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Recommended hotels in Southeast Missouri

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (855)
"Very clean, great check in"
United States
Teresa
The price is RM424
RM479 total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Poplar Bluff

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.8 out of 10, Excellent, (463)
"Nice place "
United States
Debbie
The price is RM349
RM397 total
includes taxes & fees
19 Dec - 20 Dec
The Farmstead Hotel

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very good, (1005)
"Easy parking , quiet and comfortable bed , we’ll stop again on our way back "
United States
joseph
The price is RM309
RM352 total
includes taxes & fees
21 Dec - 22 Dec
Best Western Plus Sikeston

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (669)
"Great place "
United States
GUY
The price is RM344
RM372 total
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (796)
"Staff was kind and provided a lot of information during check out."
United States
Shea
The price is RM409
RM458 total
includes taxes & fees
18 Jan - 19 Jan 2026
Hampton Inn Poplar Bluff

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
The price is RM380
RM430 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Sikeston Southwest by IHG

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (719)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is RM227
RM258 total
includes taxes & fees
21 Dec - 22 Dec
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
"Clean room, great location and friendly staff"
United States
Mark
The price is RM368
RM423 total
includes taxes & fees
23 Dec - 24 Dec
Drury Inn & Suites Sikeston, MO

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
7.8 out of 10, Good, (1000)
"Love the updated rooms and the vending area."
United States
Kathi
The price is RM311
RM328 total
includes taxes & fees
21 Dec - 22 Dec
Motel 6 Poplar Bluff, MO

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is RM368
RM415 total
includes taxes & fees
22 Dec - 23 Dec
Drury Plaza Hotel Cape Girardeau Conference Center

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (445)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is RM399
RM451 total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Sikeston

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (331)
"Staff was very friendly."
United States
Joyce
The price is RM390
RM423 total
includes taxes & fees
19 Dec - 20 Dec
Honeysuckle Inn - Mountain View

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is RM474
RM537 total
includes taxes & fees
27 Dec - 28 Dec
Courtyard by Marriott Cape Girardeau Downtown

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
8.0 out of 10, Very good, (886)
"Staff was very nice ans helpful. Our room was clean and pleasant. "
United States
ELLEN
The price is RM379
RM433 total
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
2.5 star property
Festus
7.8 out of 10, Good, (911)
"Vary clean"
United States
George
The price is RM309
RM361 total
includes taxes & fees
20 Dec - 21 Dec
Comfort Inn Festus - St Louis South

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is RM388
RM438 total
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Shepherd Mountain Inn

Shepherd Mountain Inn
2.5 star property
Ironton
9.4 out of 10, Exceptional, (304)
" Nice room, nice bed, convenient location"
United States
Burton
Shepherd Mountain Inn

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1004)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is RM339
RM358 total
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites Jackson MO

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (726)
"Quiet area and helpful staff. Glad we took a chance on this local hotel while traveling."
United States
Roger
New Orleans Inn Portageville

Echo Bluff State Park

Echo Bluff State Park
2.5 star property
Eminence
9.6 out of 10, Exceptional, (217)
"The cabin was beautiful, comfy, & private! The park was FANTASTIC for hiking & scenery! We hope to return and maybe bring family or friends. The staff were all friendly too! :)"
United States
Joanne
The price is RM650
RM687 total
includes taxes & fees
21 Dec - 22 Dec
Echo Bluff State Park
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Top Southeast Missouri Hotel Reviews

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Southeast Missouri Guest Houses information

Number of reviews
14,234
Accommodation
0 Guest Houses
Lowest Price
RM258
Highest Price
RM687