1 Jan - 2 Jan 2026
Country Yard Inn and Suite

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (84)
"Cute room, great food, fun soda fountain and friendly owners! Will return! "
United States
Leslie
EC Reed's Mercantile and Hotel

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (19)
"My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! "
United States
Kim
The price is RM669
RM755 total
includes taxes & fees
12 Jan - 13 Jan 2026
Rockwood Inn

Davie School Inn

Davie School Inn
4.0 star property
Anna
10.0 out of 10, Exceptional, (51)
"very friendly hosts, great bfasts, excellent stay!"
United States
Rebecca
Davie School Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Sikeston Hotel Reviews