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Hotels near UCSF Mission Bay

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Our top choices for UCSF Mission Bay hotels

HI San Francisco Downtown Hostel

HI San Francisco Downtown Hostel
2.0 star property
Union Square, 2.5 km from UCSF Mission Bay
9.0 out of 10, Wonderful, (372)
"Clean room, friendly staff"
United States
mark ryan
The price is RM288
RM335 total
includes taxes & fees
4 Jan - 5 Jan 2026
HI San Francisco Downtown Hostel

Hyatt Regency San Francisco

Hyatt Regency San Francisco
4.0 star property
Financial District, 2.8 km from UCSF Mission Bay
9.2 out of 10, Wonderful, (2016)
"Excellent location, Clean rooms and beautiful interior "
United States
Balasasindran
The price is RM653
RM954 total
includes taxes & fees
23 Jan - 24 Jan 2026
Hyatt Regency San Francisco

The Marker Union Square San Francisco

The Marker Union Square San Francisco
4.0 star property
2.6 km from UCSF Mission Bay
9.0 out of 10, Wonderful, (1128)
"The staff was so fabulous, the hotel is gorgeous, and we are already having the best time!"
United States
Faith
The price is RM566
RM666 total
includes taxes & fees
3 Jan - 4 Jan 2026
The Marker Union Square San Francisco

Stanford Court San Francisco

Stanford Court San Francisco
4.0 star property
Nob Hill, 3 km from UCSF Mission Bay
9.0 out of 10, Wonderful, (1326)
"Very good location!"
United States
robin
The price is RM493
RM761 total
includes taxes & fees
4 Jan - 5 Jan 2026
Stanford Court San Francisco

Bay Bridge Inn

Bay Bridge Inn
2.0 star property
South of Market, 1.4 km from UCSF Mission Bay
7.6 out of 10, Good, (1004)
"Easy and affordable "
United States
Justin
Bay Bridge Inn

FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill
2.0 star property
3.1 km from UCSF Mission Bay
8.6 out of 10, Excellent, (1142)
"such clean rooms & wonderful staff they are very helpful felt so comfortable in my stay!"
United States
heidi
The price is RM291
RM342 total
includes taxes & fees
25 Jan - 26 Jan 2026
FOUND Hotel Carlton, Nob Hill

Hotel Garrett

Hotel Garrett
3.0 star property
South of Market, 2 km from UCSF Mission Bay
7.8 out of 10, Good, (718)
"Great staff and clean room. "
United States
Colleen Sue
Hotel Garrett

Palihotel San Francisco

Palihotel San Francisco
3.5 star property
Union Square, 2.7 km from UCSF Mission Bay
8.4 out of 10, Very good, (632)
"Great vibe here and the rooms and so cute . Excellent bar and bar staff . "
United States
Lana
The price is RM405
RM578 total
includes taxes & fees
30 Dec - 31 Dec
Palihotel San Francisco

The Urban

The Urban
2.5 star property
Union Square, 2.7 km from UCSF Mission Bay
8.0 out of 10, Very good, (917)
"Clean, quiet and staff very polite. Had a really good stay."
United States
Pranita
The price is RM245
RM288 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Urban

Adelaide Hostel

Adelaide Hostel
2.0 star property
2.7 km from UCSF Mission Bay
8.0 out of 10, Very good, (633)
"I needed a quick place to stay after making a mistake with my flight. The price for the 4 bed to a room was very good. The hostel is clean and the staff was very helpful. You can't expect "quiet" when you're in the Union Square area, but I was happy with my stay."
United States
Michael
The price is RM379
RM445 total
includes taxes & fees
30 Dec - 31 Dec
Adelaide Hostel

Fitzgerald Hotel

Fitzgerald Hotel
3.0 star property
2.7 km from UCSF Mission Bay
7.8 out of 10, Good, (510)
"Clean, friendly staff and cheap price where the hotel location is in the centre of the city"
Australia
Trong Anh
Fitzgerald Hotel

Hayes Valley Inn

Hayes Valley Inn
2.0 star property
2.9 km from UCSF Mission Bay
7.8 out of 10, Good, (318)
"Basic accommodation but clean and in a good area"
United Kingdom
Daniel
The price is RM308
RM358 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hayes Valley Inn

Amsterdam Hostel

Amsterdam Hostel
2.0 star property
2.9 km from UCSF Mission Bay
7.8 out of 10, Good, (202)
"Clean, walkable and quiet hostel with plenty of food within walking distance."
United States
Daniel
The price is RM231
RM271 total
includes taxes & fees
2 Jan - 3 Jan 2026
Amsterdam Hostel

City Center Inn & Suites

City Center Inn & Suites
2.0 star property
South of Market, 1.7 km from UCSF Mission Bay
7.2 out of 10, Good, (927)
"Good Hotel"
United States
Karla
City Center Inn & Suites

Orange Village Hostel

Orange Village Hostel
1.5 star property
2.6 km from UCSF Mission Bay
7.4 out of 10, Good, (989)
"Some of the best staff Ive encountered in hostels. Very friendly overall atmosphere and vibe. "
United States
Eugene
Orange Village Hostel

San Francisco Inn

San Francisco Inn
2.0 star property
South of Market, 1.6 km from UCSF Mission Bay
7.0 out of 10, Good, (1001)
"The price point is good, on site parking is a bonus. "
United States
JONATHAN
San Francisco Inn

Edwardian Hotel

Edwardian Hotel
2.0 star property
2.7 km from UCSF Mission Bay
7.4 out of 10, Good, (374)
"The Edwardian was perfect for my needs. The room and bathroom were clean and the location was excellent."
United States
Paul
The price is RM320
RM373 total
includes taxes & fees
9 Jan - 10 Jan 2026
Edwardian Hotel

Kasa La Monarca San Francisco

Kasa La Monarca San Francisco
3.5 star property
2.8 km from UCSF Mission Bay
7.8 out of 10, Good, (184)
"Completely contactless service which allows a calmer experience."
United States
Sicily
Kasa La Monarca San Francisco

The Herbert Hotel

The Herbert Hotel
2.5 star property
Union Square, 2.4 km from UCSF Mission Bay
7.4 out of 10, Good, (1003)
"Great stay…"
United States
Scot
The price is RM283
RM335 total
includes taxes & fees
28 Jan - 29 Jan 2026
The Herbert Hotel

Union Hotel

Union Hotel
2.0 star property
2.5 km from UCSF Mission Bay
7.0 out of 10, Good, (291)
"Great for the price point. Friendly staff and quiet hotel."
United States
Michael
The price is RM219
RM255 total
includes taxes & fees
4 Jan - 5 Jan 2026
Union Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top UCSF Mission Bay Hotel Reviews

Hotels near other UCSF Mission Bay attractions

Frequently asked questions

What's the area like around UCSF Mission Bay?
UCSF Mission Bay is located in a vibrant area of San Francisco known for its top museums and stunning architecture. If you're looking for a convenient place to stay, take a look at the 85 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near UCSF Mission Bay?
Hyatt Place San Francisco Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers a bar and free WiFi. It's located just a short 0.7 mi (1.1 km) from UCSF Mission Bay. Other good choices within a short distance include LUMA Hotel San Francisco and Hotel VIA.
How many hotels will I be able to find close to UCSF Mission Bay?
Expedia has 85 hotels and other accommodation options within a mile from UCSF Mission Bay.
If I need to cancel the hotel reservation for my stay near UCSF Mission Bay, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then use the filter option "fully refundable" to view top deals close to UCSF Mission Bay.
What can I see and do near UCSF Mission Bay?
Study the collections at San Francisco Museum of Modern Art, Asian Art Museum of San Francisco or Market Street Railway Museum. Sights like San Francisco Mint, 450 Sutter Building and Ferry Building are landmarks to visit in the area. You can check out the local talent at Golden Gate Theatre, Warfield Theatre and Orpheum Theatre.
How can I get to UCSF Mission Bay?
With so many choices for transport, seeing all of the area near UCSF Mission Bay is simple. You can access metro transport at Market St & 5th St Stop, Market St & Taylor St Stop and Powell St & Market St Stop. If you're hopping a train into the city, San Francisco Station is the closest station to Downtown San Francisco.