A cannon on a brick platform by a river, with a steamboat in the background.

New Madrid hotels from RM196

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Check prices for these dates

Tonight
20 Oct - 21 Oct
Tomorrow
21 Oct - 22 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

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Our top choices for New Madrid hotels

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.
A room with a brown leather sofa, a red chair, and a cityscape painting on the wall.
A hotel with a central entrance, multiple parking spaces, and a well-lit facade.
A modern kitchen with a built-in microwave, a black refrigerator, and a wooden countertop.

1. Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
Marston
United States
Brenda
RM228
RM261 total
includes taxes & fees
25 Oct - 26 Oct
Super 8 By Wyndham Marston
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

2. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
Lori
RM430
RM489 total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn Sikeston
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

3. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Roslyn
RM412
RM469 total
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites by Marriott Sikeston
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A kitchenette with a coffee machine, a kettle, and storage shelves.
A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.
A breakfast buffet counter with a bakery section and a display for breakfast items.

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
Melissa
RM396
RM450 total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Sikeston Southwest by IHG
Property amenity
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

5. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
United States
Rubin
RM445
RM506 total
includes taxes & fees
29 Oct - 30 Oct
TownePlace Suites by Marriott Sikeston
A hotel lobby with a glass table and checkered chairs, an exit door, and a vending machine.
A bathroom with a sink, mirror, and chair.
A hotel room with a bed, a desk, a television, and a seating area with a small table.
A hotel room with two beds, a television, a desk, and a mirror.

6. Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
Marston
United States
Frank
RM157
RM196 total
includes taxes & fees
21 Oct - 22 Oct
Travel Inn Marston I-55 by Hotel O
A hotel room with a dark wooden desk, a television, a lamp, a chair, and a mirror on the wall.
A parking lot with a grassy area and trees in the background.
A building with multiple floors and a flat roof, surrounded by a grassy area with trees.
A bathroom with a bathtub, a toilet, and a sink.

7. Reelfoot Lake Inn

Reelfoot Lake Inn
Tiptonville
United States
Danny
RM249
RM286 total
includes taxes & fees
1 Nov - 2 Nov
Reelfoot Lake Inn
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Stay near popular New Madrid attractions

New Madrid Historical Museum

8.2/10 (36 reviews)
Explore the powerful 1811-1812 earthquakes that reshaped America's heartland at this historic museum. Engage with knowledgeable curators while viewing artefacts from Native American cultures and the Civil War.
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Hunter-Dawson State Historic Site

7.6/10 (13 reviews)
Step back in time at this antebellum mansion with 80% of its original furnishings intact. Explore nine fireplaces and period decor through guided tours of the 15-room Hunter-Dawson House.
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River Ridge Winery

8.4/10 (15 reviews)
Sip handcrafted wines in a century-old farmhouse atop the Mississippi River hills. Wander through estate vineyards or enjoy fresh meals on the scenic grounds of this Missouri wine destination.
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Learn more about New Madrid

The New Madrid Historical Museum reveals the dramatic storey of the 1811-1812 earthquakes that changed the course of the Mississippi River. Enjoy peaceful fishing at Donaldson Point Conservation Area or take a sunset river cruise to spot bald eagles along the mighty Mississippi.

See all hotels in New Madrid
A cannon on a brick platform by a river, with a steamboat in the background.

Top New Madrid Hotel Reviews

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

8/10 Good
"Got there late and staff was very helpful. Room was clean and comfortable"
Wendy 1-night trip
Posted 20 hours ago
Super 8 By Wyndham Marston
Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"Every part of this stay was excellent, from check in to check out. Helpful and friendly staff, wonderful, clean and well furnished room, delicious breakfast. Highly recommend."
Carol 1-night trip
Posted 1 day ago
Hampton Inn Sikeston
Reelfoot Lake Inn

Reelfoot Lake Inn

8/10 Good
"Dated but descent."
Lisa 1-night trip
Posted 10 days ago
Reelfoot Lake Inn
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent
"Clean, comfortable room. Nice staff and good breakfast choices."
Antoinette 1-night trip
Posted 11 days ago
Holiday Inn Express & Suites Sikeston Southwest by IHG
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

10/10 Excellent
"My overall experience was amazing from the time I checked in until I left. The staff were super pleasant and incredible. My room was clean and spacious. I never been in an extended stay room before. I definitely will be booking a suite like this one again."
Stacy 2-night trip
Posted 1 month ago
TownePlace Suites by Marriott Sikeston
Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O

8/10 Good
"Worked for the price. Room was clean. Staff was friendly! "
Alicia 1-night trip
Posted 6 months ago
Travel Inn Marston I-55 by Hotel O

More cheap stays in New Madrid

Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O

301 Route Ad Marston MO
RM157
RM196 total
21 Oct - 22 Oct
includes taxes & fees
5.8/10 (129 reviews)
Travel Inn Marston I-55 by Hotel O
Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

501 S Outer Road Marston MO
RM228
RM261 total
25 Oct - 26 Oct
includes taxes & fees
8/10 Very good! (80 reviews)
Super 8 By Wyndham Marston
Reelfoot Lake Inn

Reelfoot Lake Inn

1520 State Route 21 East Tiptonville TN
RM249
RM286 total
1 Nov - 2 Nov
includes taxes & fees
7.2/10 Good! (515 reviews)
Reelfoot Lake Inn
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO
RM396
RM450 total
8 Nov - 9 Nov
includes taxes & fees
8.8/10 Excellent! (517 reviews)
Holiday Inn Express & Suites Sikeston Southwest by IHG
Hampton Inn Sikeston

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO
RM430
RM489 total
1 Nov - 2 Nov
includes taxes & fees
9/10 Wonderful! (646 reviews)
Hampton Inn Sikeston
New Orleans Inn Portageville

New Orleans Inn Portageville

600 US-61 Portageville MO
Get rates
8/10 Very good! (799 reviews)
New Orleans Inn Portageville

Frequently asked questions

Where is the best place for a stay in New Madrid?
Hampton Inn Sikeston, located 18.9 mi (30.4 km) from the heart of New Madrid, is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are New Orleans Inn Portageville and Fairfield Inn & Suites by Marriott Sikeston. See all available top hotels, or vacation rentals in New Madrid.
If I need to cancel my hotel reservation in New Madrid, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in New Madrid.
What is staying in New Madrid like?
Visitors can enjoy all that New Madrid has to offer, including the parks and museums. There are 57 hotels and other accommodation options in the surrounding area. Find out more about New Madrid.
What should I do while I'm visiting New Madrid?
Cultural venues include New Madrid Historical Museum and Hunter-Dawson State Historic Site. A couple of additional sights to add to your itinerary are Mississippi River and River Ridge Winery. Take a look at what more there is to see and do in Expedia's New Madrid guide.
What's the seasonal weather in New Madrid?
The hottest months are usually July and August, with an average temperature of 25ยฐC, while the coldest months are January and February, with an average of 6ยฐC. Average annual precipitation for New Madrid is 1537 mm.

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