South Carolina Midlands hotels from RM259

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South Carolina Midlands hotels

Studio 6 West Columbia, SC - Airport

Studio 6 West Columbia, SC - Airport
2.0 star property
West Columbia
6.4 out of 10, (11 reviews)
"The room bathroom had a leaky toilet, broken tub, rooms were dirty, sheets were dirty. No blackout curtain at night , light would shine inside the room. "
United States
Victor
The price is RM294
RM317 total
includes taxes & fees
11 Feb - 12 Feb
Studio 6 West Columbia, SC - Airport

Inn on the Square, an Ascend Collection Hotel

Inn on the Square, an Ascend Collection Hotel
3.0 star property
Uptown Greenwood
9.2 out of 10, Wonderful, (713 reviews)
"It was a very clean and beautiful lace to stay. We were there for our honeymoon "
United States
Tracy
The price is RM416
RM462 total
includes taxes & fees
1 Mar - 2 Mar
Inn on the Square, an Ascend Collection Hotel

Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC
2.5 star property
Cayce
8.4 out of 10, Very good, (1,002 reviews)
"Breakfast was great "
United States
Mayah
The price is RM367
RM407 total
includes taxes & fees
8 Mar - 9 Mar
Country Inn & Suites by Radisson, Columbia Airport, SC

Holiday Inn Express Richburg by IHG

Holiday Inn Express Richburg by IHG
2.5 star property
Richburg
9.2 out of 10, Wonderful, (653 reviews)
"Needed a last-minute place to stay due to bad roads and was very happy with my experience at Holiday Inn. The room was clean, the breakfast was great, and the staff were incredibly friendly and helpful. Really appreciated the welcoming atmosphere during a stressful travel situation."
United States
Sarah
The price is RM425
RM476 total
includes taxes & fees
8 Feb - 9 Feb
Holiday Inn Express Richburg by IHG

Hyatt Place Columbia/Harbison

Hyatt Place Columbia/Harbison
3.0 star property
Irmo
8.0 out of 10, Very good, (1,002 reviews)
" Great hotel "
United States
Brian
The price is RM279
RM313 total
includes taxes & fees
17 Feb - 18 Feb
Hyatt Place Columbia/Harbison

Residence Inn by Marriott Columbia Northwest/Harbison

Residence Inn by Marriott Columbia Northwest/Harbison
3.0 star property
Irmo
9.2 out of 10, Wonderful, (607 reviews)
"Very nice staff and rooms "
United States
Timothy
The price is RM448
RM484 total
includes taxes & fees
8 Feb - 9 Feb
Residence Inn by Marriott Columbia Northwest/Harbison

Hampton Inn & Suites Lexington Columbia

Hampton Inn & Suites Lexington Columbia
2.5 star property
Lexington
9.8 out of 10, Exceptional, (614 reviews)
"Clean and great staff"
United States
Sean
The price is RM467
RM518 total
includes taxes & fees
8 Feb - 9 Feb
Hampton Inn & Suites Lexington Columbia

Staybridge Suites Charlotte Ballantyne by IHG

Staybridge Suites Charlotte Ballantyne by IHG
3.0 star property
Ballantyne
8.6 out of 10, Excellent, (1,010 reviews)
"Great hotel and great staff. The location was safe with lots to do."
United States
julie
The price is RM405
RM467 total
includes taxes & fees
8 Feb - 9 Feb
Staybridge Suites Charlotte Ballantyne by IHG

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
2.5 star property
Santee
9.8 out of 10, Exceptional, (1,007 reviews)
"Our room was super clean, breakfast was good. And the hotel was nice and quiet."
United States
john
The price is RM547
RM607 total
includes taxes & fees
1 Mar - 2 Mar
Fairfield Inn & Suites by Marriott Santee

Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista
3.5 star property
Downtown Columbia
9.4 out of 10, Exceptional, (1,185 reviews)
"Great place "
United States
Jeff
The price is RM469
RM525 total
includes taxes & fees
8 Feb - 9 Feb
Cambria Hotel Columbia Downtown The Vista

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison
3.0 star property
Columbia
9.0 out of 10, Wonderful, (1,961 reviews)
"Great stay! "
United States
Dana
The price is RM351
RM394 total
includes taxes & fees
15 Feb - 16 Feb
Hilton Garden Inn Columbia/Harbison

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,000 reviews)
"Liked the size of the room, the staff and the breakfast."
United States
Virginia
The price is RM535
RM594 total
includes taxes & fees
1 Mar - 2 Mar
Hampton Inn Santee-I-95

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,004 reviews)
"Clean rooms, nice staff, decent breakfast "
United States
Dale
The price is RM403
RM448 total
includes taxes & fees
8 Feb - 9 Feb
Comfort Inn & Suites Santee

Holiday Inn Express Hotel & Suites Camden-I20 (Hwy 521) by IHG

Holiday Inn Express Hotel & Suites Camden-I20 (Hwy 521) by IHG
2.5 star property
Camden
8.4 out of 10, Very good, (705 reviews)
"Room was perfect and the breakfast was great."
United States
Aveory
The price is RM440
RM493 total
includes taxes & fees
15 Feb - 16 Feb
Holiday Inn Express Hotel & Suites Camden-I20 (Hwy 521) by IHG

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,000 reviews)
"Nice rooms and very good breakfast items."
United States
Stephen
The price is RM468
RM519 total
includes taxes & fees
12 Feb - 13 Feb
Best Western Plus Santee Inn

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
3.0 star property
Columbia
7.8 out of 10, Good, (1,017 reviews)
"Room was nice and excellent staff"
United States
Arvette
The price is RM297
RM340 total
includes taxes & fees
1 Mar - 2 Mar
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

Hampton Inn & Suites Columbia Killian Road

Hampton Inn & Suites Columbia Killian Road
2.5 star property
Columbia
9.2 out of 10, Wonderful, (1,020 reviews)
"Great hotel with a convenient location. "
United States
vielka
The price is RM448
RM502 total
includes taxes & fees
15 Feb - 16 Feb
Hampton Inn & Suites Columbia Killian Road

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (956 reviews)
"Room clean, bed good, breakfast good choices, front desk excellent"
United States
mona
The price is RM531
RM595 total
includes taxes & fees
1 Mar - 2 Mar
Staybridge Suites Florence - Civic Center by IHG

Comfort Suites Columbia at Harbison

Comfort Suites Columbia at Harbison
2.5 star property
Columbia
8.0 out of 10, Very good, (1,007 reviews)
"Great stay!"
United States
Shaunice
The price is RM331
RM367 total
includes taxes & fees
8 Feb - 9 Feb
Comfort Suites Columbia at Harbison

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
3.0 star property
Columbia
8.8 out of 10, Excellent, (1,853 reviews)
"Great staff, and amazing room"
United States
Joel
The price is RM343
RM385 total
includes taxes & fees
15 Feb - 16 Feb
La Quinta Inn by Wyndham Columbia NE/Fort Jackson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Holiday Rentals in South Carolina Midlands

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeastern United States attractions

Learn more about South Carolina Midlands

With Revolutionary War sites, a charming capital city and lots of kayaking opportunities, this southern region is sure to delight.

South Carolina State House featuring a sunset, heritage architecture and a park

Top South Carolina Midlands Hotel Reviews

More cheap stays in South Carolina Midlands

Explore a world of travel with Expedia