Southeast Missouri hotels from RM233
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Family friendly
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Our top choices for Southeast Missouri hotels
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (79 reviews)
"The Experience was amazing and we enjoyed the views and the firepit!"
Kenzia
The price is RM377
RM581 total
includes taxes & fees
25 Jun - 26 Jun
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,020 reviews)
"The breakfast and nightly gathering makes this location a fantastic value and will be our choice of stops when heading south again!"
William
The price is RM350
RM370 total
includes taxes & fees
13 Jul - 14 Jul
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (135 reviews)
"This is a clean, quiet, well designed hotel."
Kendra
The price is RM363
RM413 total
includes taxes & fees
2 Jul - 3 Jul
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (202 reviews)
The price is RM377
RM425 total
includes taxes & fees
16 Jul - 17 Jul
Tiny Houses of French Village
Tiny Houses of French VillageFrench Village
10.0 out of 10, Exceptional, (5 reviews)
"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "
Chris
The price is RM903
RM1,376 total
includes taxes & fees
23 Jun - 24 Jun
The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (563 reviews)
"Rooms are very clean. Easy and fast check in"
Kanyia
The price is RM328
RM373 total
includes taxes & fees
22 Jun - 23 Jun
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,003 reviews)
"Wonderful room and food offerings were extra thoughtful."
Jonna
The price is RM406
RM458 total
includes taxes & fees
12 Jul - 13 Jul
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (920 reviews)
"Hotel Staff was very friendly!"
Alice
The price is RM410
RM464 total
includes taxes & fees
19 Jul - 20 Jul
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
9.6 out of 10, Exceptional, (99 reviews)
"It was a very neat experience! Highly recommend you stop here and get away from big chain hotels for a night. The staff were super friendly and the restaurant/store was so nostalgic!"
DANIELLE
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (786 reviews)
"Beautiful hotel at a very good price."
Sheldon
The price is RM377
RM408 total
includes taxes & fees
21 Jun - 22 Jun
Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (875 reviews)
"Nice quiet overnight stay."
Tammy
The price is RM380
RM426 total
includes taxes & fees
19 Jul - 20 Jul
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,000 reviews)
"Great place!"
Jennifer
The price is RM447
RM514 total
includes taxes & fees
21 Jun - 22 Jun
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (362 reviews)
"Simple no frills hotel that we've stayed at a few times while traveling."
Monica
The price is RM402
RM436 total
includes taxes & fees
28 Jun - 29 Jun
The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (599 reviews)
"Always a great place to stay in downtown Cape. Easy access to the local hangouts like Speck Pizza on Broadway."
John
The price is RM538
RM607 total
includes taxes & fees
21 Jun - 22 Jun
Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.2 out of 10, Wonderful, (1,017 reviews)
"Great place to stay. Clean, great staff and the food is good. Would stay again."
Stephanie
The price is RM415
RM469 total
includes taxes & fees
12 Jul - 13 Jul
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (91 reviews)
"Great stay, kind staff, very clean property."
Joni
The price is RM447
RM506 total
includes taxes & fees
2 Jul - 3 Jul
New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very good, (771 reviews)
"Great stay with Great people, very clean and welcoming"
Mircea
The price is RM230
RM249 total
includes taxes & fees
19 Jul - 20 Jul
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (789 reviews)
The price is RM315
RM359 total
includes taxes & fees
21 Jun - 22 Jun
Arcadia Academy
Arcadia AcademyArcadia
9.4 out of 10, Exceptional, (13 reviews)
"We enjoyed ourselves we've been to plenty of places but we had a great excellent time people the room the food and it was great we will be back¡!!!"
John
The price is RM527
RM572 total
includes taxes & fees
23 Jun - 24 Jun
The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (416 reviews)
"It was not at all what I expected. The website showed a very good hotel. It was awful. I would not paid even $40/ night if I knew how awful it is. I felt bad for the ladies working on front desk."
Soheila
The price is RM305
RM338 total
includes taxes & fees
19 Jun - 20 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Holiday Home
10.0 out of 10, Exceptional, (5 reviews)
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Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Clearwater Lake.
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Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Baymont Inn and Suites by Wyndham Farmington, MO
8/10 Good
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is RM254 per night from 24 Jun to 25 Jun
RM254
RM276 total
24 Jun - 25 Jun
includes taxes & fees
8/10 Very Good! (1,004 reviews)
4 Star Hotels
2 properties
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