Serra Mesa

San Diego

Aerial view of house in Serra Mesa City in San Diego, California, USA. Green Dry Valley and Villas
Aerial view of house in Serra Mesa City in San Diego, California, USA. Green Dry Valley and Villas

Popular places to visit

Things to do


Top hotels in Serra Mesa

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is RM784 per night from 5 Apr to 6 Apr
RM784
RM1,110 total
5 Apr - 6 Apr
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.8/10 Excellent! (2,448 reviews)
Always love coming here. Perfect for families. Lots of activities and things for kids and adults to do without even leaving the resort. Great location, views, everything!

Reviewed on 7 Mar 2026

Paradise Point Resort & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
The price is RM287 per night from 22 Mar to 23 Mar
RM287
RM330 total
22 Mar - 23 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, free parking and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. ...
8/10 Very Good! (3,272 reviews)
I liked the selection of TV channels, it even had a YouTube app, which I watch more than anything else since COVID-19. Even though the hotel is located next to freeway, it was a pleasant stay, and I slept well.

Reviewed on 8 Mar 2026

Best Western Seven Seas
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is RM892 per night from 11 Mar to 12 Mar
RM892
RM1,224 total
11 Mar - 12 Mar
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and a nightclub. Our guests praise the helpful staff and the convenient parking in their reviews. ...
9/10 Wonderful! (3,390 reviews)
We stayed for 2 nights (Fri-Sun). We stayed in the King Suite. The room was very clean, bathroom area was very clean, but not enough room in fridge for guests personal items storage, no microwave, but it wasn’t needed. The staff was very kind. The pool area was clean, as was the pool. Only suggestion ...

Reviewed on 8 Mar 2026

Hard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
The price is RM480 per night from 7 Apr to 8 Apr
RM480
RM556 total
7 Apr - 8 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
9/10 Wonderful! (1,163 reviews)
Enjoyed my stay and the hotel offered basic amenities. Only downside is that there is no microwave on site at the hotel

Reviewed on 7 Mar 2026

The DEXTRO Little Italy, BW Premier Collection
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
The price is RM370 per night from 10 Mar to 11 Mar
RM370
RM425 total
10 Mar - 11 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, a fitness centre and parking (surcharge). Our guests praise the helpful staff and the clean ...
8/10 Very Good! (2,536 reviews)
Good stay

Reviewed on 6 Mar 2026

Days Inn by Wyndham San Diego Hotel Circle
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is RM466 per night from 1 Apr to 2 Apr
RM466
RM536 total
1 Apr - 2 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ...
8.2/10 Very Good! (2,337 reviews)
Bathrooms were dirty. U don’t like carp d rooms. And they had no water bottle in the rooms for guest. The vending machines in my wing were out of drinks in general. I was not impressed.

Reviewed on 6 Mar 2026

Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Serra Mesa

Closeup of the Adobe walls of the historic Mission De Alcala San Diego California

Mission Valley

4/5(36 area reviews)

Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Mission Valley Mall and Fashion Valley Mall, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.

Mission Valley
SanDiego_NorthPark_6346499_001

North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park
Gossip Grill

Hillcrest

5/5(1 area review)

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest
I didn’t go in as I felt the outside was pretty great already. Good area of town for a self-guided walking tour.

Old Town San Diego

4/5(5 area reviews)

The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.

Old Town San Diego
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Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Mission Bay
Little Italy

Little Italy

Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.

Little Italy


Serra Mesa

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