Travel to Southeast Missouri

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Top hotels in Southeast Missouri

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is RM308 per night from 26 May to 27 May
RM308
per night
26 May - 27 May
8.8/10 Excellent! (1,001 reviews)
"We never heard another person. Staff was wonderful."

Reviewed on 12 May 2024

Pear Tree Inn Cape Girardeau West
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is RM317 per night from 28 May to 29 May
RM317
per night
28 May - 29 May
8.6/10 Excellent! (1,003 reviews)
"18 years ago, my wife and I stayed in the honeymoon suite and it was wonderful. This time, we had the opportunity to stay there with our son and it was wonderful. The staff was very friendly and immediately took care of getting us checked-in so that we could make in time for our niece’s graduation. ..."

Reviewed on 13 May 2024

Auburn Place Hotel And Suites
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is RM323 per night from 27 May to 28 May
RM323
per night
27 May - 28 May
7/10 Good! (1,001 reviews)
"Quiet, easy access, great bed, clean rooms"

Reviewed on 13 May 2024

Days Inn and Suites by Wyndham Sikeston
See all 568 properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Southeast Missouri holiday package cost?
Cross off another part of the world with our Southeast Missouri holiday packages, which start from just . Select the flights and hotels that match your travel plans. Then, add on one or two tours or experiences for an unforgettable adventure.
How do I get a cheap travel package to Southeast Missouri?
Browse and book everything in the one place with our Southeast Missouri holiday packages. You’ll find deals on flights, hotels, tours and more that’ll keep your pocket happy and your adventurous spirit alive. And, with more than 550 partner airlines and 1,000,000 hotels around the world to select from, you’ll have endless opportunities to mix and match your own way.
What are the top hotels in Southeast Missouri?
When it comes to properties in Cape Girardeau, Drury Plaza Hotel Cape Girardeau Conference Centre and Pear Tree Inn Cape Girardeau West are a couple of favourites. If you’re considering heading to Ste Genevieve, City Place St. Louis Downtown and The Branson Hillside Hotel are waiting to welcome you.
How far in advance should I book my Southeast Missouri holiday?
It’s tricky picking the perfect time for airfares, but we generally say the earlier, the better. Many international journeys on Expedia become available up to a year in advance. If you can’t book ahead, don’t worry. Cheap prices appear from time to time within a few weeks of departure dates.
What does an Expedia Southeast Missouri travel package include?
From hotels and flights to car rentals, Expedia can help you craft a Southeast Missouri package that fits you. Holidaying for a week or two? Look into a rental car, hotel and flight bundle. If you’re taking a quick break, a hotel and airfare deal may suit you better. Experiences can also be added once you’ve made your booking. Our packages make it a breeze to plan and save.
What should I know before booking a Southeast Missouri travel package?
When you book your flights, hotels and car rentals together, you’ll pick up terrific discounts. Whether you’re planning a beach escape in a villa or prefer to stay in a comfortable hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Southeast Missouri Expedia holiday package?
You can, and with over 550 airlines to pick from around the world, you’re spoiled for choice. Have a look through the available options and see which airline best suits your budget and needs.
If I'm not able to travel, can I cancel my Southeast Missouri holiday package?
Because we understand life is full of surprises, the answer is yes. To learn more, head to our Customer Service Portal. But generally speaking, if you’ve booked your Southeast Missouri holiday package in the last 24 hours, you may be able to cancel or change it for no charge. Your hotel, airline or car rental company may charge a fee if your booking is older than that.

Popular places to visit

Image for Meramec Caverns

Meramec Caverns

Explore the great outdoors at Meramec Caverns, a lovely green space in Sullivan. While in this family-friendly area, you can enjoy the cafes.

Meramec Caverns
Image for Elephant Rocks State Park

Elephant Rocks State Park

Explore the great outdoors at Elephant Rocks State Park, a lovely green space in Ironton. Make some time to visit the shops while you're in the area.

Elephant Rocks State Park
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Ohio River

Commune with nature and explore the great outdoors at Ohio River during your travels in Valley Station. While you're in the area, wander around the parks.

Ohio River

What to do in Southeast Missouri

Image for Night Ghost Tour of Pythian Castle in Springfield Missouri

Night Ghost Tour of Pythian Castle in Springfield Missouri

RM93
Per adult
100% of travellers recommend
Night Ghost Tour of Pythian Castle in Springfield Missouri
Image for History Tour of Pythian Castle in Springfield Missouri

History Tour of Pythian Castle in Springfield Missouri

RM58
Per adult
80% of travellers recommend
History Tour of Pythian Castle in Springfield Missouri
Image for Ozark Craft Beverage - Brewery Tour

Ozark Craft Beverage - Brewery Tour

RM478
Per adult
Ozark Craft Beverage - Brewery Tour
See all activities in Southeast Missouri

More trip options

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.