
Hotels in Serra Mesa, San Diego
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Our top choices for Serra Mesa hotels

Wyndham San Diego Bayside
Wyndham San Diego Bayside
The Bristol Hotel San Diego
The Bristol Hotel San Diego
San Diego Mission Bay Resort
San Diego Mission Bay Resort
Paradise Point Resort & Spa
Paradise Point Resort & Spa
Sycuan Casino Resort
Sycuan Casino Resort
Loews Coronado Bay Resort
Loews Coronado Bay Resort
Hard Rock Hotel San Diego
Hard Rock Hotel San Diego
The Dana on Mission Bay
The Dana on Mission Bay
The DEXTRO Little Italy, BW Premier Collection
The DEXTRO Little Italy, BW Premier Collection
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego
Humphreys Half Moon Inn
Humphreys Half Moon Inn
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
GreenTree Inn San Diego Mission Bay
GreenTree Inn San Diego Mission Bay
Embassy Suites by Hilton San Diego Bay Downtown
Embassy Suites by Hilton San Diego Bay Downtown
Hampton Inn San Diego/Mission Valley
Hampton Inn San Diego/Mission Valley
DoubleTree by Hilton San Diego - Del Mar
DoubleTree by Hilton San Diego - Del Mar
Margaritaville Hotel San Diego Gaslamp Quarter
Margaritaville Hotel San Diego Gaslamp Quarter
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld
Best Western Seven Seas
Best Western Seven SeasWhere to stay in Serra Mesa

Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter
The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach
With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.
Top Serra Mesa Hotel Reviews

























































































