Southeast Missouri

Travel Guide

Southeast Missouri
Southeast Missouri
Southeast Missouri
Photo by Jessica Richter
Photo by Jessica Richter
Photo by Jessica Richter
Photo by Jessica Richter
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
The price is RM237 per night from 12 Aug to 13 Aug
RM237
RM270 total
12 Aug - 13 Aug
includes taxes & fees
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,001 reviews)
"Fair prices and nice staff well taken care ofby the Baymont family"

Reviewed on 30 Jul 2025

Baymont Inn and Suites by Wyndham Farmington, MO
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is RM446 per night from 31 Jul to 1 Aug
RM446
RM503 total
31 Jul - 1 Aug
includes taxes & fees
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront Park are ...
9.2/10 Wonderful! (364 reviews)
"Beautiful spacious room."

Reviewed on 27 Jul 2025

The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
The price is RM381 per night from 7 Aug to 8 Aug
RM381
RM429 total
7 Aug - 8 Aug
includes taxes & fees
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,016 reviews)
5 stars
"Hotel was extremely nice and comfortable. Unfortunately my family was unable to take advantage of the drinks and snacks in the lobby due to several youth volleyball teams also staying at the hotel. They took over the lobby and pool area and were so loud we couldn’t hear the hotel staff checking us ..."

Reviewed on 24 Jul 2025

Drury Plaza Hotel Cape Girardeau Conference Center
See all 588 properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
9.4/10 Exceptional! (148 reviews)
"This is my 3rd time staying here and second time as a family. and every time Ive stayed it has been clean and pleasant. Only a couple run ins with a spider and a wasp. Beyond that we have nothing to complain about and loved the bath!! We will be back again."

Reviewed on 14 Jul 2025

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Postcard Cabins St. Francois

Postcard Cabins St. Francois

2 out of 5
7555 State Hwy Y, French Village, MO
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
10/10 Exceptional! (22 reviews)
"Even with the summer heat, don’t pass up on this opportunity. If you want something quiet, relaxing, and to just generally get away from the noise of life, give this place a weekend of your time and get exactly that in return."

Reviewed on 28 Jul 2025

Postcard Cabins St. Francois
Sam A Baker State Park

Sam A Baker State Park

2 out of 5
5732 State Hwy Missouri 143, Patterson, MO
Stay at this cabin in Patterson. Enjoy free parking, a picnic area, and furnished patios. Popular attraction Sam A. Baker State Park is located nearby.
Sam A Baker State Park
See all properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Elephant Rocks State Park

Elephant Rocks State Park

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

Elephant Rocks State Park
Echo Bluff State Park

Echo Bluff State Park

5/5(1 review)

You can take time to visit Echo Bluff State Park during your travels to Salem. While you're in the area, stroll along the riverfront.

Echo Bluff State Park
Rocky Falls

Rocky Falls

Commune with nature and explore the great outdoors at Rocky Falls during your travels in Winona. While you're in the area, wander around the natural setting.

Rocky Falls
Lake Wappapello

Lake Wappapello

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

Lake Wappapello

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.

Southeast Missouri State University

Century Casino Caruthersville

Why not try your luck with a visit to Century Casino Caruthersville during your visit to Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

Century Casino Caruthersville

Things to do

Castle Entrance

History Tour of Pythian Castle in Springfield Missouri

RM53
per adult
90% of travellers recommend
History Tour of Pythian Castle in Springfield Missouri
Ozark Craft Beverage - Brewery Tour

Ozark Craft Beverage - Brewery Tour

RM436
per adult
Ozark Craft Beverage - Brewery Tour
See all activities in Southeast Missouri
Photo by Summer Williams

Fredericktown

Photo by Jennifer Radman

Park Hills

Photo by Ryan Coleman

Sikeston