Hotels in Medical Center, Detroit

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14 Dec - 15 Dec
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15 Dec - 16 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Medical Center hotels

Lobby
La Quinta Inn & Suites by Wyndham Detroit Metro Airport

La Quinta Inn & Suites by Wyndham Detroit Metro Airport

La Quinta Inn & Suites by Wyndham Detroit Metro Airport
3.0 star property
26.6 km from Medical Center
8.4 out of 10, Very good, (2196)
"We have stayed here several times, and we have been pleased each time."
Canada
Sharon
The price is RM374
RM417 total
includes taxes & fees
17 Dec - 18 Dec
La Quinta Inn & Suites by Wyndham Detroit Metro Airport
3 bars/lounges
The Godfrey Detroit, Curio Collection By Hilton

The Godfrey Detroit, Curio Collection By Hilton

The Godfrey Detroit, Curio Collection By Hilton
4.0 star property
Corktown, 2.8 km from Medical Center
9.0 out of 10, Wonderful, (1754)
"Nice place"
United States
Dean
The price is RM365
RM423 total
includes taxes & fees
24 Dec - 25 Dec
The Godfrey Detroit, Curio Collection By Hilton
Lobby sitting area
Comfort Inn Metro Airport

Comfort Inn Metro Airport

Comfort Inn Metro Airport
3.5 star property
27.6 km from Medical Center
7.8 out of 10, Good, (1344)
"This hotel is very clean and worth the price."
United States
Jason
The price is RM273
RM317 total
includes taxes & fees
13 Jan - 14 Jan 2026
Comfort Inn Metro Airport
Exterior
The Westin Southfield Detroit

The Westin Southfield Detroit

The Westin Southfield Detroit
4.0 star property
20.6 km from Medical Center
8.4 out of 10, Very good, (1170)
"Room was clean, staff was friendly. Would stay there again."
United States
Ryan
The price is RM414
RM472 total
includes taxes & fees
26 Dec - 27 Dec
The Westin Southfield Detroit
Exterior
Trumbull and Porter Hotel

Trumbull and Porter Hotel

Trumbull and Porter Hotel
3.5 star property
Corktown, 3.2 km from Medical Center
8.0 out of 10, Very good, (1005)
"Courteous staff, super comfortable beds & immaculately clean rooms."
United States
Courtney
Trumbull and Porter Hotel
5 bars/lounges
Hollywood Casino at Greektown

Hollywood Casino at Greektown

Hollywood Casino at Greektown
4.0 star property
Greektown Historic District, 2.4 km from Medical Center
8.6 out of 10, Excellent, (4908)
"Nice boutique style hotel."
United States
Tonya
The price is RM557
RM759 total
includes taxes & fees
16 Dec - 17 Dec
Hollywood Casino at Greektown
Lobby
Tru by Hilton Troy Detroit

Tru by Hilton Troy Detroit

Tru by Hilton Troy Detroit
2.5 star property
22.3 km from Medical Center
8.6 out of 10, Excellent, (1004)
"Clean room, nice bed, very nice breakfast, nice staff."
United States
Jeffrey
The price is RM341
RM377 total
includes taxes & fees
21 Dec - 22 Dec
Tru by Hilton Troy Detroit
Exterior
Holiday Inn Detroit Metro Airport by IHG

Holiday Inn Detroit Metro Airport by IHG

Holiday Inn Detroit Metro Airport by IHG
3.0 star property
27.2 km from Medical Center
8.6 out of 10, Excellent, (1002)
"Very helpful staff, great airport location. "
United States
Anthony
The price is RM365
RM407 total
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Detroit Metro Airport by IHG
Free daily continental breakfast
Baymont by Wyndham Detroit Airport/Romulus

Baymont by Wyndham Detroit Airport/Romulus

Baymont by Wyndham Detroit Airport/Romulus
2.5 star property
27.3 km from Medical Center
7.8 out of 10, Good, (1725)
"Friendly and helpful staff at check in"
United States
Nancy
The price is RM285
RM318 total
includes taxes & fees
10 Jan - 11 Jan 2026
Baymont by Wyndham Detroit Airport/Romulus
Reception
Hampton Inn & Suites Detroit / Airport - Romulus

Hampton Inn & Suites Detroit / Airport - Romulus

Hampton Inn & Suites Detroit / Airport - Romulus
2.5 star property
27.2 km from Medical Center
9.2 out of 10, Wonderful, (1167)
"Nice rooms, well maintain hotel"
Canada
Michael
The price is RM429
RM479 total
includes taxes & fees
29 Dec - 30 Dec
Hampton Inn & Suites Detroit / Airport - Romulus
Reception
Skyline Hotel Detroit Airport, SureStay Collection by BW

Skyline Hotel Detroit Airport, SureStay Collection by BW

Skyline Hotel Detroit Airport, SureStay Collection by BW
2.5 star property
27.3 km from Medical Center
8.2 out of 10, Very good, (1005)
"The Skyline Hotel was good"
United States
Wayne
The price is RM492
RM565 total
includes taxes & fees
21 Dec - 22 Dec
Skyline Hotel Detroit Airport, SureStay Collection by BW
2 restaurants, breakfast, lunch, dinner served; Mediterranean cuisine
Cambria Hotel Detroit Downtown

Cambria Hotel Detroit Downtown

Cambria Hotel Detroit Downtown
4.0 star property
Downtown Detroit, 2.8 km from Medical Center
9.4 out of 10, Exceptional, (940)
"Definitely would stay here again"
United States
Christine
The price is RM476
RM554 total
includes taxes & fees
22 Dec - 23 Dec
Cambria Hotel Detroit Downtown
Exterior
Holiday Inn Express Romulus / Detroit Airport by IHG

Holiday Inn Express Romulus / Detroit Airport by IHG

Holiday Inn Express Romulus / Detroit Airport by IHG
2.5 star property
26.9 km from Medical Center
8.2 out of 10, Very good, (1005)
"Great staff very friendly "
United States
Rhea
The price is RM365
RM407 total
includes taxes & fees
27 Dec - 28 Dec
Holiday Inn Express Romulus / Detroit Airport by IHG
Lobby
Atheneum Suite Hotel

Atheneum Suite Hotel

Atheneum Suite Hotel
4.0 star property
Greektown Historic District, 2.5 km from Medical Center
9.2 out of 10, Wonderful, (2046)
"Nice clean rooms, staff was great"
United States
Benjamin
Atheneum Suite Hotel
Lobby
Sheraton Detroit Metro Airport

Sheraton Detroit Metro Airport

Sheraton Detroit Metro Airport
3.5 star property
27 km from Medical Center
8.4 out of 10, Very good, (1004)
"Great hotel. Nice restaurant/bar. Clean Rooms. Will go again."
United States
Deborah
The price is RM456
RM548 total
includes taxes & fees
19 Dec - 20 Dec
Sheraton Detroit Metro Airport
Desk, blackout curtains, soundproofing, iron/ironing board
SpringHill Suites by Marriott Detroit Dearborn

SpringHill Suites by Marriott Detroit Dearborn

SpringHill Suites by Marriott Detroit Dearborn
3.0 star property
13.2 km from Medical Center
8.8 out of 10, Excellent, (639)
"Had a nice one night stay for a concert. Hotel was very clean and staff was nice and helpful"
United States
Laneesha
The price is RM438
RM489 total
includes taxes & fees
27 Dec - 28 Dec
SpringHill Suites by Marriott Detroit Dearborn
Premium bedding, desk, laptop workspace, blackout curtains
Wingate by Wyndham Utica

Wingate by Wyndham Utica

Wingate by Wyndham Utica
2.5 star property
30.4 km from Medical Center
8.4 out of 10, Very good, (1004)
"Rooms were clean and staff was friendly. "
United States
Thomas
The price is RM312
RM344 total
includes taxes & fees
16 Dec - 17 Dec
Wingate by Wyndham Utica
Free daily buffet breakfast
Comfort Inn Near Greenfield Village

Comfort Inn Near Greenfield Village

Comfort Inn Near Greenfield Village
2.5 star property
15.5 km from Medical Center
7.2 out of 10, Good, (1000)
"Clean room, nice breakfast, clean pool, plenty of free parking "
United States
Jeffrey
The price is RM289
RM322 total
includes taxes & fees
25 Dec - 26 Dec
Comfort Inn Near Greenfield Village
Full-sized fridge, microwave, coffee/tea maker, cookware/dishes/utensils
Sonesta Simply Suites Detroit Troy

Sonesta Simply Suites Detroit Troy

Sonesta Simply Suites Detroit Troy
2.0 star property
24.1 km from Medical Center
8.0 out of 10, Very good, (1005)
"Yes , very nice stay! "
United States
Tamica
The price is RM262
RM290 total
includes taxes & fees
22 Dec - 23 Dec
Sonesta Simply Suites Detroit Troy
Breakfast, lunch, dinner served; American cuisine
Fort Pontchartrain Detroit, a Wyndham Hotel

Fort Pontchartrain Detroit, a Wyndham Hotel

Fort Pontchartrain Detroit, a Wyndham Hotel
3.5 star property
Downtown Detroit, 3.1 km from Medical Center
8.4 out of 10, Very good, (2327)
"Decent place to stay and fairly priced."
United States
Gregory
The price is RM554
RM642 total
includes taxes & fees
4 Jan - 5 Jan 2026
Fort Pontchartrain Detroit, a Wyndham Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Medical Center

Find the best Medical Center areas for the activities you enjoy most.

Downtown Detroit

Detroit is known for its architecture, industrialization and the arts. As creative entrepreneurs reclaim downtown, a new urban culture is rising next to the old.

Rochester Hills

Live music, restaurants and shopping are some highlights of Rochester Hills. Make a stop by The Village Of Rochester Hills or Meadow Brook Amphitheatre while you're exploring.

Midtown

If you're spending time in Midtown, check out sights like The Majestic Theatre or Detroit Masonic Temple and hop on the metro to see more of the city at Canfield Street Station or Martin Luther King Boulevard/Mack Avenue Station.

Corktown

Travellers enjoy Corktown for its live music and historical sites. Consider checking out Michigan Central while you're in the area.

Brush Park

Brush Park might not have many top sights, but Ford Field and Little Caesars Arena are two attractions nearby that you can check out.

Top Medical Center Hotel Reviews

The Siren Hotel, an Ash Hotel

The Siren Hotel, an Ash Hotel

10/10 Excellent
"I really enjoyed my stay at the Siren hotel"
Elisabeth 1-night trip
Posted 2 days ago
The Siren Hotel, an Ash Hotel

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Frequently asked questions

What's it like in Medical Center?
Travellers to the Medical Center neighbourhood in Detroit will be sure to enjoy their stay. Make sure that you visit Cultural Center Historic District and Lexus Velodrome as part of your Medical Center travel plans.
If I need to cancel my hotel reservation in Medical Center, will I receive a refund?
Yes, most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Medical Center.
What is there to do in this Detroit neighbourhood?
A few attractions you might want to check out while you're in Medical Center are Cultural Center Historic District and Lexus Velodrome. Ford Field and The Majestic Theatre are also worth a visit when you're out sightseeing in Detroit.