Serra Mesa

San Diego

Aerial view of house in Serra Mesa City in San Diego, California, USA. Green Dry Valley and Villas
Aerial view of house in Serra Mesa City in San Diego, California, USA. Green Dry Valley and Villas

Popular places to visit

Things to do


Top hotels in Serra Mesa

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is RM782 per night from 5 Apr to 6 Apr
RM782
RM1,108 total
5 Apr - 6 Apr
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.8/10 Excellent! (2,447 reviews)
Could be a really amazing resort, in need of a face lift. The main restaurant was closed on M/T and not open until 5pm Wednesday evening which was unfortunate as our stay was M-W. Hidden costs tacked onto Expedia's cost that is supposed to be inclusive of taxes and fees. And on top of that, they ...

Reviewed on 5 Mar 2026

Paradise Point Resort & Spa
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
The price is RM519 per night from 11 Mar to 12 Mar
RM519
RM597 total
11 Mar - 12 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, a marina and a health club. Our guests praise the breakfast and the restaurant in their ...
9.2/10 Wonderful! (3,455 reviews)
It was great to see the water filter and the free morning coffee downstairs. Awesome location, beautiful views and comfortable rooms. Loved it!

Reviewed on 5 Mar 2026

Bay Club Hotel & Marina
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is RM892 per night from 11 Mar to 12 Mar
RM892
RM1,225 total
11 Mar - 12 Mar
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and a nightclub. Our guests praise the helpful staff and the convenient parking in their reviews. ...
9/10 Wonderful! (3,375 reviews)
Pool area was great, kids splashing around the hot tub was a little annoying. Had a giant cockroach in or stack of hand towels in our bathroom but other than that it was a great time and great location

Reviewed on 6 Mar 2026

Hard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
The price is RM479 per night from 5 Apr to 6 Apr
RM479
RM555 total
5 Apr - 6 Apr
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
9/10 Wonderful! (1,160 reviews)
Came in and check in was a breeze. The room was Clean and had a great view of the city. couldn’t have ask for more, room was 1206

Reviewed on 5 Mar 2026

The DEXTRO Little Italy, BW Premier Collection
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is RM287 per night from 12 Mar to 13 Mar
RM287
RM330 total
12 Mar - 13 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, free parking and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. ...
8/10 Very Good! (3,261 reviews)
I love this hotel! The staff is so kind and efficient! The rooms are clean, the bed is comfy. The rooms are basic and I like it that way! The price is perfect. I will always stay here while in San Diego.

Reviewed on 5 Mar 2026

Best Western Seven Seas
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
The price is RM370 per night from 8 Mar to 9 Mar
RM370
RM425 total
8 Mar - 9 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, a fitness centre and parking (surcharge). Our guests praise the helpful staff and the clean ...
8/10 Very Good! (2,533 reviews)
I enjoyed my stay

Reviewed on 6 Mar 2026

Days Inn by Wyndham San Diego Hotel Circle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Serra Mesa

Closeup of the Adobe walls of the historic Mission De Alcala San Diego California

Mission Valley

4/5(36 area reviews)

Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Mission Valley Mall and Fashion Valley Mall, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.

Mission Valley
SanDiego_NorthPark_6346499_001

North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park
Gossip Grill

Hillcrest

5/5(1 area review)

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest
I didn’t go in as I felt the outside was pretty great already. Good area of town for a self-guided walking tour.

Old Town San Diego

4/5(5 area reviews)

The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.

Old Town San Diego
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Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Mission Bay
Little Italy

Little Italy

Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.

Little Italy


Serra Mesa

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