A sunset over a mountainous landscape with scattered clouds.

Best Luxury Hotels in La Mesa

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Check availability on La Mesa Luxury Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for La Mesa luxury hotels

A luxurious room with a grand piano, plush blue sofas, ornate chandeliers, and elegant decor.

1. Westgate Hotel

Westgate Hotel
4.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,066 reviews)
  • cleanliness
    Indulge in upscale pampering at this city centre San Diego hotel featuring a rooftop pool, full-service spa, and elegant accommodation.
The price is RM622
RM863 total
includes taxes & fees
16 Nov - 17 Nov
Westgate Hotel
A hotel lobby with a modern chandelier, comfortable seating, a large window with a mountain view, and a television screen.

2. Jamul Casino Resort

Jamul Casino Resort
4.5 star property
Otay Ranch
9.4 out of 10, Exceptional, (25 reviews)
The price is RM773
RM852 total
includes taxes & fees
2 Nov - 3 Nov
Jamul Casino Resort
A multi-story hotel with a modern design, featuring a central courtyard with palm trees and a well-lit entrance.

3. Viejas Casino & Willows Hotel

Viejas Casino & Willows Hotel
4.0 star property
Alpine
9.2 out of 10, Wonderful, (1,074 reviews)
  • cleanliness
    Alpine casino resort offers luxury pillowtop beds, full-service spa with couples treatments, and poolside relaxation.
The price is RM548
RM678 total
includes taxes & fees
3 Nov - 4 Nov
Viejas Casino & Willows Hotel
A spacious dining area with high ceilings, large chandeliers, and a modern interior design.

4. Pendry San Diego

Pendry San Diego
5.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    City centre luxury experience with a full-service spa, outdoor pool, and three on-site restaurants to elevate your San Diego stay.
The price is RM1,206
RM1,623 total
includes taxes & fees
22 Nov - 23 Nov
Pendry San Diego
Two beach chairs with 'The Bower Coronado' branding, a beach umbrella, and a bucket with a bottle of champagne on a sandy beach with ocean waves in the background.

5. The Bower Coronado

The Bower Coronado
5.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (346 reviews)
  • cleanliness
    Coronado beach luxury with ocean-view dining and exclusive concierge service awaits.
The price is RM1,026
RM1,356 total
includes taxes & fees
29 Oct - 30 Oct
The Bower Coronado
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

6. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (236 reviews)
  • cleanliness
    Luxury retreat with rooftop terrace offers champagne service near San Diego Bay.
The price is RM488
RM689 total
includes taxes & fees
2 Nov - 3 Nov
City24 Hotel Little Italy Mission Hills
A large, historic hotel with multiple floors, a central courtyard, and a prominent entrance.

7. The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego
5.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Timeless elegance meets urban luxury at this historic hotel, where Beaux Arts charm mingles with exceptional service in city centre San Diego.
The price is RM1,039
RM1,207 total
includes taxes & fees
25 Nov - 26 Nov
The US Grant, a Luxury Collection Hotel, San Diego
A rooftop pool with lounge chairs and a city skyline in the background.

8. Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (556 reviews)
  • cleanliness
    Savour sophistication in this luxury San Diego aparthotel with private balconies, a sauna, hot tub, and outdoor pool steps from city centre.
The price is RM790
RM1,215 total
includes taxes & fees
29 Oct - 30 Oct
Kasa Little Italy San Diego
A courtyard with a stone pathway leading to two wooden cabins with tiled roofs.

9. Rancho Bernardo Inn

Rancho Bernardo Inn
4.0 star property
Rancho Bernardo
8.8 out of 10, Excellent, (1,000 reviews)
The price is RM927
RM1,245 total
includes taxes & fees
25 Nov - 26 Nov
Rancho Bernardo Inn
A resort with a large swimming pool, multiple buildings, and surrounding greenery.

10. Fairmont Grand Del Mar

Fairmont Grand Del Mar
5.0 star property
Carmel Valley
9.4 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Mediterranean luxury meets impeccable service at this 5-star spa resort with championship golf, multiple pools, and elegant dining venues.
The price is RM1,909
RM2,527 total
includes taxes & fees
30 Oct - 31 Oct
Fairmont Grand Del Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

The Sofia Hotel

The Sofia Hotel

10/10 Excellent
"The room and property were great! Clean and friendly staff. Room was small but more than enough for a couple. Close enough to walk to many local bars and restaurants but far enough away from the lively areas to be quiet even with a room looking out directly over Broadway St. We didn't have a car so can't comment on parking. No complaints!"
Jason 5-night trip
Posted less than an hour ago
The Sofia Hotel

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to La Mesa?
Use Expedia and let us help you arrange a flight to San Diego, CA (SEE-Gillespie Field) airport or San Diego, CA (MYF-Montgomery Field) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to get what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that La Mesa has to offer. During your visit, you might want to enjoy the entertainment which La Mesa is known for.
When can I expect good weather in La Mesa?
Planning for the weather is an important factor for making your trip to La Mesa a success, especially when you're splurging. The hottest months are usually August and September, with an average temperature of 22°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for La Mesa is 308 mm.
What's there to see and do in La Mesa?
Enjoy La Mesa with a stop at Mount Helix Park, San Diego Zoo and Mission Bay. If you have a bit of extra time while you're in the area, you might want to check out Petco Park and Port of San Diego.
How can I get around La Mesa?
It's easier to get around town in style when you know your options. Nearby metro stations include La Mesa Boulevard Station, Spring St Trolley Station and 70th St. Trolley Station.

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