Top 10 Hotels Near Mayo Clinic Hospital - Saint Marys Campus in Rochester for 2026

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Our top choices for Mayo Clinic Hospital - Saint Marys Campus hotels

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern hotel room with a bed, desk, and kitchenette.

A modern restaurant with a counter, seating area, and a TV screen.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

1. Home2 Suites by Hilton Rochester Mayo Clinic Area

2.3 km from Mayo Clinic Hospital - Saint Marys Campus

howard

RM518

RM596 total

includes taxes & fees

24 Oct - 25 Oct

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel room with a bed, bedside table, and a window with curtains.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

2. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 1 km from Mayo Clinic Hospital - Saint Marys Campus

Robin M.

RM560

RM645 total

includes taxes & fees

24 Oct - 25 Oct

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

3. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park, 0.9 km from Mayo Clinic Hospital - Saint Marys Campus

Jon

RM456

RM525 total

includes taxes & fees

17 Oct - 18 Oct

A modern living room with a flat-screen TV, a fireplace, comfortable seating, and a large window with a city view.

A spacious lobby with modern furniture, a spiral staircase, and large windows offering views of the outdoors.

A modern indoor swimming pool with seating areas and a city view.

A modern hotel entrance with a glass facade, illuminated signage, and a covered walkway.

4. Hilton Rochester Mayo Clinic Area

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

Raymond

RM761

RM876 total

includes taxes & fees

17 Oct - 18 Oct

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

A modern hotel with a flat roof, multiple windows, and a covered outdoor seating area.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

5. Residence Inn by Marriott Rochester Mayo Clinic Area South

2.3 km from Mayo Clinic Hospital - Saint Marys Campus

Chee

RM540

RM621 total

includes taxes & fees

17 Oct - 18 Oct

A modern indoor patio with a fire feature, seating, and large windows.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 0.4 km from Mayo Clinic Hospital - Saint Marys Campus

Rici

RM483

RM611 total

includes taxes & fees

6 Nov - 7 Nov

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with a brick facade.

A modern interior with a large dining table, sofas, and a kitchen area.

7. The Berkman

Folwell, 0.1 km from Mayo Clinic Hospital - Saint Marys Campus

Suzette

RM777

RM903 total

includes taxes & fees

4 Nov - 5 Nov

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 0.4 km from Mayo Clinic Hospital - Saint Marys Campus

Sheri

RM466

RM545 total

includes taxes & fees

18 Oct - 19 Oct

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

A hotel room with a bed, a sofa, a desk, a TV, and a wall art piece.

A hotel room with a sofa, armchairs, a small kitchenette, a flat-screen TV, and a large window.

9. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Kutzky Park, 0.2 km from Mayo Clinic Hospital - Saint Marys Campus

MATTHEW

RM501

RM577 total

includes taxes & fees

16 Oct - 17 Oct

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

A modern bar area with seating and a counter.

A modern indoor pool area with lounge chairs and a pool.

10. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 1.6 km from Mayo Clinic Hospital - Saint Marys Campus

Lucy

RM482

RM555 total

includes taxes & fees

17 Oct - 18 Oct

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

A conference room with multiple tables and chairs, ceiling fans, and artwork on the walls.

A modern hotel lobby with a stone wall fireplace, comfortable seating, and a chandelier.

An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

11. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 0.2 km from Mayo Clinic Hospital - Saint Marys Campus

Lin

RM547

RM630 total

includes taxes & fees

5 Nov - 6 Nov

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

A hotel room with a large round table, two sofas, a TV, and a bed.

A hotel lobby with a reception desk, seating area, and a large window.

A hotel gym with treadmills, elliptical machines, and free weights.

12. Candlewood Suites Rochester Mayo Clinic Area by IHG

2.9 km from Mayo Clinic Hospital - Saint Marys Campus

Kevin

RM474

RM546 total

includes taxes & fees

11 Oct - 12 Oct

A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

An indoor swimming pool with a clock on the wall, lounge chairs, and a lifeguard warning sign.

A modern kitchen with wooden cabinets, a granite countertop, and a stainless steel stove.

13. Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

Danny

RM691

RM796 total

includes taxes & fees

17 Oct - 18 Oct

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

14. Hampton Inn Rochester-South

3.1 km from Mayo Clinic Hospital - Saint Marys Campus

dennis

RM448

RM516 total

includes taxes & fees

18 Oct - 19 Oct

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

A hotel lobby with striped armchairs, a sofa, a fireplace, and a clock on the wall.

A hotel room with a kitchenette, a dining area with striped chairs, a sofa, a TV, and a window with curtains.

An outdoor patio area with brick walls, a large arched window, and outdoor seating.

15. Aspen Suites

0.2 km from Mayo Clinic Hospital - Saint Marys Campus

Dana

RM549

RM663 total

includes taxes & fees

23 Oct - 24 Oct

A spacious outdoor dining area with modern furniture and large windows offering views of the city.

A modern hotel room with a large bed, a sofa, a small table, a desk, and a wardrobe.

A modern interior with a wooden ceiling, a large black shelving unit, and a refrigerator stocked with beverages.

An outdoor dining area with wooden beams, tables, and chairs.

16. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester, 1.7 km from Mayo Clinic Hospital - Saint Marys Campus

thomas

RM421

RM485 total

includes taxes & fees

7 Nov - 8 Nov

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A compact kitchen with a microwave, refrigerator, and coffee maker. A small bar stool is near the counter.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

17. Quality Inn & Suites Mayo Clinic Area

2.9 km from Mayo Clinic Hospital - Saint Marys Campus

Jessica

RM312

RM363 total

includes taxes & fees

1 Nov - 2 Nov

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

A reception area with two counters, a patterned wall, and a wooden floor.

A spacious lobby with a large seating area, a fireplace, and large windows providing natural light.

A hotel room with a blue sofa, a wooden bench, a small table with a lamp, a painting of a flower, and a kitchenette in the background.

18. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 1.6 km from Mayo Clinic Hospital - Saint Marys Campus

Richard

RM483

RM556 total

includes taxes & fees

24 Oct - 25 Oct

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

A reception area with a curved counter, ceiling lights, and a potted plant.

A long, narrow hotel corridor with a carpeted floor, light fixtures along the walls, and a ceiling with recessed lighting.

19. Brentwood Inn & Suites

Downtown Rochester, 1.3 km from Mayo Clinic Hospital - Saint Marys Campus

Daniel

RM511

RM588 total

includes taxes & fees

29 Oct - 30 Oct

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A restaurant interior with wooden tables, chairs, and a stone wall.

A garden with a water feature, rocks, and yellow umbrellas.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest, 1.2 km from Mayo Clinic Hospital - Saint Marys Campus

Christine

RM467

RM538 total

includes taxes & fees

10 Oct - 11 Oct

View all properties

Compare popular hotels close to Mayo Clinic Hospital - Saint Marys Campus

Property	Property class	Guest rating
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,000 reviews	View
TownePlace Suites by Marriott Rochester Mayo Clinic Area	9.6 Exceptional 565 reviews	View
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 742 reviews	View
Hilton Rochester Mayo Clinic Area	9.6 Exceptional 649 reviews	View
Residence Inn by Marriott Rochester Mayo Clinic Area South	9.6 Exceptional 313 reviews	View

Top Mayo Clinic Hospital - Saint Marys Campus Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent

"Twigs restaurant is fantastic! Staff is very accommodating, especially as a Mayo “visitor “ it was wonderful to have one less thing to worry about! This is the only place I stay now when I go to Rochester"

Brentwood Inn & Suites

10/10 Excellent

"Wonderful location with free parking and a nice free breakfast."

Aspen Select

10/10 Excellent

"rooms were great, breakfast a little weak"

TownePlace Suites by Marriott Rochester Mayo Clinic Area

10/10 Excellent

"Easy access to Mayo with parking onsite and a free hot breakfast. Loved the kitchenette in the rooms as well."

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Great location. Great accommodations. Highly recommended."

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent

"The room was very clean. Staff were kind and pleasant upon check in."

Staybridge Suites Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"Absolutely perfect hotel, especially if you are traveling back and forth to St. Mary’s campus for Mayo. Great breakfast, free laundry, great shower, comfy bed. Best you could get in these circumstances away from home. Thank you!"

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

10/10 Excellent

"Clean room. Good breakfast."

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

8/10 Good

"Staff was good, rooms were clean but needing some updates"

Frequently asked questions

What's the area like around Mayo Clinic Hospital - Saint Marys Campus?

Mayo Clinic Hospital - Saint Marys Campus is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 123 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Mayo Clinic Hospital - Saint Marys Campus?

Adjacent to Mayo Clinic Hospital - Saint Marys Campus, The Berkman is one of the top choices for your stay based on our traveller data, and this aparthotel offers in-room kitchens and a fitness centre. Other good options within a short distance include Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area.

How many hotels are there close to Mayo Clinic Hospital - Saint Marys Campus?

Expedia has 123 hotels and other accommodation options within a mile from Mayo Clinic Hospital - Saint Marys Campus.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Hospital - Saint Marys Campus, will I receive a refund?

Yes! The majority of room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to view the best options available near Mayo Clinic Hospital - Saint Marys Campus.

What can I see and do near Mayo Clinic Hospital - Saint Marys Campus?

You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Sights like Assisi Heights and Plummer House highlight some of the local culture. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

Hotels near Mayo Clinic Hospital - Saint Marys Campus

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Be picky

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Our top choices for Mayo Clinic Hospital - Saint Marys Campus hotels

1. Home2 Suites by Hilton Rochester Mayo Clinic Area

2. TownePlace Suites by Marriott Rochester Mayo Clinic Area

3. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

4. Hilton Rochester Mayo Clinic Area

5. Residence Inn by Marriott Rochester Mayo Clinic Area South

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

7. The Berkman

8. Staybridge Suites Rochester - Mayo Clinic Area by IHG

9. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

10. Hyatt House Rochester/Mayo Clinic Area

11. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

12. Candlewood Suites Rochester Mayo Clinic Area by IHG

13. Broadway Plaza, Trademark Collection by Wyndham

14. Hampton Inn Rochester-South

15. Aspen Suites

16. Hotel Indigo Rochester – Mayo Clinic Area by IHG

17. Quality Inn & Suites Mayo Clinic Area

18. Hilton Garden Inn Rochester Downtown, MN

19. Brentwood Inn & Suites

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Compare popular hotels close to Mayo Clinic Hospital - Saint Marys Campus

Top Mayo Clinic Hospital - Saint Marys Campus Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Brentwood Inn & Suites

Aspen Select

TownePlace Suites by Marriott Rochester Mayo Clinic Area

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hyatt House Rochester/Mayo Clinic Area

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Frequently asked questions

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