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Southeast Missouri Two Star Hotels from RM254

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Check availability on Southeast Missouri 2 Star Hotels

Tonight
14 Oct - 15 Oct
Tomorrow
15 Oct - 16 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Southeast Missouri 2-star hotels

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

1. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Troy
RM294
RM332 total
includes taxes & fees
25 Oct - 26 Oct
Pear Tree Inn Cape Girardeau West
A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.
A hotel reception area with a glass partition, a reception desk, and a digital kiosk.
A gym with cardio equipment, a bench press, and a squat rack.

2. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
United States
stewart
RM222
RM254 total
includes taxes & fees
1 Nov - 2 Nov
Baymont Inn and Suites by Wyndham Farmington, MO
A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.
A hotel lobby with a seating area, a reception desk, and a dining area.
A hotel room with a living area, kitchenette, and a desk with a computer and chair.
A hotel lobby with a reception desk, two red armchairs, a coffee table, a floral centerpiece, and a dining area with wooden tables and chairs.

3. Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
Festus
United States
Michelle
RM291
RM340 total
includes taxes & fees
4 Nov - 5 Nov
Comfort Inn Festus - St Louis South
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
Lobby
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

4. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
David
RM271
RM309 total
includes taxes & fees
21 Oct - 22 Oct
Days Inn and Suites by Wyndham Sikeston
A hotel room with two beds, a nightstand, and a wall-mounted light fixture.
A hotel room with a flat-screen TV, a desk with a chair, a sofa, a small table, and framed pictures on the wall.
Terrace/patio
A compact kitchen with a microwave, a sink, and a small refrigerator.

5. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Rhonda
RM372
RM416 total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Poplar Bluff
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.
A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

6. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Cindy
RM290
RM325 total
includes taxes & fees
27 Oct - 28 Oct
Motel 6 Poplar Bluff, MO
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A motel with a covered entrance, multiple rooms, and a parking lot.
A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

7. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
United States
Laura
RM233
RM266 total
includes taxes & fees
21 Oct - 22 Oct
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.
A hotel breakfast area with a counter, food dispensers, and a refrigerator.
A Holiday Inn Express & Suites building with a covered entrance and multiple windows.
A gym with treadmills, elliptical machines, and weight equipment.

8. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville
United States
Lisa
RM413
RM472 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Perryville by IHG
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

9. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
Rebecca
RM413
RM470 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A modern kitchen with a central island, built-in appliances, and a view into the dining area.
A swimming pool area with a clear pool, a lifeguard chair, and a sign indicating the pool's depth.
A reception desk with a modern design, a digital screen, and a sign indicating 'IHG' branding.
A hotel room with a bed, a desk, a microwave, a coffee maker, and a TV mounted on the wall.

10. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Festus
United States
Terry
RM388
RM444 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

11. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Shelley
RM340
RM387 total
includes taxes & fees
15 Oct - 16 Oct
Best Western Plus Sikeston I-55
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.
A spacious hotel lobby with a dining area, kitchen, and large windows.

12. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
Farmington
United States
CURTIS
RM413
RM473 total
includes taxes & fees
25 Oct - 26 Oct
Crown Pointe Lodge, BW Signature Collection
A modern hotel room with a flat-screen TV, a desk with a chair, a bed with multiple pillows, and a large window with curtains.
A building with a sign that reads "The Farmstead."
A reception desk with a sign reading "The FARMSTEAD," a vending machine with snacks, and a water cooler.
A spacious lobby with a reception desk, a chandelier, and a large window.

13. The Farmstead Hotel

The Farmstead Hotel
Caruthersville
United States
Jack
RM388
RM441 total
includes taxes & fees
19 Oct - 20 Oct
The Farmstead Hotel
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.
A hotel patio with a gazebo, outdoor seating, and a view of the road.

14. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
RM335
RM400 total
includes taxes & fees
25 Oct - 26 Oct
Candlewood Suites Cape Girardeau by IHG
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

15. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
Lori
RM410
RM466 total
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Sikeston
A living room with a sofa, coffee table, and a small table with a vase. There is a window with blinds and a door in the background.
A reception area with a green marble counter, framed certificates on the wall, and a clock.
An indoor swimming pool with a 3 FT depth marker, surrounded by white walls and a ceiling with recessed lighting.
A dining area with a vending machine, a refrigerator, and a counter.

16. Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
Bonne Terre
United States
Elizabeth
RM266
RM292 total
includes taxes & fees
25 Oct - 26 Oct
Super 8 by Wyndham Bonne Terre
A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.
A hotel lobby with a coffee station, seating area, and a television screen.
A hotel room with a bed, a sofa, a small table, and a painting on the wall.
A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

17. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
Poplar Bluff
United States
Muhammad
RM304
RM344 total
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn Poplar Bluff North
A modern retail area with a display of local items and snacks.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

18. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Shannon
RM365
RM416 total
includes taxes & fees
22 Oct - 23 Oct
Tru By Hilton Cape Girardeau
A hotel room with a large bed, two bedside tables, a nightstand, and a framed picture on the wall.
A hotel reception area with a green carpet, a reception desk, a seating area with chairs, and a poster advertising the hotel.
A modern waiting area with a grey sofa, a small table, and a black office chair. There are two doors with signs indicating restrooms.
An indoor swimming pool with clear lanes, a sunlit room with a view, and a staircase leading to an upper level.

19. Quality Inn Farmington

Quality Inn Farmington
Farmington
United States
Tracy
RM223
RM269 total
includes taxes & fees
12 Nov - 13 Nov
Quality Inn Farmington
A modern kitchen with a coffee machine, a refrigerator, and a microwave.
A long, narrow hallway with patterned carpet, doors on both sides, and a ceiling light.
A laundry room with a front-loading washer and dryer, a door, and a light fixture.
A hotel lobby with a reception desk, a blue armchair, a wall-mounted clock, and a framed welcome sign.

20. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington
United States
Marisa
RM243
RM278 total
includes taxes & fees
23 Oct - 24 Oct
Super 8 by Wyndham Farmington
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Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Southeast Missouri.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO
RM408
RM461 total
18 Oct - 19 Oct
includes taxes & fees
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO
RM384
RM442 total
25 Oct - 26 Oct
includes taxes & fees
9.6/10 Exceptional! (1,000 reviews)
Drury Inn & Suites Sikeston, MO
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3003 SOUTH OLD ORCHARD ROAD Jackson MO
RM326
RM353 total
1 Nov - 2 Nov
includes taxes & fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri
A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

8/10 Good
"They let pets stay free!!! No deposit no size limits."
keith 2-night trip
Posted 4 hours ago
Motel 6 Poplar Bluff, MO
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"good, clean, affordable :)"
Nicholas 1-night trip
Posted 23 hours ago
Super 8 by Wyndham Sikeston/Miner Area
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"The room was clean and the staff was very helpful. A great getaway for anyone who likes nature"
Davonne 3-night trip
Posted 5 days ago
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Find out more about Southeast Missouri

Find Your Ideal 2 Star Hotels in Southeast Missouri

When you've got to get away to a new or favourite destination without breaking the bank, Southeast Missouri awaits with top 2 star hotels and a change of scenery. Stay on your feet visiting top attractions that draw several of visitors, or settle in for a hot cuppa nearby and enjoy some R & R. You're about to find out why locals and travellers alike love this place. Pack your bags and get ready for new experiences and a relaxing stay in a city with strong overall 2 star hotels ratings. Guest reviews recommend their 2 star hotels in Southeast Missouri, and it's time to find out why.

The Ideal Hotel at the Perfect Price

Motels are in high demand in Southeast Missouri. You'll find the best deals right here, so book early and save on a great getaway. Thanks to budget-friendly prices and traveller-friendly amenities, past travellers have found an accommodation that's just right. Browse guest reviews to find out what they loved, liked, and can't wait to try again. The best travel is all about hospitality, and these motels have a strong service, these rooms are tidy and cosy. When you book with Expedia, you can stay all over the world, and the journey starts in Southeast Missouri.

Reserve a Stay in a Two-Star Hotel Today!

Book your stay in this popular place today -- Southeast Missouri is a destination on the rise. It's no secret that Southeast Missouri is a great place to stay, so get the best deals while you can, and get to know exactly what everyone loves about Southeast Missouri. Your home away from home is waiting. Book the best deals on 2-star hotels and motels in Southeast Missouri now.

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