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Top hotels in Southeast Missouri
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is RM324 per night from 9 Jun to 10 Jun
RM324
per night
9 Jun - 10 Jun
7/10 Good! (1,004 reviews)
"The staff were all friendly and very helpful I brought my mother home to Sikeston for her 92nd Birthday and she got sick in the lobby and the staff helped me with her like she was their own Mom and for that I am forever grateful. I will always stay when you when I return home. Thank You"
Reviewed on 30 May 2024
Auburn Place Hotel And Suites
3265 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is RM328 per night from 10 Jun to 11 Jun
RM328
per night
10 Jun - 11 Jun
8.6/10 Excellent! (1,006 reviews)
"We have stayed here multiple times and each time has been good. The breakfast is always good. The staff we encounter is always nice. We have never had an issue. On our last visit, we forgot a bag in the room and the hotel called to let us know but we were unfortunately to far away to turn around ..."
Reviewed on 1 Jun 2024
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
The price is RM372 per night from 4 Jun to 5 Jun
RM372
per night
4 Jun - 5 Jun
8/10 Very Good! (1,002 reviews)
"Room was nice. Enjoyed talking with the other guests."
Reviewed on 1 Jun 2024
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit
Meramec Caverns
Explore the great outdoors at Meramec Caverns, a lovely green space in Sullivan. While in this family-friendly area, you can enjoy the cafes.
Elephant Rocks State Park
Explore the great outdoors at Elephant Rocks State Park, a lovely green space in Ironton. Make some time to visit the shops while you're in the area.
Ohio River
Commune with nature and explore the great outdoors at Ohio River during your travels in Valley Station. While you're in the area, wander around the parks.
What to do in Southeast Missouri
History Tour of Pythian Castle in Springfield Missouri
RM58
Per adult
80% of travellers recommend
Ozark Craft Beverage - Brewery Tour
RM478
Per adult
Explore Springfield with a Scavenger Hunt by Zombie Scavengers
RM93
Per adult
More trip options
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.