Top Motels in Cape Girardeau County in 2026

A rocky stream surrounded by trees and foliage.

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Our top choices for Cape Girardeau County motels

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

1. Super 8 by Wyndham Perryville

Perryville

Matthew

RM318 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

2. Town House Inn Cape Giradreau

Cape Girardeau

Hope

RM334 total

includes taxes & fees

14 Oct - 15 Oct

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

3. Town House Inn

Jackson

Taylor

RM315 total

includes taxes & fees

14 Oct - 15 Oct

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Top Cape Girardeau County Hotel Reviews

Drury Inn & Suites Jackson MO

8/10 Good

"My room was spacious. The staff was amazing. Everything was well kept and maintained. I didn't like that the toilet in my king deluxe room was very short (low). I'm 5' 4" and husband is 6'. I struggled getting up. I'm sure my husband was very uncomfortable as well! Also, the placement of the luggage carts just beyond the entry doors and registration placed immediately left of same doors with a line of standing people seems like a fire hazard and very inconvenient. I struggled to get pass the area with my loaded luggage cart while avoiding empty luggage carts and nearly colliding with an older gentleman."