A calm body of water, a sandy beach, and a forested area in the distance.

Cape Girardeau Spa Hotels

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Check availability on Cape Girardeau Hotels with Spa

Tonight
29 Sept - 30 Sept
Tomorrow
30 Sept - 1 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Cape Girardeau hotels with a spa

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
RM404
RM460 total
includes taxes & fees
29 Oct - 30 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
View all properties

Choose what matters most at spa hotels in Cape Girardeau

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Cape Girardeau Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Upgraded to a 2 room suite. Rey nice room lots of storage. Would definitely stay here again."
Christy 2-night trip
Posted 2 days ago
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

10/10 Excellent
"We had such a wonderful stay at this hotel! The entire property was very clean and well cared for. You could really tell that they take pride in keeping the rooms and common areas in great condition. The staff were incredibly friendly, welcoming, and personable, which made us feel right at home. The breakfast was delicious, with everything kept fresh and clean. My three kids also enjoyed spending time in the pool, and I was impressed by how spotless and well maintained the pool area was as well. Overall, we had a fantastic stay. Everything was comfortable, clean, and welcoming, it truly felt like a home away from home. We would definitely stay here again!"
Joann 1-night trip
Posted 3 days ago
Drury Inn & Suites Jackson MO

Frequently asked questions

Looking for a spa hotel in Cape Girardeau?
Treat yourself to some pampering and book a hotel with a spa. Travellers recommend the gourmet restaurants in Cape Girardeau. Enjoy the historical sites and riverfront during your holiday. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness centre.
How many spa hotels will I find in Cape Girardeau?
Among Expedia's 69 accommodation options in Cape Girardeau, there is 1 spa hotel.
What's there to see and do in Cape Girardeau?
Experience all that Cape Girardeau has to offer when you visit Century Casino & Hotel Cape Girardeau, Show Me Center and Hunter Valley Winery. If you have a bit of extra time while you're in the area, you might want to check out Trail of Tears State Park and Shawnee National Forest.
What is a Cape Girardeau spa hotel?
Spa hotels in Cape Girardeau have full on-site spas offering services including massages and a selection of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation and relaxation.

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