Photo by Bill Dillard

Southeast Missouri hotels from RM238
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Family friendly
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Check prices for these dates
Our top choices for Southeast Missouri hotels

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (61 reviews)
The price is RM391
RM591 total
includes taxes & fees
23 Apr - 24 Apr

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (176 reviews)
The price is RM366
RM413 total
includes taxes & fees
3 May - 4 May

Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (346 reviews)
The price is RM377
RM409 total
includes taxes & fees
27 Apr - 28 Apr

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,004 reviews)
The price is RM324
RM343 total
includes taxes & fees
17 May - 18 May

Lake Wappapello
Lake WappapelloWilliamsville
10.0 out of 10, Exceptional, (2 reviews)
The price is RM336
RM354 total
includes taxes & fees
28 Apr - 29 Apr

Echo Bluff State Park
Echo Bluff State ParkEminence
9.6 out of 10, Exceptional, (241 reviews)
The price is RM727
RM769 total
includes taxes & fees
22 Apr - 23 Apr

Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
8.0 out of 10, Very good, (1,010 reviews)
The price is RM237
RM258 total
includes taxes & fees
7 May - 8 May

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (121 reviews)
The price is RM386
RM439 total
includes taxes & fees
28 Apr - 29 Apr

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (752 reviews)
The price is RM352
RM381 total
includes taxes & fees
22 Apr - 23 Apr

Current River Inn
Current River InnVan Buren
8.2 out of 10, Very good, (170 reviews)
The price is RM430
RM466 total
includes taxes & fees
22 Apr - 23 Apr

New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very good, (757 reviews)
The price is RM224
RM242 total
includes taxes & fees
26 Apr - 27 Apr

The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (540 reviews)
The price is RM375
RM427 total
includes taxes & fees
30 Apr - 1 May

Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.2 out of 10, Wonderful, (310 reviews)
The price is RM427
RM466 total
includes taxes & fees
26 Apr - 27 Apr

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,004 reviews)
The price is RM403
RM464 total
includes taxes & fees
29 Apr - 30 Apr

EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
9.6 out of 10, Exceptional, (86 reviews)
The price is RM369
RM402 total
includes taxes & fees
23 Apr - 24 Apr

Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
8.4 out of 10, Very good, (983 reviews)
The price is RM262
RM300 total
includes taxes & fees
10 May - 11 May

Arcadia Academy
Arcadia AcademyArcadia
9.8 out of 10, Exceptional, (12 reviews)
The price is RM538
RM584 total
includes taxes & fees
4 May - 5 May

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (767 reviews)
The price is RM259
RM295 total
includes taxes & fees
22 Apr - 23 Apr

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (552 reviews)
The price is RM523
RM590 total
includes taxes & fees
30 Apr - 1 May

Hampton Inn By Hilton Dexter
Hampton Inn By Hilton DexterDexter
10.0 out of 10, Exceptional, (20 reviews)
The price is RM433
RM486 total
includes taxes & fees
26 Apr - 27 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (61 reviews)
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Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
8/10 Good
More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is RM237 per night from 7 May to 8 May
RM237
RM258 total
7 May - 8 May
includes taxes & fees
8/10 Very Good! (1,010 reviews)

4 Star Hotels
2 properties
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