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SpringHill Suites Houston Medical Center/NRG Park

1400 Old Spanish Trl Houston TX

20 min walk from MD Anderson Cancer Center

Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...

8.8/10 Excellent! (1,008 reviews)

"The room was a little warm. The front room needs an extra a/c so that it can cool down faster. Otherwise, it was a great hotel. Good breakfast. Clean."

Reviewed on 5 Aug 2026

Hyatt Place Houston/Galleria

5252 W. Alabama Houston TX

5 min drive from MD Anderson Cancer Center

Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in ...

8.8/10 Excellent! (1,550 reviews)

"The staff was so very helpful and we appreciate the assistance that was provided for my disabled husband."

Reviewed on 4 Aug 2026

DoubleTree by Hilton Houston Medical Center Hotel & Suites

6800 Main Street Houston TX

2 min walk from MD Anderson Cancer Center

Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff in ...

8.4/10 Very good! (654 reviews)

"Very nice hotel to stay in and had warm cookies which was a nice treat ."

Reviewed on 5 Aug 2026

See all 1,334 properties in Southwest Houston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.