A residential area with houses, roads, and a hilly landscape.

Hotels in Serra Mesa, San Diego

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Our top choices for Serra Mesa hotels

1. Courtyard by Marriott San Diego Central

Courtyard by Marriott San Diego Central
3.0 star property
2.6 km from Serra Mesa
8.8 out of 10, Excellent, (1,001 reviews)
"Excellent hotel!!!! Very clean and the staff was very helpful!!!!!"
United States
Nassim
The price is RM567
RM651 total
includes taxes & fees
4 Oct - 5 Oct
Courtyard by Marriott San Diego Central

2. DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
4.2 km from Serra Mesa
8.4 out of 10, Very good, (1,815 reviews)
"Great location"
United States
Victor
The price is RM564
RM648 total
includes taxes & fees
27 Sept - 28 Sept
DoubleTree by Hilton Hotel San Diego - Mission Valley

3. Town and Country San Diego

Town and Country San Diego
4.0 star property
5.3 km from Serra Mesa
8.6 out of 10, Excellent, (1,874 reviews)
"Enjoyed our stay"
United States
Sol
The price is RM860
RM1,129 total
includes taxes & fees
18 Sept - 19 Sept
Town and Country San Diego

4. Pleasant Inn

Pleasant Inn
2.5 star property
4.8 km from Serra Mesa
8.6 out of 10, Excellent, (1,560 reviews)
"Great place to stay for your trip!"
United States
Vance Lee
The price is RM335
RM385 total
includes taxes & fees
13 Sept - 14 Sept
Pleasant Inn

5. Best Western Seven Seas

Best Western Seven Seas
3.0 star property
5.3 km from Serra Mesa
8.0 out of 10, Very good, (3,901 reviews)
"Great staff, cold room, nice amenities."
United States
Jamie
The price is RM344
RM395 total
includes taxes & fees
13 Sept - 14 Sept
Best Western Seven Seas

6. Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
7.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,085 reviews)
"Amazing stay."
United States
Faleoalii Iereneo
The price is RM573
RM659 total
includes taxes & fees
23 Sept - 24 Sept
Holiday Inn Express San Diego Airport - Old Town by IHG

7. Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
3.0 star property
6.4 km from Serra Mesa
8.8 out of 10, Excellent, (1,714 reviews)
"It was a great stay!"
United States
Demetrius
The price is RM554
RM637 total
includes taxes & fees
20 Sept - 21 Sept
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

8. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City, 10.3 km from Serra Mesa
8.8 out of 10, Excellent, (2,048 reviews)
"Clean room, nice staff, breakfast is really good"
United States
Sarineh
The price is RM722
RM946 total
includes taxes & fees
13 Sept - 14 Sept
Embassy Suites by Hilton San Diego La Jolla

9. Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
Old Town San Diego, 7.4 km from Serra Mesa
8.8 out of 10, Excellent, (1,501 reviews)
"great location, excellent hotel"
United States
Edward Palacios
The price is RM537
RM617 total
includes taxes & fees
27 Sept - 28 Sept
Hilton Garden Inn San Diego Old Town/SeaWorld Area

10. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
5.8 km from Serra Mesa
9.2 out of 10, Wonderful, (3,098 reviews)
"Always enjoy my stay here"
United States
amy
The price is RM650
RM748 total
includes taxes & fees
23 Sept - 24 Sept
Legacy Resort Hotel & Spa

11. Fairfield Inn & Suites San Diego Old Town

Fairfield Inn & Suites San Diego Old Town
3.0 star property
Old Town San Diego, 7.8 km from Serra Mesa
8.8 out of 10, Excellent, (1,180 reviews)
"Overall, great place to stay."
United States
David
The price is RM585
RM672 total
includes taxes & fees
27 Sept - 28 Sept
Fairfield Inn & Suites San Diego Old Town

12. Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
10.6 km from Serra Mesa
9.2 out of 10, Wonderful, (1,711 reviews)
"Loved the staff and location."
United States
David
The price is RM763
RM877 total
includes taxes & fees
28 Sept - 29 Sept
Hampton Inn & Suites San Diego Airport Liberty Station

13. Lamplighter Inn & Suites at SDSU

Lamplighter Inn & Suites at SDSU
2.5 star property
8.4 km from Serra Mesa
9.0 out of 10, Wonderful, (1,427 reviews)
"Great stay"
United States
Bernadette
The price is RM534
RM602 total
includes taxes & fees
7 Oct - 8 Oct
Lamplighter Inn & Suites at SDSU

14. Kings Inn San Diego

Kings Inn San Diego
2.5 star property
6 km from Serra Mesa
8.8 out of 10, Excellent, (3,746 reviews)
"Love this hotel, will be back endlessly love it here!"
United States
Armando
The price is RM330
RM379 total
includes taxes & fees
13 Oct - 14 Oct
Kings Inn San Diego

15. Best Western San Diego/Miramar Hotel

Best Western San Diego/Miramar Hotel
2.5 star property
10.1 km from Serra Mesa
8.0 out of 10, Very good, (1,539 reviews)
"Great place to stay"
United States
Jesus
The price is RM441
RM507 total
includes taxes & fees
13 Sept - 14 Sept
Best Western San Diego/Miramar Hotel

16. Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG

Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG
2.5 star property
11.7 km from Serra Mesa
8.8 out of 10, Excellent, (1,001 reviews)
"Solid place to stay"
United States
Johnathan
The price is RM516
RM593 total
includes taxes & fees
13 Sept - 14 Sept
Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG

17. California Suites Hotel

California Suites Hotel
2.0 star property
4.8 km from Serra Mesa
8.0 out of 10, Very good, (2,929 reviews)
"Great place to stay"
United States
Mathew
The price is RM326
RM374 total
includes taxes & fees
14 Sept - 15 Sept
California Suites Hotel

18. Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
5.3 km from Serra Mesa
9.4 out of 10, Exceptional, (1,986 reviews)
"Amazing hotel! Will for sure be staying here again!"
United States
Bryanna
The price is RM1,014
RM1,165 total
includes taxes & fees
30 Sept - 1 Oct
Lafayette Hotel & Club

19. Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town
4.0 star property
8.2 km from Serra Mesa
9.2 out of 10, Wonderful, (1,315 reviews)
"Great place to stay. Great price always happy with our stay."
United States
Joshua
The price is RM631
RM725 total
includes taxes & fees
20 Sept - 21 Sept
Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

20. Handlery Hotel

Handlery Hotel
3.5 star property
5.7 km from Serra Mesa
8.4 out of 10, Very good, (2,892 reviews)
"Great place would book again."
United States
Ronald
The price is RM441
RM554 total
includes taxes & fees
7 Oct - 8 Oct
Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most. Learn more about Serra Mesa
Learn more about Serra Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 40 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Sharp Learning Resource Center and Convoy District are also worth a stop.

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