Southeast Missouri hotels from RM233
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Our top choices for Southeast Missouri hotels
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,010 reviews)
"Breakfast was good,pool hot tub excellent "
Janica
The price is RM452
RM519 total
includes taxes & fees
28 Jun - 29 Jun
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,009 reviews)
"Very clean, helpful staff"
Cathy
The price is RM406
RM458 total
includes taxes & fees
5 Jul - 6 Jul
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (913 reviews)
"Hotel Staff was very friendly!"
Alice
The price is RM410
RM463 total
includes taxes & fees
14 Jun - 15 Jun
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
"The room was very spacious and great water pressure. Staff very kind to us, the breakfast was great as well"
Theresa
The price is RM447
RM504 total
includes taxes & fees
14 Jun - 15 Jun
Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (870 reviews)
"Nice quiet overnight stay."
Tammy
The price is RM380
RM425 total
includes taxes & fees
5 Jul - 6 Jul
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (516 reviews)
"Great stay!!"
Taylor
The price is RM509
RM577 total
includes taxes & fees
4 Jul - 5 Jul
Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (576 reviews)
"Very clean hotel with comfortable bedding. Front desk staff was very nice and accommodating as we were traveling with a small dog."
Connie
The price is RM414
RM469 total
includes taxes & fees
12 Jul - 13 Jul
Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.2 out of 10, Wonderful, (1,010 reviews)
"Great place to stay. Clean, great staff and the food is good. Would stay again."
Stephanie
The price is RM419
RM473 total
includes taxes & fees
12 Jul - 13 Jul
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (84 reviews)
"Great stay, kind staff, very clean property."
Joni
The price is RM447
RM506 total
includes taxes & fees
2 Jul - 3 Jul
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (779 reviews)
"Beautiful hotel at a very good price."
Sheldon
The price is RM376
RM407 total
includes taxes & fees
22 Jun - 23 Jun
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,016 reviews)
"The breakfast and nightly gathering makes this location a fantastic value and will be our choice of stops when heading south again!"
William
The price is RM325
RM343 total
includes taxes & fees
28 Jun - 29 Jun
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,012 reviews)
"I will definitely be staying here next time I visit SEMO."
Lee
The price is RM387
RM436 total
includes taxes & fees
12 Jul - 13 Jul
The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (595 reviews)
"Always a great place to stay in downtown Cape. Easy access to the local hangouts like Speck Pizza on Broadway."
John
The price is RM537
RM606 total
includes taxes & fees
17 Jun - 18 Jun
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (467 reviews)
"Only stayed one night, no complaints"
Zachary
The price is RM411
RM465 total
includes taxes & fees
12 Jul - 13 Jul
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
8.0 out of 10, Very good, (1,001 reviews)
"Clean room, check in was easy. It was a good stopover for 1 night."
Nancy
The price is RM342
RM391 total
includes taxes & fees
22 Jun - 23 Jun
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (134 reviews)
"This is a clean, quiet, well designed hotel."
Kendra
The price is RM363
RM413 total
includes taxes & fees
2 Jul - 3 Jul
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (822 reviews)
"A nice stay"
DAVID
The price is RM430
RM485 total
includes taxes & fees
2 Jul - 3 Jul
Hampton Inn Farmington
Hampton Inn FarmingtonFarmington
8.8 out of 10, Excellent, (560 reviews)
"The room was spotless, staff and front desk were very friendly and helpful. Breakfast was good. I stay here once or twice a year and always happy with my stay"
Kathy
The price is RM495
RM539 total
includes taxes & fees
28 Jun - 29 Jun
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (196 reviews)
"The hotel was super clean, very friendly, the beds were very comfortable."
Candia
The price is RM376
RM424 total
includes taxes & fees
25 Jun - 26 Jun
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
8.0 out of 10, Very good, (1,000 reviews)
"Clean and parking was easy."
Amy
The price is RM305
RM341 total
includes taxes & fees
14 Jun - 15 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (75 reviews)
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Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Clearwater Lake.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Baymont Inn and Suites by Wyndham Farmington, MO
6/10 Okay
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is RM254 per night from 18 Jun to 19 Jun
RM254
RM276 total
18 Jun - 19 Jun
includes taxes & fees
8/10 Very Good! (1,010 reviews)
4 Star Hotels
2 properties
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