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Top hotels in Southeast Missouri
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is RM335 per night from 17 Jun to 18 Jun
RM335
per night
17 Jun - 18 Jun
7/10 Good! (1,002 reviews)
"Extremely quiet"
Reviewed on 13 Jun 2024
Auburn Place Hotel And Suites
3265 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is RM350 per night from 25 Jun to 26 Jun
RM350
per night
25 Jun - 26 Jun
8.6/10 Excellent! (1,004 reviews)
"great location, well run, clean and up to date"
Reviewed on 10 Jun 2024
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
The price is RM372 per night from 16 Jun to 17 Jun
RM372
per night
16 Jun - 17 Jun
8/10 Very Good! (1,000 reviews)
"Very clean and easy access"
Reviewed on 10 Jun 2024
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit
Meramec Caverns
Explore the great outdoors at Meramec Caverns, a lovely green space in Sullivan. While in this family-friendly area, you can enjoy the cafes.
Elephant Rocks State Park
Explore the great outdoors at Elephant Rocks State Park, a lovely green space in Ironton. Make some time to visit the shops while you're in the area.
Ohio River
Commune with nature and explore the great outdoors at Ohio River during your travels in Valley Station. While you're in the area, wander around the parks.
What to do in Southeast Missouri
History Tour of Pythian Castle in Springfield Missouri
RM58
Per adult
80% of travellers recommend
Ozark Craft Beverage - Brewery Tour
RM478
Per adult
Explore Springfield with a Scavenger Hunt by Zombie Scavengers
RM93
Per adult
More trip options
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.