𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Wykoff from RM273 (2026) - Fully Refundable Options

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Our top choices for Wykoff hotels

A lobby with leather sofas, a reception desk, a clock, and a map of the museum.

A large, single-story motel with a covered parking area and a grassy lawn.

A hotel room with a large bed, a separate bathroom with a bathtub, a bedside table with a lamp, and a framed picture on the wall.

A breakfast room with wooden tables and chairs, a coffee machine, and a view of the outdoors.

1. Americas Best Value Inn & Suites Spring Valley

Spring Valley

Lori

RM363

RM401 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with two beds, a desk, a chair, and a lamp.

A living room with a brick fireplace, two armchairs with decorative pillows, and a framed map on the wall.

A hotel lobby with a dining area, a fireplace, and a television displaying a map.

A lobby with a checkered floor, two blue armchairs, a table with a lamp, and a 'WELCOME' sign.

2. Country Trails Inn & Suites

Preston

Jeannie

RM516

RM570 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor seating area with wicker chairs and tables, surrounded by vibrant flowers and a red umbrella.

A spacious living area with a high ceiling, wooden beams, a blue armchair, a sofa, and a glass coffee table.

A bedroom with a large bed, a bathtub, a wooden rocking chair, and a desk with a lamp.

A cozy living room with a fireplace, a staircase, and a dining area.

3. Stone Mill Hotel & Suites

Lanesboro

Jenifer

RM429

RM460 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, a desk with a chair, a window with a view of the outdoors, and two bedside lamps.

A laundry area with two Whirlpool washers and a dryer, a wooden shelf above, and a white ceiling.

A Comfort Inn & Suites hotel with a blue facade, multiple windows, and a parking lot.

A reception desk with a wooden finish, a large illuminated 'C' sign, and a modern light fixture on the ceiling.

4. Comfort Inn & Suites Rochester South Mayo Clinic

Rochester

Phil

RM316

RM364 total

includes taxes & fees

15 Nov - 16 Nov

A multi-story building with a balcony, surrounded by various potted plants and flowers.

A porch with a variety of potted plants and flowers, a sign reading "OFFICE Welcome to Green Gables," and a door with a green doorbell.

An outdoor patio with tables and chairs, green umbrellas, and a wooden deck.

A bedroom with a four-poster bed, a sofa, a desk, and a fireplace.

5. Green Gables Inn

Lanesboro

Gary

RM410

RM440 total

includes taxes & fees

19 Oct - 20 Oct

A modern hotel lobby with a reception desk, seating area, and a kitchenette.

A small, well-organized pantry with shelves stocked with snacks and beverages.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

A hotel with a covered entrance, multiple floors, and a parking lot.

6. Spark by Hilton Rochester South

Rochester

Stanton

RM309

RM356 total

includes taxes & fees

29 Oct - 30 Oct

A reception desk with a wooden finish, a glass partition, and a blue wall with climbing plants.

A hotel room with two beds, each with white linens and patterned bedspreads. There are bedside tables with lamps, a desk with a chair, and a wall-mounted TV.

A dining area with wooden tables and chairs, a brick fireplace, and a television mounted above it.

A staircase with patterned carpet and wooden handrails leading to a door marked with the number 201.

7. America's Stay Inn Stewartville

Stewartville

Robert

RM257

RM288 total

includes taxes & fees

12 Nov - 13 Nov

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern bar area with seating and a counter.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

A modern indoor pool area with lounge chairs and a pool.

8. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

Elsie

RM482

RM555 total

includes taxes & fees

23 Oct - 24 Oct

A modern hotel lobby with a reception desk, seating area, and a dining space.

A hotel room with a bed, desk, chair, and a bathroom.

A modern breakfast area with a counter displaying various food items, a water dispenser, and a sign indicating a bakery section.

A modern hotel room with a wooden desk, orange chair, dark sofa, and a small table.

9. Holiday Inn Express Rochester South - Mayo Area by IHG

Rochester

Melissa

RM367

RM423 total

includes taxes & fees

15 Nov - 16 Nov

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

A modern hotel with a flat roof, multiple windows, and a covered outdoor seating area.

A modern lounge area with seating, a fireplace, and a bar area.

10. Residence Inn by Marriott Rochester Mayo Clinic Area South

Rochester

Chee

RM563

RM649 total

includes taxes & fees

8 Nov - 9 Nov

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern lounge area with a sofa, chairs, and tables.

A modern hotel room with a bed, desk, and kitchenette.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

11. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

howard

RM483

RM556 total

includes taxes & fees

12 Nov - 13 Nov

A modern indoor patio with a fire feature, seating, and large windows.

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

12. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

James

RM465

RM544 total

includes taxes & fees

17 Oct - 18 Oct

A spacious outdoor dining area with modern furniture and large windows offering views of the city.

A modern hotel room with a large bed, a sofa, a small table, a desk, and a wardrobe.

A modern interior with a wooden ceiling, a large black shelving unit, and a refrigerator stocked with beverages.

A reception desk with a modern design, featuring a wooden panel and a wall adorned with framed botanical artwork.

13. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

Hernan

RM421

RM484 total

includes taxes & fees

13 Nov - 14 Nov

A La Quinta Inn & Suites hotel with a well-lit entrance, a parking area, and a clear view of the building's facade.

A modern lobby with a teal sofa, yellow chairs, a small round table, and a fireplace with a TV.

A hotel reception area with wooden reception desks, a cityscape mural on the wall, and a check-in counter with a bookshelf.

A buffet counter with a variety of food items, a coffee station, and a beverage dispenser.

14. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Rochester

Alvaro

RM292

RM336 total

includes taxes & fees

8 Nov - 9 Nov

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

15. Hampton Inn Rochester-South

Rochester

dennis

RM448

RM515 total

includes taxes & fees

12 Nov - 13 Nov

A coffee shop interior with a wooden counter, menu boards, and seating area.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

16. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park

Cory

RM559

RM644 total

includes taxes & fees

24 Oct - 25 Oct

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

A modern kitchen with a microwave, coffee maker, and a dining area with a white table and chairs.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

17. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park

Sheri

RM466

RM544 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

18. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park

Jon

RM511

RM588 total

includes taxes & fees

23 Oct - 24 Oct

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

A hotel room with a blue sofa, a wooden bench, a small table with a lamp, a painting of a flower, and a kitchenette in the background.

A reception area with two counters, a patterned wall, and a wooden floor.

A spacious lobby with a large seating area, a fireplace, and large windows providing natural light.

19. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester

Richard

RM482

RM555 total

includes taxes & fees

24 Oct - 25 Oct

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A garden with a water feature, rocks, and yellow umbrellas.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A restaurant interior with wooden tables, chairs, and a stone wall.

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest

Christine

RM466

RM537 total

includes taxes & fees

17 Oct - 18 Oct

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Stay near popular Wykoff attractions

Ed's Museum

You can spend time browsing the exhibits at Ed's Museum during your travels in Wykoff. Discover the countryside while you're in the area.

See properties

Top Wykoff Hotel Reviews

Brentwood Inn & Suites

10/10 Excellent

"Everyone was very helpful even the guests. Breakfast was good. Parking was great."

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"We enjoyed our stay. We will be staying there approximately 7 days when my husband has surgery next week."

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

10/10 Excellent

"'staff was very good"

Aspen Select

10/10 Excellent

"Great"

Holiday Inn Express Rochester South - Mayo Area by IHG

10/10 Excellent

"clean room helpful staff comfortable bed"

Hampton Inn Rochester-South

10/10 Excellent

"Have stayed here numerous times and always had a great stay. Pool water is comfortable, like the soup at 6 pm and great breakfasts."

Hotel Indigo Rochester – Mayo Clinic Area by IHG

8/10 Good

"We checked in at 8:30 p.m. When we got close to our room, the cleaning carts were in the way. We moved them. At 9:25, the sweeper started next door. We retired early and were in bed. Loud! The shuttle service is super. Asked for a invoice and could not get one. Would use this again because of the location."

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"the shuttle to the mayo was great however you have to plan for at least 1 hr for the return trip. The down fall is that so many people in Rochester going to the mayo may be in a wheelchair, like myself and a very rare amount of shuttles form hotels are handicap accessible. This hotel work because I did not join my husband."

Med City Inn & Suites - Mayo Clinic Area

8/10 Good

"Perfect location for me."

More cheap stays in Wykoff

Birch Hill Suite Rochester – Med City

3595 Commercial Drive SW Rochester MN

RM237

RM273 total

18 Oct - 19 Oct

includes taxes & fees

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

RM309

RM355 total

19 Oct - 20 Oct

includes taxes & fees

7.8/10 Good! (1,030 reviews)

Comfort Inn & Suites Rochester South Mayo Clinic

7320 Airport View Dr Sw Rochester MN

RM316

RM364 total

15 Nov - 16 Nov

includes taxes & fees

8.8/10 Excellent! (1,005 reviews)

Holiday Inn Express Rochester South - Mayo Area by IHG

4141 Maine Avenue SE Rochester MN

RM367

RM423 total

15 Nov - 16 Nov

includes taxes & fees

8.8/10 Excellent! (1,001 reviews)

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN

RM386

RM445 total

19 Oct - 20 Oct

includes taxes & fees

8.2/10 Very good! (1,001 reviews)

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN

RM510

RM588 total

5 Nov - 6 Nov

includes taxes & fees

8.8/10 Excellent! (1,005 reviews)

Frequently asked questions

Where is the best place to stay in Wykoff?

Located 22.4 mi (36.1 km) from the heart of Wykoff, AmericInn by Wyndham Rochester Near Mayo Clinic is a top choice for your stay, based on our traveller data. Two other choices for your trip to the area are Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in Wykoff.

If I need to cancel my hotel reservation in Wykoff, will I receive a refund?

Yes! You'll find that most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Wykoff.

How is it staying in Wykoff?

Visitors can enjoy all that Wykoff has to offer, including its museums. There are 321 hotels and other accommodation options in the surrounding area. Find out more about Wykoff.

What should I see while I'm in Wykoff?

A favourite place to visit is Ed's Museum. You'll also find Forestville Mystery Cave State Park and Four Daughters Vineyard & Winery in the area. Take a look at what more there is to see and do in Expedia's Wykoff guide.

What's the weather like in Wykoff?

The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -5°C. The snowiest months in Wykoff are January, March, February and April, with each month seeing an average of 20 cm of snowfall.

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Car hire near State Orphanage Museum

Wykoff hotels from RM273

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Wykoff

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Wykoff hotels

1. Americas Best Value Inn & Suites Spring Valley

2. Country Trails Inn & Suites

3. Stone Mill Hotel & Suites

4. Comfort Inn & Suites Rochester South Mayo Clinic

5. Green Gables Inn

6. Spark by Hilton Rochester South

7. America's Stay Inn Stewartville

8. Hyatt House Rochester/Mayo Clinic Area

9. Holiday Inn Express Rochester South - Mayo Area by IHG

10. Residence Inn by Marriott Rochester Mayo Clinic Area South

11. Home2 Suites by Hilton Rochester Mayo Clinic Area

12. EVEN Hotel Rochester - Mayo Clinic Area by IHG

13. Hotel Indigo Rochester – Mayo Clinic Area by IHG

14. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

15. Hampton Inn Rochester-South

16. TownePlace Suites by Marriott Rochester Mayo Clinic Area

17. Staybridge Suites Rochester - Mayo Clinic Area by IHG

18. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

19. Hilton Garden Inn Rochester Downtown, MN

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Stay near popular Wykoff attractions

Ed's Museum

Top Wykoff Hotel Reviews

Brentwood Inn & Suites

Kahler Inn and Suites - Mayo Clinic Area

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Aspen Select

Holiday Inn Express Rochester South - Mayo Area by IHG

Hampton Inn Rochester-South

Hotel Indigo Rochester – Mayo Clinic Area by IHG

AmericInn by Wyndham Rochester Near Mayo Clinic

Med City Inn & Suites - Mayo Clinic Area

More cheap stays in Wykoff

Birch Hill Suite Rochester – Med City

Med City Inn & Suites - Mayo Clinic Area

Comfort Inn & Suites Rochester South Mayo Clinic

Holiday Inn Express Rochester South - Mayo Area by IHG

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Brentwood Inn & Suites

Frequently asked questions

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