A calm body of water, a sandy beach, and a forested area in the distance.

Cape Girardeau Spa Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Cape Girardeau Hotels with Spa

Our top choices for Cape Girardeau hotels with a spa

1. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (562 reviews)
"The Cape Girardeau Marriott is the best hotel to stay at"
United States
Chris
The price is RM474
RM537 total
includes taxes & fees
29 Nov - 30 Nov
Courtyard by Marriott Cape Girardeau Downtown

2. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (704 reviews)
"Every time I stay here I truly enjoy my stay Clean rooms and staff is very attentive Will stay here again"
United States
Irvin
The price is RM466
RM526 total
includes taxes & fees
15 Nov - 16 Nov
The Riverview

3. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,005 reviews)
"Easy check in and room was very clean. The food for breakfast and dinner is the bomb."
United States
Melody
The price is RM408
RM460 total
includes taxes & fees
15 Nov - 16 Nov
Drury Plaza Hotel Cape Girardeau Conference Center

4. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Clean, spacious suite, enjoyable kick back and breakfast!"
United States
Mary
The price is RM367
RM414 total
includes taxes & fees
19 Nov - 20 Nov
Drury Inn & Suites Cape Girardeau

5. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (861 reviews)
"Staff was friendly and helpful. Rooms and facilities were clean."
United States
Britney
The price is RM398
RM449 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn Cape Girardeau I 55 East

6. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (242 reviews)
"Everything is very clean. Excellent facility all around. Friendly staff"
United States
Dane
The price is RM350
RM395 total
includes taxes & fees
29 Nov - 30 Nov
Fairfield Inn & Suites by Marriott Cape Girardeau

7. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Perfect location, beds were awesome & staff were friendly & accommodating!"
United States
Rebecca
The price is RM388
RM442 total
includes taxes & fees
13 Dec - 14 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

8. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (201 reviews)
"Had a great stay friendly staff very clean facilities!"
United States
Shannon
The price is RM348
RM396 total
includes taxes & fees
23 Nov - 24 Nov
Tru By Hilton Cape Girardeau

9. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,004 reviews)
"The lady's that works there are wonderful, and of course the breakfast was amazing!!"
United States
Livia
The price is RM294
RM331 total
includes taxes & fees
22 Nov - 23 Nov
Pear Tree Inn Cape Girardeau West

10. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (1,001 reviews)
"Nice clean room"
United States
James
The price is RM282
RM340 total
includes taxes & fees
26 Nov - 27 Nov
Candlewood Suites Cape Girardeau by IHG

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.0 out of 10, Good, (823 reviews)
"Clean rooms, nice staff"
United States
Dayanita
The price is RM242
RM273 total
includes taxes & fees
22 Nov - 23 Nov
Quality Inn Cape Girardeau North

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, (244 reviews)
"Room was clean, bed was comfortable, staff was friendly, parking was easy. It was an older hotel and could use some renovation but would definitely stay again."
United States
Jaime
The price is RM286
RM334 total
includes taxes & fees
17 Nov - 18 Nov
Town House Inn Cape Giradreau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Cape Girardeau

Top Cape Girardeau Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Cape Girardeau?
Treat yourself to some pampering and book a hotel with a spa. Travellers recommend the gourmet restaurants in Cape Girardeau. Enjoy the historical sites and riverfront during your holiday. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness centre.
How many spa hotels will I find in Cape Girardeau?
Among Expedia's 69 accommodation options in Cape Girardeau, there is 1 spa hotel.
What's there to see and do in Cape Girardeau?
Experience all that Cape Girardeau has to offer when you visit Century Casino & Hotel Cape Girardeau, Show Me Center and Hunter Valley Winery. If you have a bit of extra time while you're in the area, you might want to check out Trail of Tears State Park and Shawnee National Forest.
What is a Cape Girardeau spa hotel?
Spa hotels in Cape Girardeau have full on-site spas offering services including massages and a selection of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation and relaxation.

Explore a world of travel with Expedia