Top 10 Hotels Near Mayo Clinic in Rochester for 2026

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Our top choices for Mayo Clinic hotels

An outdoor patio area with a concrete floor, wooden fence, and string lights.

1. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park, 1.8 km from Mayo Clinic

Brien

RM523 total

includes taxes & fees

22 Nov - 23 Nov

A coffee shop interior with a wooden counter, menu boards, and seating area.

2. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 0.4 km from Mayo Clinic

Neil

RM642 total

includes taxes & fees

11 Dec - 12 Dec

A modern living room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a view of a cityscape through large windows.

3. Hilton Rochester Mayo Clinic Area

Downtown Rochester, 0.3 km from Mayo Clinic

Jennifer

RM793 total

includes taxes & fees

27 Nov - 28 Nov

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

4. Residence Inn by Marriott Rochester Mayo Clinic Area South

2.4 km from Mayo Clinic

Chee

RM619 total

includes taxes & fees

27 Nov - 28 Nov

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

5. The Berkman

Folwell, 1.4 km from Mayo Clinic

Suzette

RM851 total

includes taxes & fees

1 Dec - 2 Dec

A modern indoor patio with a fire feature, seating, and large windows.

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 1 km from Mayo Clinic

Ashley

RM590 total

includes taxes & fees

26 Nov - 27 Nov

A modern living room with a fireplace, comfortable seating, and large windows.

7. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 1 km from Mayo Clinic

Sheri

RM498 total

includes taxes & fees

25 Nov - 26 Nov

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

8. Home2 Suites by Hilton Rochester Mayo Clinic Area

2.6 km from Mayo Clinic

howard

RM512 total

includes taxes & fees

13 Dec - 14 Dec

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

9. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 1.4 km from Mayo Clinic

Paul

RM512 total

includes taxes & fees

25 Nov - 26 Nov

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

10. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 0.5 km from Mayo Clinic

Robert Blaise

RM521 total

includes taxes & fees

27 Nov - 28 Nov

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

11. Econo Lodge Mayo Clinic Area

3.1 km from Mayo Clinic

Britta

RM315 total

includes taxes & fees

12 Dec - 13 Dec

A hotel with a stone facade, multiple windows, and a sign indicating it is Candlewood Suites.

12. Candlewood Suites Rochester Mayo Clinic Area by IHG

2.6 km from Mayo Clinic

Kevin

RM502 total

includes taxes & fees

15 Nov - 16 Nov

A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

13. Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester, 0.3 km from Mayo Clinic

Jennifer

RM790 total

includes taxes & fees

27 Nov - 28 Nov

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

14. Hampton Inn Rochester-South

2.9 km from Mayo Clinic

Susan

RM454 total

includes taxes & fees

12 Dec - 13 Dec

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

15. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Kutzky Park, 1.4 km from Mayo Clinic

francis

RM530 total

includes taxes & fees

27 Nov - 28 Nov

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

16. Aspen Suites

1.2 km from Mayo Clinic

Lee

RM651 total

includes taxes & fees

26 Nov - 27 Nov

A spacious outdoor dining area with multiple tables and chairs, large windows, and a wooden ceiling structure.

17. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester, 0.4 km from Mayo Clinic

Kathleen

RM455 total

includes taxes & fees

28 Nov - 29 Nov

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

18. Brentwood Inn & Suites

Downtown Rochester, 0.3 km from Mayo Clinic

Anne

RM560 total

includes taxes & fees

14 Nov - 15 Nov

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

19. Quality Inn & Suites Mayo Clinic Area

2.6 km from Mayo Clinic

Mark

RM329 total

includes taxes & fees

4 Dec - 5 Dec

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

20. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 0.3 km from Mayo Clinic

Richard

RM554 total

includes taxes & fees

11 Dec - 12 Dec

View all properties

Compare popular hotels close to Mayo Clinic

Property	Property class	Guest rating
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	3.0 star property	9.6 Exceptional 754 reviews	View
TownePlace Suites by Marriott Rochester Mayo Clinic Area	3.0 star property	9.6 Exceptional 577 reviews	View
Hilton Rochester Mayo Clinic Area	3.5 star property	9.6 Exceptional 657 reviews	View
Residence Inn by Marriott Rochester Mayo Clinic Area South	3.0 star property	9.6 Exceptional 321 reviews	View
The Berkman	3.0 star property	9.6 Exceptional 455 reviews	View

Hotels recommended for families near Mayo Clinic

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

RM455 total

includes taxes & fees

28 Nov - 29 Nov

Frequently Asked Questions

What's the area like around Mayo Clinic?

Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 153 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to Mayo Clinic?

Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area.

How many hotels should I expect to find near Mayo Clinic?

Expedia has 153 hotels and other accommodation options within a mile from Mayo Clinic.

If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?

Yes, most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the best deals near Mayo Clinic.

What can I see and do near Mayo Clinic?

You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Assisi Heights and Plummer House. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

Hotels near Mayo Clinic

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Our top choices for Mayo Clinic hotels

1. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

2. TownePlace Suites by Marriott Rochester Mayo Clinic Area

3. Hilton Rochester Mayo Clinic Area

4. Residence Inn by Marriott Rochester Mayo Clinic Area South

5. The Berkman

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

7. Staybridge Suites Rochester - Mayo Clinic Area by IHG

8. Home2 Suites by Hilton Rochester Mayo Clinic Area

9. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

10. Hyatt House Rochester/Mayo Clinic Area

11. Econo Lodge Mayo Clinic Area

12. Candlewood Suites Rochester Mayo Clinic Area by IHG

13. Broadway Plaza, Trademark Collection by Wyndham

14. Hampton Inn Rochester-South

15. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

16. Aspen Suites

17. Hotel Indigo Rochester – Mayo Clinic Area by IHG

18. Brentwood Inn & Suites

19. Quality Inn & Suites Mayo Clinic Area

20. Hilton Garden Inn Rochester Downtown, MN

Compare popular hotels close to Mayo Clinic

Hotels recommended for families near Mayo Clinic

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Frequently Asked Questions

What's the area like around Mayo Clinic?

What's the best place to stay close to Mayo Clinic?

How many hotels should I expect to find near Mayo Clinic?

If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?

What can I see and do near Mayo Clinic?

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