Serra Mesa

San Diego


Popular places to visit

Things to do


Top hotels in Serra Mesa

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
8/10 Very Good! (1,930 reviews)
"Very clean, staff very caring and polite. Very convenient to old town and downtown San Diego."

Reviewed on 29 Jul 2025

Handlery Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is RM644 per night from 3 Aug to 4 Aug
RM644
RM868 total
3 Aug - 4 Aug
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,795 reviews)
"Loved everything! Wish I spent more time here!"

Reviewed on 28 Jul 2025

Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is RM860 per night from 28 Aug to 29 Aug
RM860
RM1,225 total
28 Aug - 29 Aug
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,810 reviews)
"Just the perfect area with a view."

Reviewed on 28 Jul 2025

Manchester Grand Hyatt San Diego
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is RM701 per night from 25 Aug to 26 Aug
RM701
RM806 total
25 Aug - 26 Aug
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,610 reviews)
"They property was really nice and the rooms were clean, spacious and well kept. The pool are was in a great location and our kids enjoyed it. It's not walkable to anything else but in a good central location to drive to spots we were interested in. They did discount our parking but honestly, not ..."

Reviewed on 29 Jul 2025

The Dana on Mission Bay
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4 out of 5
333 W Harbor Dr, San Diego, CA
The price is RM987 per night from 17 Aug to 18 Aug
RM987
RM1,333 total
17 Aug - 18 Aug
includes taxes & fees
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,785 reviews)
"Tons to do around the area. Pool is great . Bit pricy on food and drinks but lots of options outside"

Reviewed on 29 Jul 2025

Marriott Marquis San Diego Marina
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real, San Diego, CA
The price is RM596 per night from 10 Aug to 11 Aug
RM596
RM679 total
10 Aug - 11 Aug
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
8/10 Very Good! (1,327 reviews)
"Our AC did not work however we made it a fun trip. We did have to rent a car to get around but it was not an issue. Relaxing and overall has a decent stay."

Reviewed on 29 Jul 2025

DoubleTree by Hilton San Diego - Del Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Serra Mesa

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Mission Valley

4/5(36 area reviews)

Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Fashion Valley Mall and Snapdragon Stadium, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.

Mission Valley
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North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park
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Hillcrest

5/5(1 area review)

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest
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Del Cerro

While there might not be top attractions in Del Cerro, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.

Del Cerro
Old Town San Diego State Park featuring signage

Old Town San Diego

4/5(5 area reviews)

The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.

Old Town San Diego
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Mid-City

While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.

Mid-City

Serra Mesa