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Southeast Missouri Hotels with Air Conditioning

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Check availability on Southeast Missouri Hotels with Air Conditioning

Tonight
3 Sept - 4 Sept
Tomorrow
4 Sept - 5 Sept
This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

Our top choices for Southeast Missouri hotels with air conditioning

A motel with a covered entrance, a flag, and a phone number.
A hotel room with two beds, a desk, a chair, a TV, and a bathroom.
A reception desk with a wooden finish, a framed black and white cityscape, and a large framed Eiffel Tower picture.
A living room with a black leather sofa, a wooden coffee table with a vase of flowers, a green potted plant, and a lamp.

1. Madison Inn Lodge

Madison Inn Lodge
Fredericktown
United States
Bawan
RM354
RM387 total
includes taxes & fees
11 Sept - 12 Sept
Madison Inn Lodge
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
A hotel room with two beds, a brick wall, and a wooden headboard.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

2. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Jamie
RM332
RM351 total
includes taxes & fees
21 Sept - 22 Sept
Drury Inn & Suites Jackson MO
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

3. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Scott Andrew
RM380
RM437 total
includes taxes & fees
14 Sept - 15 Sept
Drury Inn & Suites Sikeston, MO
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.
A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.
A corner market with a refrigerated display case and a pantry area.

4. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
Arsenia
RM409
RM462 total
includes taxes & fees
13 Sept - 14 Sept
Fairfield Inn & Suites by Marriott Poplar Bluff
A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, a stove, and a granite countertop.
A bathroom with a white sink, a large mirror, a hairdryer, a coffee maker, and a microwave.
A building with a red awning labeled "Shepherd Mountain Inn."
A compact kitchen with wooden cabinets, a stainless steel refrigerator, and a microwave.

5. Shepherd Mountain Inn

Shepherd Mountain Inn
Ironton
United States
Katie
RM499
RM545 total
includes taxes & fees
4 Sept - 5 Sept
Shepherd Mountain Inn
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

6. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
Canada
Sheila
RM378
RM423 total
includes taxes & fees
13 Sept - 14 Sept
Hampton Inn Poplar Bluff
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

7. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Sandra
RM405
RM456 total
includes taxes & fees
13 Sept - 14 Sept
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a reception desk, seating area, and large windows.
A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

8. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Paul
RM380
RM430 total
includes taxes & fees
10 Sept - 11 Sept
Drury Inn & Suites Poplar Bluff
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A hotel room with two beds, a nightstand, a lamp, and a chair.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

9. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Shawn
RM375
RM406 total
includes taxes & fees
6 Sept - 7 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.
An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.
A hotel room with a large bed, a nightstand with a lamp, a chair, and a desk with a lamp.

10. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
Melissa
RM424
RM480 total
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express & Suites Sikeston Southwest by IHG
View all properties

Top Southeast Missouri Hotel Reviews

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

10/10 Excellent
"We were greeted with a warm smile from a really nice gentleman that checked us in. He chatted with us the entire time we checked in. He gave us ideas where to eat and Lamberts won. The hotel and room was very clean. Breakfast was great. They serve something hot everyday like biscuits and gravy, eggs, sausage and some days bacon. Highly recommend this hotel."
Mary 1-night trip
Posted 1 hour ago
Best Western Plus Sikeston I-55
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Evening sit back with cocktails is amazing and so is the breakfast."
Amanda 1-night trip
Posted 4 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Very nice and clean property."
Julie 2-night trip
Posted 6 hours ago
Drury Inn & Suites Sikeston, MO
Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

8/10 Good
"room was clean and the front staff was nice. place served it's purpose (stayed for only 2 nights). Not much amenitites."
johnny 2-night trip
Posted 17 hours ago
Comfort Inn Festus - St Louis South
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"Quick check in, Friendly Staff. AC was cold. Breakfast was good, preparer was friendly."
joseph 1-night trip
Posted 1 day ago
Pear Tree Inn Cape Girardeau West
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"This location is a must stay any time I am traveling in the area. The staff are helpful. There are lots of dinning options near by. I can always count on a peaceful night sleep at this location."
Jesse 1-night trip
Posted 1 day ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"Front desk was welcoming and nice. Room was cleaned, beds were comfy. Very spacious. Quiet as well."
Tristan 1-night trip
Posted 2 days ago
Days Inn and Suites by Wyndham Sikeston

Frequently asked questions

How much do hotels with air conditioning in Southeast Missouri cost?
You'll pay between RM250 and RM648 per night for hotels with air conditioning in Southeast Missouri. Whatever your travel plans and budget, your dream stay is only a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best hotels with air conditioning in Southeast Missouri?
Southeast Missouri offers multiple hotels with air conditioning, with a total average guest review rating of 9.0. Organising a trip to Cape Girardeau? Reserve a room at Hampton Inn Cape Girardeau I 55 East, a highly rated 2.5-stars property with pool sun loungers and a dining venue. Another recommended option where you'll be able to relax in air-conditioned comfort is Drury Plaza Hotel Cape Girardeau Conference Centre. It has a 3-stars rating and conveniences such as a swimming pool and a spa tub.
How many hotels with air conditioning are there in Southeast Missouri?
Take a peek at our 71 hotels with AC in Southeast Missouri and lock in your favourite. Whether you're planning a holiday with the fam or a weekend with friends, your perfect stay is just a few clicks away with Expedia.
What are the best cheap hotels with air conditioning in Southeast Missouri?
With hotels with air conditioning starting from just RM250 per night, you'll have more cash in your pocket for exploring Southeast Missouri. If Cape Girardeau is on your travel agenda, book a room at Hampton Inn Cape Girardeau I 55 East. A terrace, a swimming pool and in-room air conditioning help make this property a popular choice. You'll also discover low-cost hotels with air conditioning in Sikeston. Chill out at Pear Tree Inn Sikeston and take advantage of handy amenities like a swimming pool and front desk services. Explore Southeast Missouri on the cheap by filling your sightseeing itinerary with awesome free attractions. Hunter Valley Winery in Cape Girardeau is a must. If you're spending some time in Sikeston, you can leave your wallet in your pocket when visiting Sikeston Depot Museum. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels with air conditioning in Southeast Missouri?
You'll discover some very comfortable family-friendly hotels with air conditioning in Southeast Missouri. If you're on your way to Cape Girardeau, have a look at Drury Plaza Hotel Cape Girardeau Conference Centre. Providing air-conditioned rooms and conveniences like complimentary breakfast and WiFi, your team will feel right at home at this 3-stars stay. Pear Tree Inn Cape Girardeau West is another great pick for families in Cape Girardeau. This 2.5-stars option offers complimentary breakfast, a laundry service and air conditioning. Once you've unpacked your suitcase and settled in, start sightseeing around Cape Girardeau. Look forward to memorable days out at family-friendly attractions such as Cape Splash Family Aquatic Centre and Lazy L Safari Park.
Why book your hotel with air conditioning in Southeast Missouri with Expedia?
Reserving a hotel with air conditioning in Southeast Missouri is as easy as working out your travel dates and selecting from our range of suitable options. On the lookout for something luxurious or affordable, or a stay that also includes free WiFi? Use Expedia's filters to fine-tune your search results and find your perfect pad with AC and more.
How can I find cheap hotels with air conditioning in Southeast Missouri?
With Expedia's nifty filter tool, scoring cheap hotels with air conditioning in Southeast Missouri has never been easier. To view accommodation with AC that'll make your wallet happy, narrow down your search by star rating and budget.
What is there to do in Southeast Missouri near my hotel with air conditioning?
Whatever you're interested in, there are almost endless things to do in Southeast Missouri. If you're making your way to Cape Girardeau, drop by Isle Casino Cape Girardeau, Show Me Centre and Riverfront Park. Spending your holiday in Sikeston? Sikeston Depot Museum, Central Park and The Book Bug are popular attractions here.

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