A coastal landscape with rocky cliffs, clear blue waters, and distant mountains.

Best Boutique Hotels in San Luis Obispo Wine Country

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on San Luis Obispo Wine Country Boutique Hotels

Tonight
23 Oct - 24 Oct
Tomorrow
24 Oct - 25 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov
No exact matches found, but these alternatives could be just right

Recommended hotels in San Luis Obispo Wine Country

A modern outdoor lounge area with a fireplace, seating, and a glass railing overlooking a cityscape.
A modern lobby with a fireplace, two armchairs, a round coffee table, a sofa, and a floor lamp.
A modern bar area with a central counter, bar stools, and shelves stocked with bottles and glasses.
A modern living room with a sectional sofa, glass coffee tables, and a large abstract painting.

1. La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
San Luis Obispo
United States
Jehmae
RM521
RM592 total
includes taxes & fees
1 Nov - 2 Nov
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
A spacious outdoor seating area with wicker furniture and turquoise cushions, overlooking a white building with teal accents.
A buffet area with various food items and a coffee station.
A pool area with wicker furniture and umbrellas, surrounded by a white building with balconies.
A spacious lobby with a fireplace, comfortable seating, and large potted plants.

2. Quality Suites Downtown San Luis Obispo

Quality Suites Downtown San Luis Obispo
San Luis Obispo
United States
Daniel
RM464
RM629 total
includes taxes & fees
1 Nov - 2 Nov
Quality Suites Downtown San Luis Obispo
A swimming pool with lounge chairs, a small chapel, and a waterfall.
A cave-like interior with a red-framed window, stone walls, and a small table with a red object.
A bar area with wooden beams, a colorful carpet, and a variety of bar stools.
A pool area with lounge chairs and umbrellas, a gazebo, and a waterfall.

3. Madonna Inn

Madonna Inn
San Luis Obispo
United States
Bertha
RM608
RM829 total
includes taxes & fees
4 Nov - 5 Nov
Madonna Inn
A patio with a fire pit and chairs overlooking a coastal landscape with mountains and a body of water.
A cozy living room with a stone fireplace, comfortable seating, and artwork on the walls.
A coastal hotel with a paved walkway along the beach, a view of the ocean, and a hillside with vegetation.
A landscaped garden with palm trees, a pathway, and a view of the ocean.

4. Spyglass Inn

Spyglass Inn
Pismo Beach
United States
Margarito
RM524
RM601 total
includes taxes & fees
15 Nov - 16 Nov
Spyglass Inn
A spacious lobby with a high ceiling, a central seating area with sofas and armchairs, and a large hanging light fixture.
A spacious indoor dining area with a long table, multiple chairs, hanging pendant lights, and potted plants.
A modern bar area with a long counter, multiple bar stools, and a high ceiling with exposed beams.
A modern hotel with a sign reading "Embassy Suites" and a covered entrance.

5. Embassy Suites by Hilton San Luis Obispo

Embassy Suites by Hilton San Luis Obispo
San Luis Obispo
United States
Robin
RM465
RM529 total
includes taxes & fees
22 Nov - 23 Nov
Embassy Suites by Hilton San Luis Obispo
A hotel with multiple buildings, green roofs, and outdoor seating areas.
A spacious living room with a blue sofa, patterned armchair, and a coffee table with a vase of red flowers.
A large house with a swimming pool, a covered patio, and a view of a mountain.
A hotel with a large pool, outdoor seating, and a mountain backdrop.

6. Apple Farm

Apple Farm
San Luis Obispo
United States
Alfredo
RM437
RM544 total
includes taxes & fees
1 Nov - 2 Nov
Apple Farm
A brick-paved entrance with a green door, white columns, and a covered porch.
A dining area with a large table set for six, surrounded by white chairs, a chandelier, and large windows with stained glass.
A garden street inn with a red awning, a bench, and a well-maintained garden.
A cozy living room with a fireplace, a bookshelf filled with books, a comfortable armchair, and a dining area with a table and chairs.

7. Garden Street Inn, A Kirkwood Collection Hotel

Garden Street Inn, A Kirkwood Collection Hotel
Downtown San Luis Obispo
United States
Martin
RM434
RM492 total
includes taxes & fees
17 Nov - 18 Nov
Garden Street Inn, A Kirkwood Collection Hotel
A kitchen with white paneled walls, a wooden countertop, a ceiling light fixture, a large white vase with dried plants, a woven basket, and a patterned rug on the floor.
A bedroom with a large bed, two smaller beds, a fireplace, and a view of the outdoors.
A sign for San Luis Creek Lodge with outdoor seating.
A room with a fireplace, a framed abstract artwork, a wicker chair, a small round table with a book, and a window with curtains.

8. San Luis Creek Lodge

San Luis Creek Lodge
San Luis Obispo
United States
Rosanna
RM549
RM699 total
includes taxes & fees
26 Oct - 27 Oct
San Luis Creek Lodge
A modern living room with green sofas, a fireplace, and a large bookshelf filled with books.
A hotel with a white facade, a sign reading "The Ritz-Carlton," and a view of green hills in the background.
A spacious lobby with a wooden reception desk, a large seating area, a hanging chair, and a bookshelf filled with books.
An outdoor patio with hexagonal tiles, wooden benches, and tables with chairs. There are string lights overhead and a fire feature in the center.

9. The Wayfarer San Luis Obispo, Tapestry Collection by Hilton

The Wayfarer San Luis Obispo, Tapestry Collection by Hilton
San Luis Obispo
United States
Caroline
RM419
RM476 total
includes taxes & fees
28 Oct - 29 Oct
The Wayfarer San Luis Obispo, Tapestry Collection by Hilton
A modern hotel entrance with a covered walkway, stone pillars, and a bench.
A hotel room with a bed, a TV, a desk, and a chair.
A hotel bathroom with a granite countertop, a sink, a mirror, a coffee maker, and a trash can.
A modern hotel lobby with wooden flooring, a green sofa, a wooden reception desk, and a television screen.

10. Hampton Inn & Suites San Luis Obispo

Hampton Inn & Suites San Luis Obispo
San Luis Obispo
United States
Claudia
RM432
RM491 total
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn & Suites San Luis Obispo
View all properties

Top San Luis Obispo Wine Country Hotel Reviews

Apple Farm

Apple Farm

10/10 Excellent
"Great place!! Friendly service. Great location."
Timothy 2-night trip
Posted 18 hours ago
Apple Farm
La Cuesta Inn, BW Signature Collection

La Cuesta Inn, BW Signature Collection

10/10 Excellent
"Had a great experience from day one to the last day of my stayed. I would return and visit this place again."
Carlos 3-night trip
Posted 1 day ago
La Cuesta Inn, BW Signature Collection

Explore a world of travel with Expedia