Southeast Missouri Spa Hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Southeast Missouri Hotels with Spa
Top Southeast Missouri Hotels with Spa

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1002)
The price is RM382
RM439 total
includes taxes & fees
13 Jul - 14 Jul

Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti Caruthersville
9.4 out of 10, Exceptional, (1001)
The price is RM399
RM454 total
includes taxes & fees
18 Jul - 19 Jul

Super 8 by Wyndham Perryville
Super 8 by Wyndham Perryville
8.4 out of 10, Very good, (875)
The price is RM288
RM330 total
includes taxes & fees
16 Jul - 17 Jul

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
9.6 out of 10, Exceptional, (722)
The price is RM465
RM525 total
includes taxes & fees
20 Jul - 21 Jul

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
9.6 out of 10, Exceptional, (1004)
The price is RM382
RM403 total
includes taxes & fees
21 Jul - 22 Jul

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
9.0 out of 10, Wonderful, (1000)
The price is RM305
RM344 total
includes taxes & fees
15 Jul - 16 Jul

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
9.4 out of 10, Exceptional, (955)
The price is RM382
RM430 total
includes taxes & fees
15 Jul - 16 Jul

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
8.4 out of 10, Very good, (661)
The price is RM299
RM341 total
includes taxes & fees
11 Jul - 12 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Reviews in Southeast Missouri
Recent Reviews in Southeast Missouri

Drury Plaza Hotel Cape Girardeau Conference Center
5/5 Excellent
"Clean, large rooms and a comfortable bed.
Arrived just as taco dinner & drinks were being served. Which was great after a long day of traveling."
A verified traveller stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted 3 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
More Hotel Options in Southeast Missouri
- Budget Hotels in Southeast Missouri
- Business Hotels in Southeast Missouri
- Family friendly Hotels in Southeast Missouri
- Hotels with Air Conditioning in Southeast Missouri
- Hotels with Balcony in Southeast Missouri
- Hotels with Bars / Lounges in Southeast Missouri
- Hotels with Breakfast in Southeast Missouri
- Hotels with Entertainment in Southeast Missouri
- Hotels with Gyms in Southeast Missouri
- Hotels with Hot Tubs in Southeast Missouri
- Hotels with Internet in Southeast Missouri
- Hotels with Restaurants in Southeast Missouri
- Hotels with Swimming Pools in Southeast Missouri
- Hotels with Views in Southeast Missouri
- Hotels with connecting rooms in Southeast Missouri
- Hotels with free Internet in Southeast Missouri
- Hotels with free breakfast in Southeast Missouri
- Hotels with free parking in Southeast Missouri
- Hotels with free wifi in Southeast Missouri
- Hotels with indoor pool in Southeast Missouri
- Hotels with kitchenette in Southeast Missouri
- Hotels with parking in Southeast Missouri
- Hotels with shuttle in Southeast Missouri
- Hotels with smoking rooms in Southeast Missouri
- Luxury Hotels in Southeast Missouri
- Pet friendly Hotels in Southeast Missouri
- Romantic Hotels in Southeast Missouri
More Accommodation Types in Southeast Missouri
- Apartments in Missouri
- Condo Rentals in Missouri
- Cottages in Missouri
- Private Holiday Homes in Missouri
- Motels in Missouri
- Cabin Rentals in Missouri
- B&B in Missouri
- Aparthotels in Missouri
- Guest Houses in Missouri
- Lodges in Missouri
- Resorts in Missouri
- Villas in Missouri
- Inns in Missouri
- Caravan Parks in Missouri
- Town Houses in Missouri
- Condominium Resorts in Missouri
- Chalets in Missouri
- Hostels in Missouri
- Residences in Missouri