Southeast Missouri Kid friendly Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to RM 324 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,008 reviews)
Nice place to stop.
"Nice, clean hotel. It’s a very small town, but there is fast food nearby and close to the interstate. We made a quick one night stop but enjoyed the indoor/outdoor pool and indoor hot tub. The parking lot was very wel lit and the area felt safe."
Reviewed on 30 Jun 2025
Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
Nice place to stay
"They didn’t have our room ready when we got there close to 4pm. We waited approx 20min when three more people showed up. These 3 people received rooms right away while we sat and waited."
Reviewed on 30 Jun 2025
Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,003 reviews)
"Friendly"
Reviewed on 23 Jun 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.