Hotels in Serra Mesa, San Diego

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels in Serra Mesa, San Diego

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1341)
"I enjoyed the location and the pool area."
Sycuan Casino Resort

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1001)
"Great place!"
The price is RM492
RM542 total
includes taxes & fees
29 Jun - 30 Jun
Days Inn by Wyndham San Diego-East/El Cajon

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.6 out of 10, Good, (1001)
"Nice staff and quiet "
The price is RM400
RM440 total
includes taxes & fees
29 Jun - 30 Jun
Super 8 by Wyndham El Cajon/San Diego

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very good, (1002)
"Stayed here while visiting friends, best in the area and very comfortable. "
The price is RM522
RM574 total
includes taxes & fees
6 Jul - 7 Jul
Best Western Plus La Mesa San Diego

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.4 out of 10, Exceptional, (355)
"Great spot for business travelers "
The price is RM907
RM999 total
includes taxes & fees
30 Jun - 1 Jul
SpringHill Suites by Marriott Chula Vista Eastlake

Ramada by Wyndham San Diego Poway Miramar

2.0 star property
6.8 out of 10, (819)
"Great for a quick night stay"
The price is RM419
RM460 total
includes taxes & fees
29 Jun - 30 Jun
Ramada by Wyndham San Diego Poway Miramar

Sonesta ES Suites San Diego - Rancho Bernardo

3.0 star property
8.4 out of 10, Very good, (1008)
"Very nice place for families "
The price is RM644
RM734 total
includes taxes & fees
1 Jul - 2 Jul
Sonesta ES Suites San Diego - Rancho Bernardo

Sonesta ES Suites Carmel Mountain – San Diego

3.0 star property
8.4 out of 10, Very good, (900)
"Well maintained with friendly staff. Great location with easy access & lot of eateries & shopping places around. "
The price is RM826
RM941 total
includes taxes & fees
13 Jul - 14 Jul
Sonesta ES Suites Carmel Mountain – San Diego

Heritage Inn La Mesa

2.0 star property
6.6 out of 10, (1005)
"Small rooms but friendly staff and prime location"
The price is RM305
RM336 total
includes taxes & fees
29 Jun - 30 Jun
Heritage Inn La Mesa

La Quinta Inn by Wyndham San Diego - Miramar

3.0 star property
7.4 out of 10, Good, (1001)
"We enjoyed our stay. The breakfast was not what we expected but we appreciated the stay."
The price is RM468
RM538 total
includes taxes & fees
13 Jul - 14 Jul
La Quinta Inn by Wyndham San Diego - Miramar

Lamplighter Inn & Suites at SDSU

2.5 star property
9.2 out of 10, Wonderful, (1173)
"Nice place to stay "
Lamplighter Inn & Suites at SDSU

Best Western San Diego/Miramar Hotel

2.5 star property
7.8 out of 10, Good, (1044)
"Great stay"
The price is RM616
RM708 total
includes taxes & fees
6 Jul - 7 Jul
Best Western San Diego/Miramar Hotel

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1437)
"Good breakfast, close to concert venue, easy freeway access "
The price is RM537
RM590 total
includes taxes & fees
2 Jul - 3 Jul
Best Western Chula Vista/Otay Valley Hotel

Valli Hi Motel

2.5 star property
8.2 out of 10, Very good, (1001)
"Affordable and near the border for convenience. "
Valli Hi Motel

Best Western Americana Inn

2.5 star property
8.8 out of 10, Excellent, (1104)
"We really enjoy this hotel, it was clean and the service was excellent."
The price is RM518
RM590 total
includes taxes & fees
2 Jul - 3 Jul
Best Western Americana Inn

Chula Vista Inn

2.5 star property
6.6 out of 10, (1000)
"Nice hotel "
Chula Vista Inn

Quality Inn San Diego South - Chula Vista

2.5 star property
7.8 out of 10, Good, (968)
"Easy to get to, affordable and clean "
The price is RM530
RM583 total
includes taxes & fees
6 Jul - 7 Jul
Quality Inn San Diego South - Chula Vista

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1734)
"Great rooms ,Awesome staff. And pet friendly!!! "
The price is RM288
RM317 total
includes taxes & fees
29 Jun - 30 Jun
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1191)
"Excellent staff willing to assist and help with any questions. Most comfortable stay, I will definitely be back. "
The price is RM601
RM663 total
includes taxes & fees
6 Jul - 7 Jul
Hercor Hotel - Urban Boutique

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.2 out of 10, Good, (1000)
"Enjoyed our stay"
The price is RM504
RM556 total
includes taxes & fees
29 Jun - 30 Jun
Howard Johnson by Wyndham National City/San Diego South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most. Learn more about Serra Mesa
Learn more about Serra Mesa
Downtown San Diego map

Downtown San Diego

1 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Seaport Village and Petco Park are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter map

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach map

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Ocean Beach.

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels can I expect to find in the Serra Mesa area?

Expedia has 35 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.

What can I see and do in this San Diego neighbourhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.