Medical Center District

San Antonio

River walk in San Antonio
River walk in San Antonio
SanAntonio_SouthTexasMedicalCenter_6193120_01

Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is RM351 per night from 9 Mar to 10 Mar
RM351
RM414 total
9 Mar - 10 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,224 reviews)
We've stayed at several hotels in the past week as we were traveling, our bed here was the best out of all of them

Reviewed on 8 Mar 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is RM399 per night from 27 Mar to 28 Mar
RM399
RM475 total
27 Mar - 28 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,008 reviews)
Desayuno desastroso

Reviewed on 8 Mar 2026

San Antonio Marriott Northwest Medical Center
Park Inn by Radisson

Park Inn by Radisson

2 out of 5
7500 Louis Pasteur Drive San Antonio TX
The price is RM252 per night from 22 Mar to 23 Mar
RM252
RM294 total
22 Mar - 23 Mar
includes taxes & fees
Stay at this motel in San Antonio. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular attractions ...
7.2/10 Good! (1,006 reviews)
Nothing out of the ordinary but in a good way.

Reviewed on 28 Feb 2026

Park Inn by Radisson
Sonesta ES Suites San Antonio Downtown Alamo Plaza

Sonesta ES Suites San Antonio Downtown Alamo Plaza

3 out of 5
425 Bonham San Antonio TX
The price is RM325 per night from 10 Mar to 11 Mar
RM325
RM385 total
10 Mar - 11 Mar
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (2,018 reviews)
Nice staff and clean rooms.

Reviewed on 7 Mar 2026

Sonesta ES Suites San Antonio Downtown Alamo Plaza
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (6,416 reviews)
Elevator was so dirty like walls have never been clean floor dirty and stain. Walking to our room carpet was dirty. Room needed to be cleaned better there was hair in the bathroom dust under tv stand. Room smelled misty Not happy with condition. I will not recommend

Reviewed on 8 Mar 2026

Riverwalk Plaza
Crockett Hotel

Crockett Hotel

3 out of 5
320 Bonham San Antonio TX
The price is RM466 per night from 16 Mar to 17 Mar
RM466
RM551 total
16 Mar - 17 Mar
includes taxes & fees
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, valet parking (surcharge) and a 24-hour front desk. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,605 reviews)
The staff went above and beyond to bake our stay wonderful!

Reviewed on 7 Mar 2026

Crockett Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Dub Farris Athletic Complex are top sights worth seeing.

Northwest Side
Sam's Burger Joint

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.

Midtown
Historic architecture Spanish San Antonio Texas Mission San Jose on a cloudy day

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
One of the coolest bars in San Antonio. Definitely check it out.

Tobin Hill

Tobin Hill might not have many top sights, but San Antonio Zoo and Aquarium and San Antonio Museum of Art are two attractions nearby that you can check out.

Tobin Hill
Marion Koogler McNay Art Museum which includes art and interior views as well as an individual male

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Uptown
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Alamo Heights

You'll enjoy the museums and coffee shops in Alamo Heights. You might want to make time for a stop at San Antonio River or Toilet Seat Museum.

Alamo Heights


Medical Center District