Sikeston

Travel Guide

Good Day Sunshine Early Morning Sunshine passes through the fog and scatters through the leaves of a tree in Scott County Missouri
Pre-teen girl walking through corn maze during fall
Columns and Dogwood Trees. Columns from an old church surrounded by colorful dog wood trees in full bloom
Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is RM435 per night from 26 Apr to 27 Apr
RM435
RM500 total
26 Apr - 27 Apr
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,003 reviews)
👍

Reviewed on 19 Apr 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is RM418 per night from 15 May to 16 May
RM418
RM473 total
15 May - 16 May
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (544 reviews)
Property was pet friendly. They have nice dog park in the back of the building.

Reviewed on 24 Apr 2026

Hampton Inn Sikeston
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
The price is RM257 per night from 26 Apr to 27 Apr
RM257
RM293 total
26 Apr - 27 Apr
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
7.2/10 Good! (1,001 reviews)
I stayed in Room 214. The room was clean, but there were some furniture and appliance problems. The smoke detector in the off room with the sofa was disconnected from the ceiling and hanging by its wires. The caulking around the sink in the bathroom was coming a loose. The hair drier was melted at ...

Reviewed on 21 Apr 2026

Days Inn and Suites by Wyndham Sikeston
See all 299 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel

2 out of 5
112 W Ste Maries St Perryville MO
Stay at this aparthotel in Perryville. Enjoy free Wi-Fi, free parking and bathrobes. Popular attractions Feltz Street Park and Perryville Country Club are located ...
8/10 Very Good! (1 review)
I like it but there is room for improvement on the little things. For a personal stay and non business it would be a little better. I have stayed twice for business. It’s clean but due to the openness it’s hard to control the temp in the room. My first stay the wifi didn’t work and cell reception ...

Reviewed on 16 Apr 2026

The Atrium - A Boutique Hotel
Urban Lofts

Urban Lofts

3 out of 5
102 N Jackson St Perryville MO
Stay at this aparthotel in Perryville. Enjoy free Wi-Fi, free parking and dry cleaning or laundry services. Popular attractions Feltz Street Park and Perryville ...
9.2/10 Wonderful! (18 reviews)
Beautiful place and staff was amazing!

Reviewed on 16 Apr 2026

Urban Lofts
See all properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Sikeston Depot Museum

You can spend time studying the exhibits at Sikeston Depot Museum during your travels in Sikeston. While in this family-friendly area, you can savour the top-notch restaurants.

Sikeston Depot Museum

Central Park

Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savour the top-notch restaurants.

Central Park

City of Miner Convention Center

Learn about the events happening in City of Miner Convention Center during your trip to Miner. While in this family-friendly area, you can savour the top-notch restaurants.

City of Miner Convention Center

Other places like Sikeston

Explore a world of travel with Expedia