Serra Mesa
San Diego
Visit Serra Mesa
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's acclaimed art galleries and entertainment choices.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Balboa Park
One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Things to do
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
Speed Boat Adventure Tour: Thrills on the San Diego Bay
San Diego: Unlimited Ride & Play Pass at Belmont Park
Private Surf Lesson Solana Beach Ride the Waves Fletcher Cove 2hr
Top hotels in Serra Mesa
Hotel del Coronado, Curio Collection by Hilton
Room was nice, walkability was great. On site amenities made the stay easy traveling with a toddler.
Reviewed on 18 Nov 2025
Legacy Resort Hotel & Spa
Great food, clean rooms
Reviewed on 25 Nov 2025
Hampton Inn & Suites by Hilton San Diego SeaWorld
The location.
Reviewed on 26 Nov 2025
Hard Rock Hotel San Diego
Required an accumulated deposit for all the nights there, in advance of the stay. For example, if the deposit for each night was $100 and the stay was 5 nights, $500 was secured. This, on a prepayed hotel room. I had booked this room for an adult child (over 30 years old) as a gift and found this ...
Reviewed on 26 Nov 2025
Manchester Grand Hyatt San Diego
Great place, need to improve the rooms !
Reviewed on 24 Nov 2025
The DEXTRO Little Italy, BW Premier Collection
Mostly everything was great but the a/c wall unit was controlled by the wall thermostat but no matter what temp you set it at or even turn it off it runs 24/7, making the room like a refrigerator
Reviewed on 1 Dec 2025
Other neighbourhoods around Serra Mesa
Mission Valley
Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Mission Valley Mall and Fashion Valley Mall, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Del Cerro
While there might not be top attractions in Del Cerro, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.
Old Town San Diego
The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.
Mid-City
While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.
Serra Mesa
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