Hotels in Serra Mesa, San Diego

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Our top choices for Serra Mesa hotels

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.8 km from Serra Mesa
9.4 out of 10, Exceptional, (1,876 reviews)
"Amazing rooms and casino "
United States
Bryan
The price is RM390
RM476 total
includes taxes & fees
4 May - 5 May
Sycuan Casino Resort

Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego
2.5 star property
14 km from Serra Mesa
8.4 out of 10, Very good, (1,002 reviews)
"Clean room, clean property, kind staff, great breakfast, very spacious rooms."
United States
Sergio
The price is RM504
RM554 total
includes taxes & fees
10 May - 11 May
Best Western Plus La Mesa San Diego

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
28.1 km from Serra Mesa
9.0 out of 10, Wonderful, (1,263 reviews)
"Clean room, nice staff, a simple breakfast, and free parking on site."
United States
Nicole
The price is RM483
RM550 total
includes taxes & fees
12 May - 13 May
Best Western Americana Inn

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
10.6 km from Serra Mesa
9.2 out of 10, Wonderful, (1,713 reviews)
"Great location, clean room plus friendly staffes."
United States
Alfred
The price is RM669
RM768 total
includes taxes & fees
10 May - 11 May
Hampton Inn & Suites San Diego Airport Liberty Station

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
18.7 km from Serra Mesa
8.6 out of 10, Excellent, (1,602 reviews)
"Staff was friendly, and breakfast was excellent"
United States
Royce
The price is RM423
RM466 total
includes taxes & fees
19 May - 20 May
La Quinta Inn by Wyndham San Diego Chula Vista

Studio 6 Suites San Ysidro, CA -San Diego South Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay
2.5 star property
29.4 km from Serra Mesa
8.0 out of 10, Very good, (1,620 reviews)
"Clean room, friendly and nice staff, easy parking and safe "
United States
Erik
The price is RM316
RM360 total
includes taxes & fees
3 May - 4 May
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Ramada by Wyndham San Diego Poway Miramar

Ramada by Wyndham San Diego Poway Miramar
2.0 star property
18.2 km from Serra Mesa
7.0 out of 10, Good, (1,009 reviews)
"Quick to checking in nice staff and breakfast was good there was plenty of parking lot to park"
United States
Ruffa Regina
The price is RM359
RM395 total
includes taxes & fees
30 Apr - 1 May
Ramada by Wyndham San Diego Poway Miramar

Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA
3.0 star property
11.7 km from Serra Mesa
9.0 out of 10, Wonderful, (1,469 reviews)
"Breakfast was very good."
United States
Richard
The price is RM635
RM729 total
includes taxes & fees
3 May - 4 May
Country Inn & Suites by Radisson, San Diego North, CA

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
7.9 km from Serra Mesa
9.0 out of 10, Wonderful, (1,066 reviews)
"It was clean and convenient to the airport."
United States
Joey L
The price is RM557
RM641 total
includes taxes & fees
5 May - 6 May
Holiday Inn Express San Diego Airport - Old Town by IHG

Courtyard by Marriott San Diego El Cajon

Courtyard by Marriott San Diego El Cajon
3.0 star property
16.6 km from Serra Mesa
9.2 out of 10, Wonderful, (1,000 reviews)
"Really nice staff and great hotel!"
Canada
Shana
The price is RM628
RM693 total
includes taxes & fees
3 May - 4 May
Courtyard by Marriott San Diego El Cajon

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
10.1 km from Serra Mesa
8.4 out of 10, Very good, (3,498 reviews)
"Great stay and family friendly "
United States
Gregory
The price is RM668
RM968 total
includes taxes & fees
3 May - 4 May
Sheraton San Diego Resort

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3,812 reviews)
"The room was clean, staff was really friendly and helpful, there is plenty of parking spots. I would definitely stay again in this hotel "
United States
Jessica
The price is RM601
RM663 total
includes taxes & fees
10 May - 11 May
Best Western Plus Marina Gateway Hotel

Pleasant Inn

Pleasant Inn
2.5 star property
4.8 km from Serra Mesa
8.6 out of 10, Excellent, (1,378 reviews)
" Clean room friendly staff"
Canada
Laurent
The price is RM370
RM424 total
includes taxes & fees
11 May - 12 May
Pleasant Inn

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,211 reviews)
"Room was clean hotel was close to beach & restaurant "
United States
Andrea
The price is RM431
RM495 total
includes taxes & fees
30 Apr - 1 May
Wyndham Garden San Diego Near SeaWorld

Lamplighter Inn & Suites at SDSU

Lamplighter Inn & Suites at SDSU
2.5 star property
8.4 km from Serra Mesa
9.0 out of 10, Wonderful, (1,410 reviews)
"Clean room, beautiful landscaping, adequate breakfast, easy parking. "
United States
Deborah
The price is RM612
RM690 total
includes taxes & fees
18 May - 19 May
Lamplighter Inn & Suites at SDSU

California Suites Hotel

California Suites Hotel
2.0 star property
4.8 km from Serra Mesa
7.8 out of 10, Good, (2,508 reviews)
"Very comfortable, nice pool and hot tub, quiet, pretty location, and close to lots of stuff! Would stay here again! "
United States
Stephon
The price is RM317
RM363 total
includes taxes & fees
3 May - 4 May
California Suites Hotel

Best Western Seven Seas

Best Western Seven Seas
3.0 star property
5.3 km from Serra Mesa
7.8 out of 10, Good, (3,431 reviews)
"For a family of 4, the amenities and location were excellent! Very close to many attractions but also perfect for anyone who wants to stay on site!"
United States
Adriana
The price is RM324
RM372 total
includes taxes & fees
3 May - 4 May
Best Western Seven Seas

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
9.1 km from Serra Mesa
7.4 out of 10, Good, (1,411 reviews)
"Clean room, decent parking, and close to the beach "
United States
Curtis
The price is RM279
RM321 total
includes taxes & fees
5 May - 6 May
Heritage Inn San Diego

Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
18.5 km from Serra Mesa
9.4 out of 10, Exceptional, (1,113 reviews)
"Great hotel and breakfast "
United States
Sankara
The price is RM531
RM584 total
includes taxes & fees
10 May - 11 May
Holiday Inn Express San Diego South - Chula Vista by IHG

Courtyard by Marriott San Diego Central

Courtyard by Marriott San Diego Central
3.0 star property
2.6 km from Serra Mesa
8.8 out of 10, Excellent, (1,007 reviews)
"We enjoyed our stay. Premises were very clean, staff was very friendly, beds were clean and very comfortable, my family and I really enjoyed the pool, we will be back! "
Mexico
Chantal Rocio
The price is RM558
RM641 total
includes taxes & fees
26 May - 27 May
Courtyard by Marriott San Diego Central
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most. Learn more about Serra Mesa
Learn more about Serra Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 38 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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