Serra Mesa
San Diego
Visit Serra Mesa
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's entertainment choices and fascinating museums.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Things to do
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
San Diego: Museum of Illusions Entry Ticket
San Diego Whale Watching & Dolphin Cruise
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
Maritime Museum of San Diego Admission Ticket
Top hotels in Serra Mesa
Paradise Point Resort & Spa
Food was overpriced and not very good across the board. Gouged for parking. Not worth the cost.
Reviewed on 3 Mar 2026
Bay Club Hotel & Marina
My 3rd stay at Bay Club. Room, property and location is a real treat. Joshua at the front desk was very helpful.
Reviewed on 2 Mar 2026
Hard Rock Hotel San Diego
Extremely loud outside environment. The train changes engines and couples/uncouples loudly all night. The bar is super loud and the club has a line to get in on Saturday nights that is loud until at least 2am. Then no hot water on last day of my stay.
Reviewed on 3 Mar 2026
The DEXTRO Little Italy, BW Premier Collection
The staff were friendly.
Reviewed on 3 Mar 2026
Days Inn by Wyndham San Diego Hotel Circle
Even though our room was clean, our bed still had black ants crawling atop of it. Disappointing.
Reviewed on 3 Mar 2026
Best Western Seven Seas
The towels, pillow cases and beddings are too old and dirty
Reviewed on 2 Mar 2026
Other neighbourhoods around Serra Mesa
Mission Valley
Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Mission Valley Mall and Fashion Valley Mall, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Old Town San Diego
The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
Serra Mesa
Explore a world of travel with Expedia
- Hotels with free parking in Downtown San Diego
- Hotels near Fashion Valley Mall
- Gaslamp Quarter Hotels
- Hotels with Gyms in Hillcrest
- Ksl Resorts in Hillcrest
- Hotels with Spa in Hillcrest
- Hillcrest Hotels
- Hotels near Hotel Circle
- Kearny Mesa Hotels
- Linda Vista Hotels
- Little Italy Hotels
- Mid-City Hotels
- Hotels with Gyms in Mission Valley
- Condo Rentals in San Diego
- Condominium Resorts in San Diego County
- Marriott Hotels & Resorts in San Diego
- San Diego Hotels
- Flights from Montgomery Field
- Alaska Airlines Charleston (CHS) to San Diego (SAN) flights
- Alaska Airlines Anchorage (ANC) to San Diego (SAN) flights
- American Airlines Manchester (MAN) to San Diego (SAN) flights
- Finnair London (LON) to San Diego (SAN) flights
- Flights from Acapulco (ACA) to San Diego (SAN)
- Flights from San Rafael (AFA) to San Diego (SAN)
- Flights from Alice (ALI) to San Diego (MYF)
- Flights from Alpena (APN) to San Diego (SAN)
- Flights from Artesia (ATS) to San Diego (SAN)
- Flights from Auburn (AUO) to San Diego (SAN)
- Flights from Hartford (BDL) to San Diego (MYF)
- Flights from Belize City (BZE) to San Diego (SAN)
- Flights from Chicago (CHI) to San Diego (SAN)
- Flights from Charlottesville (CHO) to San Diego (MYF)
- Flights from Mosinee (CWA) to San Diego (SAN)
- Flights from Dallas (DAL) to San Diego (SAN)
- Flights from Debrecen (DEB) to San Diego (SAN)
- Flights from Detroit (DTW) to San Diego (SAN)
- Flights from Helsinki (HEL) to San Diego (SAN)
- Flights from Hawthorne (HHR) to San Diego (SAN)
- Flights from Honolulu (HNL) to San Diego (SAN)
- Flights from Washington (IAD) to San Diego (SAN)
- Flights from Iloilo (ILO) to San Diego (SAN)
- Flights from Iwakuni (IWK) to San Diego (SAN)
- Flights from Kano (KAN) to San Diego (SAN)
- Flights from Osaka (KIX) to San Diego (SAN)
- Flights from Miyazaki (KMI) to San Diego (SAN)
- Flights from Kuala Lumpur (KUL) to San Diego (SAN)
- Flights from Los Angeles (LAX) to San Diego (SAN)
- Flights from Leipzig (LEJ) to San Diego (SAN)
- Flights from New York (LGA) to San Diego (SAN)
- Flights from Laval (LVA) to San Diego (SAN)
- Flights from Manila (MNL) to San Diego (SAN)
- Flights from Modesto (MOD) to San Diego (SAN)
- Flights from Monterey (MRY) to San Diego (SAN)
- Flights from New Orleans (MSY) to San Diego (SAN)
- Flights from Myrtle Beach (MYR) to San Diego (SAN)
- Flights from Ontario (ONT) to San Diego (SAN)
- Flights from Portland (PDX) to San Diego (SAN)
- Flights from Phoenix (PHX) to San Diego (SAN)
- Flights from Pittsburgh (PIT) to San Diego (SAN)
- Flights from Pangkalanbuun (PKN) to San Diego (SAN)
- Flights from Rapid City (RAP) to San Diego (MYF)
- Flights from Russian Mission (RSH) to San Diego (SAN)
- Flights from Sacramento (SAC) to San Diego (SAN)
- Flights from San Antonio (SAT) to San Diego (SAN)
- Flights from Santo Domingo (SDQ) to San Diego (SAN)
- Flights from Seattle (SEA) to San Diego (SAN)
- Flights from Sonderborg (SGD) to San Diego (SAN)
- Flights from Salt Lake City (SLC) to San Diego (SAN)
- Flights from Sacramento (SMF) to San Diego (MYF)
- Flights from Tirana (TIA) to San Diego (SAN)
- Flights from Tampa (TPA) to San Diego (SAN)
- Flights from Tokyo (TYO) to San Diego (SAN)
- Flights from Santa Cruz (VVI) to San Diego (SAN)
- Flights from Powell River (YPW) to San Diego (SAN)
- Flights from Montreal (YUL) to San Diego (SAN)
- Visit Otay
- Visit Chula Vista
- Visit Coronado Island
- Visit Coronado
- Visit El Cajon
- Visit Jamacha
- Visit Jamul
- Visit La Jolla
- Visit La Mesa
- Visit Oceanside
- Old Town San Diego State Park
- Visit Ramona
- Visit San Diego County
- Visit Marina District
- Visit Mira Mesa
- Visit Mission Valley
- San Diego Natural History Museum
- San Diego Zoo
- Visit San Diego
- Visit Santa Ysabel
- Visit Santee
- Visit Solana Beach
- Visit Vista
