A residential area with houses, roads, and a hilly landscape.

Hotels in Serra Mesa, San Diego

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Our top choices for Serra Mesa hotels

1. Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
6.4 km from Serra Mesa
8.4 out of 10, Very good, (1,009 reviews)
"great stay"
United States
David
The price is RM515
RM594 total
includes taxes & fees
27 Jul - 28 Jul
Crowne Plaza San Diego - Mission Valley by IHG

2. Valli Hi Motel

Valli Hi Motel
2.5 star property
28.3 km from Serra Mesa
8.4 out of 10, Very good, (1,024 reviews)
"Great place to stay."
United States
Allan
The price is RM368
RM419 total
includes taxes & fees
30 Jun - 1 Jul
Valli Hi Motel

3. La Quinta Inn by Wyndham San Diego - Miramar

La Quinta Inn by Wyndham San Diego - Miramar
3.0 star property
16.7 km from Serra Mesa
8.0 out of 10, Very good, (1,336 reviews)
"Clean rooms, helpful staff and great breakfast."
United States
isabel
The price is RM552
RM634 total
includes taxes & fees
5 Jul - 6 Jul
La Quinta Inn by Wyndham San Diego - Miramar

4. Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
10.1 km from Serra Mesa
8.4 out of 10, Very good, (3,543 reviews)
"Great location and shuttle service to and from the airport."
Canada
Malinda
The price is RM609
RM907 total
includes taxes & fees
5 Jul - 6 Jul
Sheraton San Diego Resort

5. Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.8 km from Serra Mesa
9.4 out of 10, Exceptional, (1,992 reviews)
"Always a great stay"
United States
Jeanette
The price is RM473
RM569 total
includes taxes & fees
12 Jul - 13 Jul
Sycuan Casino Resort

6. Best Western Americana Inn

Best Western Americana Inn
2.5 star property
28.1 km from Serra Mesa
8.8 out of 10, Excellent, (1,316 reviews)
"The breakfast was great, the staff was helpful, and the room was clean and spacious!"
United States
Christopher
The price is RM500
RM569 total
includes taxes & fees
5 Jul - 6 Jul
Best Western Americana Inn

7. Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
7.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,082 reviews)
"Staff was so great nice rooms really great stay"
United States
Amelia
The price is RM589
RM677 total
includes taxes & fees
1 Jul - 2 Jul
Holiday Inn Express San Diego Airport - Old Town by IHG

8. Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,175 reviews)
"Clean room, staff was very helpful, parking was easy and accessible!"
United States
Hector
The price is RM527
RM606 total
includes taxes & fees
1 Jul - 2 Jul
Wyndham Garden San Diego Near SeaWorld

9. Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
5.3 km from Serra Mesa
9.4 out of 10, Exceptional, (1,758 reviews)
"Beautiful hotel"
United States
Cuauhtemoc
The price is RM1,059
RM1,217 total
includes taxes & fees
30 Jun - 1 Jul
Lafayette Hotel & Club

10. Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
9.9 km from Serra Mesa
8.4 out of 10, Very good, (6,251 reviews)
"Great place to stay if visiting san diego recommend"
United States
Carlos
The price is RM622
RM864 total
includes taxes & fees
6 Jul - 7 Jul
Wyndham San Diego Bayside

11. GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (2,201 reviews)
"THE BED WAS SO SOFT ROOM WAS SO CLEAN BREAKFAST WAS GREAT AND THE PRICE WAS KILLER FOR THE LOCATION really a great place to stay"
United States
Tyson
The price is RM484
RM557 total
includes taxes & fees
6 Jul - 7 Jul
GreenTree Inn San Diego Mission Bay

12. Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3,896 reviews)
"Great stay"
United States
Cameron
The price is RM650
RM716 total
includes taxes & fees
30 Jun - 1 Jul
Best Western Plus Marina Gateway Hotel

13. Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
Old Town San Diego, 7.4 km from Serra Mesa
8.8 out of 10, Excellent, (1,471 reviews)
"Hotel is lovely mission style in keeping with the area. The location is very convenient to local attractions."
United States
Toni
The price is RM726
RM835 total
includes taxes & fees
1 Jul - 2 Jul
Hilton Garden Inn San Diego Old Town/SeaWorld Area

14. Courtyard by Marriott San Diego Airport/Liberty Station

Courtyard by Marriott San Diego Airport/Liberty Station
3.0 star property
10.7 km from Serra Mesa
9.2 out of 10, Wonderful, (1,295 reviews)
"Was a lovely stay and it overlooks the water."
United States
Kara
The price is RM761
RM874 total
includes taxes & fees
7 Jul - 8 Jul
Courtyard by Marriott San Diego Airport/Liberty Station

15. Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
11.1 km from Serra Mesa
8.6 out of 10, Excellent, (2,180 reviews)
"The rooms were very clean and the view was beautiful!"
United States
Makaya
The price is RM803
RM1,131 total
includes taxes & fees
1 Jul - 2 Jul
Hilton San Diego Bayfront

16. Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
18.5 km from Serra Mesa
9.4 out of 10, Exceptional, (1,264 reviews)
"We had a very wonderful time at our stay here"
United States
Liezl
The price is RM726
RM799 total
includes taxes & fees
5 Jul - 6 Jul
Holiday Inn Express San Diego South - Chula Vista by IHG

17. Pleasant Inn

Pleasant Inn
2.5 star property
4.8 km from Serra Mesa
8.6 out of 10, Excellent, (1,462 reviews)
"Staff were very accommodating & friendly the room was clean i would stay there again!"
United States
Scott
The price is RM443
RM508 total
includes taxes & fees
19 Jul - 20 Jul
Pleasant Inn

18. Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
8.2 km from Serra Mesa
8.6 out of 10, Excellent, (3,823 reviews)
"The location of the hotel is convenient repertory people who want to visit Seaworld."
United States
Bektursun
The price is RM544
RM625 total
includes taxes & fees
1 Jul - 2 Jul
Comfort Inn Sea World Area

19. Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
9.1 km from Serra Mesa
7.2 out of 10, Good, (1,573 reviews)
"Great stay"
United States
Alyssa
The price is RM286
RM329 total
includes taxes & fees
5 Jul - 6 Jul
Heritage Inn San Diego

20. Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
10.6 km from Serra Mesa
9.2 out of 10, Wonderful, (1,706 reviews)
"Good location, clean room and nice staff. A great place to stay."
United States
Patricia
The price is RM701
RM805 total
includes taxes & fees
19 Jul - 20 Jul
Hampton Inn & Suites San Diego Airport Liberty Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most. Learn more about Serra Mesa
Learn more about Serra Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 39 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Snapdragon Stadium and Sharp Learning Resource Center are also worth a stop.

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