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Southeast Missouri hotels from RM228
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Our top choices for Southeast Missouri hotels

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,009 reviews)
The price is RM365
RM412 total
includes taxes & fees
22 Jan - 23 Jan

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,003 reviews)
The price is RM337
RM356 total
includes taxes & fees
19 Jan - 20 Jan

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (50 reviews)
The price is RM410
RM464 total
includes taxes & fees
24 Jan - 25 Jan

The Farmstead Hotel
The Farmstead HotelCaruthersville
8.8 out of 10, Excellent, (473 reviews)
The price is RM308
RM351 total
includes taxes & fees
30 Jan - 31 Jan

Echo Bluff State Park
Echo Bluff State ParkEminence
9.4 out of 10, Exceptional, (219 reviews)
The price is RM666
RM704 total
includes taxes & fees
19 Jan - 20 Jan

Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.2 out of 10, Wonderful, (982 reviews)
The price is RM426
RM481 total
includes taxes & fees
6 Feb - 7 Feb

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (491 reviews)
The price is RM391
RM441 total
includes taxes & fees
19 Jan - 20 Jan

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (105 reviews)
The price is RM363
RM413 total
includes taxes & fees
27 Jan - 28 Jan

Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHGPoplar Bluff
8.8 out of 10, Excellent, (714 reviews)
The price is RM446
RM504 total
includes taxes & fees
24 Jan - 25 Jan

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
The price is RM284
RM323 total
includes taxes & fees
22 Jan - 23 Jan

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
7.8 out of 10, Good, (1,001 reviews)
The price is RM231
RM244 total
includes taxes & fees
20 Jan - 21 Jan

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,004 reviews)
The price is RM381
RM439 total
includes taxes & fees
21 Jan - 22 Jan

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (151 reviews)
The price is RM357
RM403 total
includes taxes & fees
25 Jan - 26 Jan

Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (551 reviews)
The price is RM369
RM423 total
includes taxes & fees
25 Jan - 26 Jan

Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (336 reviews)
The price is RM365
RM396 total
includes taxes & fees
25 Jan - 26 Jan

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (463 reviews)
The price is RM415
RM469 total
includes taxes & fees
1 Feb - 2 Feb

Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very good, (43 reviews)
The price is RM226
RM259 total
includes taxes & fees
19 Jan - 20 Jan

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (866 reviews)
The price is RM421
RM475 total
includes taxes & fees
31 Jan - 1 Feb

Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (798 reviews)
The price is RM440
RM492 total
includes taxes & fees
14 Feb - 15 Feb

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (480 reviews)
The price is RM507
RM575 total
includes taxes & fees
1 Feb - 2 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:30 Jan - 1 Feb
Image gallery for Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
9.4/10Exceptional (866 reviews)
15% off
Price is RM433
RM978 total
includes taxes & fees
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Stay near popular Central United States attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.

Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
More cheap stays in Southeast Missouri

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
The price is RM231 per night from 17 Feb to 18 Feb
RM231
RM244 total
17 Feb - 18 Feb
includes taxes & fees
7.8/10 Good! (1,005 reviews)

4 Star Hotels
2 properties
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