A riverside promenade with cafes, trees, and buildings.

Santo Antonio hotels from RM310

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
28 Sept - 29 Sept
Tomorrow
29 Sept - 30 Sept
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Filter by

Star rating

Guest rating

Our top choices for Santo Antonio hotels

1. Olivia Lisboa Hotel 5*

Olivia Lisboa Hotel 5*
Lisbon City Center
United States
lakeesha
RM867
RM956 total
includes taxes & fees
6 Oct - 7 Oct
Olivia Lisboa Hotel 5*

2. EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel
Lisbon City Center
United Kingdom
Lisa
RM783
RM867 total
includes taxes & fees
3 Oct - 4 Oct
EPIC SANA Lisboa Hotel

3. Locke de Santa Joana

Locke de Santa Joana
Lisbon City Center
United Kingdom
Ian
RM525
RM594 total
includes taxes & fees
25 Oct - 26 Oct
Locke de Santa Joana

4. Hotel Vincci Liberdade

Hotel Vincci Liberdade
Lisbon City Center
United States
Jason
RM1,021
RM1,119 total
includes taxes & fees
4 Oct - 5 Oct
Hotel Vincci Liberdade

5. Dorma Liberdade

Dorma Liberdade
Lisbon City Center
United States
Ariagna
RM521
RM589 total
includes taxes & fees
4 Oct - 5 Oct
Dorma Liberdade

6. Marques De Pombal Hotel

Marques De Pombal Hotel
Lisbon City Center
Canada
Joanie
RM532
RM601 total
includes taxes & fees
27 Oct - 28 Oct
Marques De Pombal Hotel

7. Eurostars Das Letras

Eurostars Das Letras
Lisbon City Center
Canada
Lila
RM702
RM781 total
includes taxes & fees
28 Oct - 29 Oct
Eurostars Das Letras

8. HF Fénix Garden

HF Fénix Garden
Lisbon City Center
United States
Luisa
RM526
RM595 total
includes taxes & fees
24 Oct - 25 Oct
HF Fénix Garden

9. Heritage Lisboa Plaza Hotel - Avenida

Heritage Lisboa Plaza Hotel - Avenida
Lisbon City Center
United States
JOSE RAFAEL
RM936
RM1,030 total
includes taxes & fees
15 Oct - 16 Oct
Heritage Lisboa Plaza Hotel - Avenida

10. EPIC SANA Marques Hotel

EPIC SANA Marques Hotel
Lisbon City Center
United States
Anjelika
RM1,278
RM1,392 total
includes taxes & fees
18 Oct - 19 Oct
EPIC SANA Marques Hotel

11. Altis Grand Hotel

Altis Grand Hotel
Lisbon City Center
United Kingdom
Lisa
RM1,042
RM1,142 total
includes taxes & fees
5 Oct - 6 Oct
Altis Grand Hotel

12. Avani Avenida Liberdade Lisbon Hotel

Avani Avenida Liberdade Lisbon Hotel
Lisbon City Center
United States
Lazara
RM876
RM965 total
includes taxes & fees
29 Oct - 30 Oct
Avani Avenida Liberdade Lisbon Hotel

13. Casa Belmonte

Casa Belmonte
Lisbon City Center
Canada
Margaret
RM330
RM387 total
includes taxes & fees
13 Oct - 14 Oct
Casa Belmonte

14. PortoBay Liberdade

PortoBay Liberdade
Lisbon City Center
Canada
Martha
RM1,178
RM1,285 total
includes taxes & fees
28 Oct - 29 Oct
PortoBay Liberdade

15. H10 Duque de Loulé

H10 Duque de Loulé
Lisbon City Center
Australia
Juliet
RM701
RM780 total
includes taxes & fees
18 Oct - 19 Oct
H10 Duque de Loulé

16. HF Fénix Music

HF Fénix Music
Lisbon City Center
United Kingdom
paula
RM615
RM689 total
includes taxes & fees
25 Oct - 26 Oct
HF Fénix Music

17. Wilde Lisbon Liberdade

Wilde Lisbon Liberdade
Lisbon City Center
United States
Kimberly
RM729
RM810 total
includes taxes & fees
16 Oct - 17 Oct
Wilde Lisbon Liberdade

18. HF Fénix Lisboa

HF Fénix Lisboa
Lisbon City Center
United States
Sukanya
RM647
RM723 total
includes taxes & fees
29 Oct - 30 Oct
HF Fénix Lisboa

19. Mama Shelter Lisboa

Mama Shelter Lisboa
Lisbon City Center
United States
Yadira
RM639
RM714 total
includes taxes & fees
23 Oct - 24 Oct
Mama Shelter Lisboa

20. easyHotel Lisbon

easyHotel Lisbon
Lisbon City Center
Canada
Loc
RM350
RM408 total
includes taxes & fees
20 Oct - 21 Oct
easyHotel Lisbon
View all properties

Holiday Rentals in Santo Antonio

Aparthotel

Numa Lisbon Rato

Numa Lisbon Rato
Lisbon City Center
"Every was good."
Numa Lisbon Rato
Aparthotel

Altis Prime Hotel de Apartamentos

Altis Prime Hotel de Apartamentos
Lisbon City Center
"Great location, very spacious rooms, sleek modern design."
Altis Prime Hotel de Apartamentos
Apartment

LSA Liberdade by Numa

LSA Liberdade by Numa
Lisbon City Center
"Well located and great apartment for a short stay."
LSA Liberdade by Numa
Aparthotel

AZZULEA Avenida Apartments

AZZULEA Avenida Apartments
Lisbon City Center
"This exceeded my expectations! If you are looking to experience old world charm with all the modern amenities, this is it. Would highly recommend this stay!"
AZZULEA Avenida Apartments
Aparthotel

Limehome Lisbon Eca de Queiroz

Limehome Lisbon Eca de Queiroz
Lisbon City Center
"Everything we needed and more including a washing machine and drying rack. Beds were very comfortable."
Limehome Lisbon Eca de Queiroz
Apartment

Morgan-Jupiter Apartments

Morgan-Jupiter Apartments
Lisbon City Center
"Staff were really helpful and ready to help."
Morgan-Jupiter Apartments
Aparthotel

The Haus - Alegria

The Haus - Alegria
Lisbon City Center
"the best central location, clean and comfortable house "
The Haus - Alegria
Aparthotel

POSTCODE Liberdade

POSTCODE Liberdade
Lisbon City Center
"Perfect place for us. "
POSTCODE Liberdade
Apartment

LSA Príncipe Real by Numa

LSA Príncipe Real by Numa
Lisbon City Center
"Great location with a great park/ overlook right around the corner!"
LSA Príncipe Real by Numa
Aparthotel

BOULEVARD Boutique Studios

BOULEVARD Boutique Studios
Lisbon City Center
"Great location. Hospitality at its absolute best. "
BOULEVARD Boutique Studios
Aparthotel

LSA Avenida by Numa

LSA Avenida by Numa
Lisbon City Center
"Great location, parking can be hard"
LSA Avenida by Numa
Aparthotel

Altis Suites - Apartamentos Turísticos

Altis Suites - Apartamentos Turísticos
Lisbon City Center
"My family has repeatedly stay at this hotel for its ideal location. The hotel itself is a little old but very well maintained."
Altis Suites - Apartamentos Turísticos
Apartment

LSA Restauradores by Numa

LSA Restauradores by Numa
Lisbon City Center
"Clean and close to everything."
LSA Restauradores by Numa
Apartment

Marquês Best Apartments - Lisbon Best Apartments.

Marquês Best Apartments - Lisbon Best Apartments.
Lisbon City Center
"Beautiful apartment in very nice building with swimming pool walking distance to metro station. Would definitely stay here again."
Marquês Best Apartments - Lisbon Best Apartments.
Apartment

Spacious and Renovated Apartment With Amazing Patio, By TimeCooler

Spacious and Renovated Apartment With Amazing Patio, By TimeCooler
Lisbon City Center
"Shops nearby clean room great food and staff transportation"
Spacious and Renovated Apartment With Amazing Patio, By TimeCooler
See all holiday rentals
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santo Antonio attractions

A city square with a fountain, trees, and a building with 'SAO JOSE' signage.

Avenida da Liberdade

9.4/10 (3,467 reviews)
You can find the perfect gifts to bring home when you visit Avenida da Liberdade, a popular shopping spot in Santo Antonio. Discover the top-notch restaurants in this romantic area or seek out the local tours.
See properties
A modern building with a large glass facade, a blue awning, and a sign for 'Caixa Geral de Deposicao'.

Amoreiras Shopping Center

8.0/10 (225 reviews)
You can find the perfect gifts to bring home at Amoreiras Shopping Center during your trip to Campo de Ourique. Amble around this vibrant area's riverfront or experience its fascinating museums.
See properties
A pond surrounded by lush greenery and trees.

Botanical Garden

8.4/10 (800 reviews)
The oldest botanical garden in Portugal offers great views of the historic Tower of Belem and a peaceful place to rest away from the bustling city streets.
See properties
A fountain surrounded by trees, with a cityscape in the background.

Miradouro de São Pedro de Alcântara

8.8/10 (13 reviews)
You can learn about the history of Misericórdia with a trip to Miradouro de São Pedro de Alcântara. Amble around this vibrant area's riverfront or experience its fascinating museums.
See properties
A grand hall with high ceilings, large columns, and banners hanging from the ceiling.

National Museum of Natural History

8.6/10 (17 reviews)
Discover more about the geology of Portugal and the animals that once roamed here in this hands-on museum.
See properties
A street with a Michael Kors store and a Maria João Batista building.

Coracao de Jesus

9.4/10 (3 reviews)
You can find out about the history of Santo Antonio with a stop at Coracao de Jesus. Make time for the shops and local tours in this romantic area.
See properties

Cinemateca Portuguesa Museum

8.0/10 (3 reviews)
You can spend an afternoon exploring the galleries in Cinemateca Portuguesa Museum in Santo Antonio. Experience the acclaimed art galleries and fascinating museums in this family-friendly area.
See properties

Medeiros e Almeida Museum

8.8/10 (6 reviews)
You can spend an afternoon browsing the exhibits at Medeiros e Almeida Museum in Santo Antonio. Discover the top-notch restaurants and acclaimed art galleries in this romantic area.
See properties

Learn more about Santo Antonio

Wander through the elegant Avenida da Liberdade, where luxury shops line a boulevard flanked by beautiful gardens and historic squares. Take in panoramic city views at Miradouro de São Pedro de Alcântara before exploring the fascinating collections at the Medeiros e Almeida Museum.

See all hotels in Santo Antonio
A row of historic buildings with ornate balconies and detailed facades.

Top Santo Antonio Hotel Reviews

easyHotel Lisbon

easyHotel Lisbon

8/10 Good
"Very clean room, well-located near restaurants, the metro, and pedestrian streets, but extremely small—too small to fit two small suitcases."
Nancy 4-night trip
Posted 1 hour ago
easyHotel Lisbon
EPIC SANA Marques Hotel

EPIC SANA Marques Hotel

10/10 Excellent
"Céntrico, muy bien jubilado, limpio, buenas habitaciones.buen trato de los empleados, muy buenos café, es mi segunda vez en este hotel. Me encanta."
Yoletsys 4-night trip
Posted 1 hour ago
EPIC SANA Marques Hotel
Wilde Lisbon Liberdade

Wilde Lisbon Liberdade

10/10 Excellent
"Greta stay"
Alberto 3-night trip
Posted 2 hours ago
Wilde Lisbon Liberdade
Dorma Liberdade

Dorma Liberdade

8/10 Good
"Nice hotel."
Pryscila 2-night trip
Posted 4 hours ago
Dorma Liberdade
Lisboa Central Hostel

Lisboa Central Hostel

10/10 Excellent
"Great location"
Maritza 1-night trip
Posted 5 hours ago
Lisboa Central Hostel
Locke de Santa Joana

Locke de Santa Joana

10/10 Excellent
"Lovely hotel - centrally located with lovely amenities"
ophelia 5-night trip
Posted 6 hours ago
Locke de Santa Joana
Eurostars Das Letras

Eurostars Das Letras

10/10 Excellent
"Great friendly staff from check-in to check-out! Room was beautiful and clean! Close to attractions."
Suzanne 1-night trip
Posted 20 hours ago
Eurostars Das Letras
Pestana Lisboa Vintage City Center Suites

Pestana Lisboa Vintage City Center Suites

10/10 Excellent
"Great location and lovely room"
Fiona 3-night trip
Posted 21 hours ago
Pestana Lisboa Vintage City Center Suites
Numa Lisbon Rato

Numa Lisbon Rato

10/10 Excellent
"."
Marc 3-night trip
Posted 2 days ago
Numa Lisbon Rato

More cheap stays in Santo Antonio

Safestay Lisbon Bairro Alto

Safestay Lisbon Bairro Alto

Travessa do Fala Só, 9 Lisbon
RM269
RM322 total
29 Oct - 30 Oct
includes taxes & fees
7.8/10 Good! (76 reviews)
Safestay Lisbon Bairro Alto
Lisboa Central Hostel

Lisboa Central Hostel

Rua Rodrigues Sampaio n¦160 Lisbon
RM288
RM342 total
14 Oct - 15 Oct
includes taxes & fees
9.6/10 Exceptional! (333 reviews)
Lisboa Central Hostel
easyHotel Lisbon

easyHotel Lisbon

R. de Santa Marta 60 Lisbon
RM350
RM408 total
20 Oct - 21 Oct
includes taxes & fees
8.8/10 Excellent! (1,742 reviews)
easyHotel Lisbon
Hotel Dom Sancho I

Hotel Dom Sancho I

Avenida Liberdade 202, 2nd Floor Lisbon
RM355
RM413 total
18 Oct - 19 Oct
includes taxes & fees
7.8/10 Good! (1,004 reviews)
Hotel Dom Sancho I
ibis Lisboa Centro Liberdade

ibis Lisboa Centro Liberdade

Rua Barata Salgueiro 53 Lisbon
RM441
RM505 total
29 Oct - 30 Oct
includes taxes & fees
8.8/10 Excellent! (553 reviews)
ibis Lisboa Centro Liberdade
Limehome Lisbon Eca de Queiroz

Limehome Lisbon Eca de Queiroz

Rua Eça de Queiroz 4 Lisbon Lisboa
RM449
RM536 total
18 Oct - 19 Oct
includes taxes & fees
Limehome Lisbon Eca de Queiroz

Frequently asked questions

What's the best place to stay in Santo Antonio?
Based on our traveller data, Locke de Santa Joana is one of the top choices for your stay. This hotel is a short 3-minute walk from Avenida da Liberdade, and it offers 2 restaurants and 3 bars. Other good options for your trip include easyHotel Lisbon and Pestana Lisboa Vintage City Center Suites. See all available top hotels, or vacation rentals in Santo Antonio.
What are some of the best holiday rentals that Santo Antonio has to offer?
Lisbon Country Villa: This holiday home rental outside of Santo Antonio offers a terrace, a BBQ and a TV to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and kitchenware. See all vacation rentals in Santo Antonio.
If I need to cancel my hotel reservation in Santo Antonio, will I receive a refund?
Yes, the majority of hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santo Antonio.
What's the best budget-friendly hotel in Santo Antonio?
Based on reviews, easyHotel Lisbon is a popular hotel for our travellers who want a more economical choice, and features free Wi-Fi and air conditioning. Other choices to stay on the cheap include Safestay Lisbon Bairro Alto and Room Lisboa. View all budget hotels in Santo Antonio.
What's the best family accommodation in Santo Antonio?
EPIC SANA Lisboa Hotel is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your stay with the children include EPIC SANA Marques Hotel and 138 Liberdade Hotel. Also, children of all ages will enjoy a visit to National Museum of Natural History. Find more child-friendly accommodations in Santo Antonio.
What's the best LGBTQ-friendly accommodation in Santo Antonio?
Locke de Santa Joana is a top LGBTQ-friendly hotel, and features 2 restaurants and Smart TVs. EPIC SANA Lisboa Hotel and EPIC SANA Marques Hotel are two other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santo Antonio.
What's the best dog-friendly accommodation option in Santo Antonio?
Locke de Santa Joana is a top hotel for people travelling with their pets, and offers 2 restaurants and a seasonal outdoor pool for its human guests. Other good options for you and your pet include Pestana Lisboa Vintage City Center Suites and Hotel Lisboa Plaza, a Lisbon Heritage Collection. See more pet-friendly hotel accommodations in Santo Antonio.
What's the best high-end place to stay in Santo Antonio?
Olivia Lisboa Hotel 5* is a luxury hotel with a restaurant, and a popular choice for Expedia travellers looking for an elegant place to stay. EPIC SANA Lisboa Hotel and EPIC SANA Marques Hotel are two other upscale options for your stay. Find more luxury hotels in Santo Antonio.
What's the best boutique hotel in Santo Antonio?
Hotel Lisboa Plaza, a Lisbon Heritage Collection is a favourite hotel with Expedia travellers looking for a stylish stay, and features a rooftop terrace and a fitness centre. 138 Liberdade Hotel and Eurostars Das Letras are other choices for a boutique stay. See all boutique hotels in Santo Antonio.
What are some accommodation options with pools in Santo Antonio?
EPIC SANA Lisboa Hotel is a top hotel with a seasonal outdoor pool, an indoor pool and a full-service spa. A couple of other options that offer an on-site pool include EPIC SANA Marques Hotel and Altis Grand Hotel. View all hotels with pools in Santo Antonio.
What is the best spa hotel in Santo Antonio?
EPIC SANA Lisboa Hotel is a top luxury spa hotel featuring a pool, a rooftop terrace, a 24-hour fitness centre and a hair salon. Treat yourself to a facial, body scrub or deep-tissue massage at SAYANNA Wellness & SPA. Other popular spa hotels in Santo Antonio include EPIC SANA Marques Hotel and Altis Grand Hotel. See all spa hotels in Santo Antonio.
What is staying in Santo Antonio like?
Luxury-minded travellers will find upscale places to stay in Santo Antonio, and visitors give high marks for the renowned art and relaxing spas. Welcoming and urban, this city also attracts tourists with its gardens. Top sights around the area include Avenida da Liberdade and Rossio Square. In Santo Antonio, there are 683 hotels and other accommodation options to choose from. Find out more about Santo Antonio.
What should I do while I'm visiting Santo Antonio?
Known for its art scene, cultural venues include Cinemateca Portuguesa Museum, Medeiros e Almeida Museum and National Museum of Natural History. Landmarks like Coracao de Jesus, Marquis of Pombal Square and São José might be worth a visit. Avenida da Liberdade is another notable sight to explore. Take a look at what more there is to see and do in Expedia's Santo Antonio guide.
How should I get around Santo Antonio?
Walk to nearby metro stations such as Avenida Station, Marques de Pombal Station and Rato Station. If you want to venture out around the area, you may want a rental car in Santo Antonio for your journey.
What's the seasonal weather in Santo Antonio?
The hottest months are usually August and July, with an average temperature of 21°C, while the coldest months are February and January, with an average of 13°C. Average annual precipitation for Santo Antonio is 573 mm.