Best Luxury Hotels in La Mesa

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on La Mesa Luxury Hotels

Our top choices for La Mesa luxury hotels

Lobby

Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego
2.5 star property
La Mesa
8.4 out of 10, Very good, (1,005 reviews)
"Everyone was inviting and nice."
United States
Andrew
The price is RM461
RM507 total
includes taxes & fees
1 Feb - 2 Feb
Best Western Plus La Mesa San Diego
Blackout curtains, free WiFi, bed sheets

Motel 6 La Mesa, CA

Motel 6 La Mesa, CA
2.0 star property
La Mesa
7.2 out of 10, Good, (1,002 reviews)
"Very nice room. No shampoo but soap was good. Close to hospital."
United States
Betsy
The price is RM324
RM357 total
includes taxes & fees
18 Jan - 19 Jan
Motel 6 La Mesa, CA
Front of property

Heritage Inn La Mesa

Heritage Inn La Mesa
2.0 star property
La Mesa
7.0 out of 10, Good, (1,247 reviews)
"room was clean and staff very friendly"
United States
Charles
The price is RM260
RM287 total
includes taxes & fees
22 Jan - 23 Jan
Heritage Inn La Mesa
Hypo-allergenic bedding, in-room safe, desk, laptop workspace

Holiday Inn Express La Mesa Near SDSU by IHG

Holiday Inn Express La Mesa Near SDSU by IHG
3.0 star property
San Diego
8.2 out of 10, Very good, (463 reviews)
"Great Stay"
United States
Jazmin
The price is RM543
RM599 total
includes taxes & fees
26 Jan - 27 Jan
Holiday Inn Express La Mesa Near SDSU by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top La Mesa Hotel Reviews

San Diego Mission Bay Resort

San Diego Mission Bay Resort

10/10 Excellent
"The staff was great,service was excellent! "
Lisa 3-night trip
Posted 2 days ago
San Diego Mission Bay Resort

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to La Mesa?
Use Expedia and let us help you arrange a flight to San Diego, CA (SEE-Gillespie Field) airport or San Diego, CA (MYF-Montgomery Field) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to get what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that La Mesa has to offer. During your visit, you might want to enjoy the entertainment which La Mesa is known for.
When can I expect good weather in La Mesa?
Planning for the weather is an important factor for making your trip to La Mesa a success, especially when you're splurging. The hottest months are usually August and September, with an average temperature of 22°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for La Mesa is 308 mm.
What's there to see and do in La Mesa?
Enjoy La Mesa with a stop at Mount Helix Park, San Diego Zoo and Mission Bay. If you have a bit of extra time while you're in the area, you might want to check out Petco Park and Port of San Diego.
How can I get around La Mesa?
It's easier to get around town in style when you know your options. Nearby metro stations include La Mesa Boulevard Station, Spring St Trolley Station and 70th St. Trolley Station.

Explore a world of travel with Expedia