A calm body of water, a sandy beach, and a forested area in the distance.

Cape Girardeau hotels from RM273

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Check prices for these dates

Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov

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Our top choices for Cape Girardeau hotels

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,005 reviews)
"Easy check in and room was very clean. The food for breakfast and dinner is the bomb."
United States
Melody
The price is RM408
RM460 total
includes taxes & fees
15 Nov - 16 Nov
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Perfect location, beds were awesome & staff were friendly & accommodating!"
United States
Rebecca
The price is RM388
RM442 total
includes taxes & fees
13 Dec - 14 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

3. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Clean, spacious suite, enjoyable kick back and breakfast!"
United States
Mary
The price is RM367
RM414 total
includes taxes & fees
19 Nov - 20 Nov
Drury Inn & Suites Cape Girardeau
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

4. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (861 reviews)
"Staff was friendly and helpful. Rooms and facilities were clean."
United States
Britney
The price is RM398
RM449 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn Cape Girardeau I 55 East
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

5. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (704 reviews)
"Every time I stay here I truly enjoy my stay Clean rooms and staff is very attentive Will stay here again"
United States
Irvin
The price is RM466
RM526 total
includes taxes & fees
15 Nov - 16 Nov
The Riverview
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

6. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (242 reviews)
"Everything is very clean. Excellent facility all around. Friendly staff"
United States
Dane
The price is RM350
RM395 total
includes taxes & fees
29 Nov - 30 Nov
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with marble flooring, elegant seating, and a grand staircase.

7. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (562 reviews)
"The Cape Girardeau Marriott is the best hotel to stay at"
United States
Chris
The price is RM474
RM537 total
includes taxes & fees
29 Nov - 30 Nov
Courtyard by Marriott Cape Girardeau Downtown
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

8. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,004 reviews)
"The lady's that works there are wonderful, and of course the breakfast was amazing!!"
United States
Livia
The price is RM294
RM331 total
includes taxes & fees
22 Nov - 23 Nov
Pear Tree Inn Cape Girardeau West
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (201 reviews)
"Had a great stay friendly staff very clean facilities!"
United States
Shannon
The price is RM348
RM396 total
includes taxes & fees
23 Nov - 24 Nov
Tru By Hilton Cape Girardeau
A hotel room with a kitchenette, a bed, a desk, and a TV.

10. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (1,001 reviews)
"Nice clean room"
United States
James
The price is RM282
RM340 total
includes taxes & fees
26 Nov - 27 Nov
Candlewood Suites Cape Girardeau by IHG
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.0 out of 10, Good, (823 reviews)
"Clean rooms, nice staff"
United States
Dayanita
The price is RM242
RM273 total
includes taxes & fees
22 Nov - 23 Nov
Quality Inn Cape Girardeau North
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, (244 reviews)
"Room was clean, bed was comfortable, staff was friendly, parking was easy. It was an older hotel and could use some renovation but would definitely stay again."
United States
Jaime
The price is RM286
RM334 total
includes taxes & fees
17 Nov - 18 Nov
Town House Inn Cape Giradreau
A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a landscaped entrance area.

13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (897 reviews)
"Very clean and every one very nice and helpful"
United States
richard
The price is RM326
RM353 total
includes taxes & fees
16 Nov - 17 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

14. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,001 reviews)
"The hotel was clean, comfortable and the breakfast was good."
United States
Leonardo
The price is RM326
RM345 total
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites Jackson MO
A building with a sign reading "Comfort Suites."

15. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.0 out of 10, Very good, (785 reviews)
"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"
United States
Jeff
The price is RM308
RM333 total
includes taxes & fees
13 Dec - 14 Dec
Comfort Suites Jackson-Cape Girardeau
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

16. Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (451 reviews)
"Great owners "
United States
Jennifer
The price is RM323
RM350 total
includes taxes & fees
15 Nov - 16 Nov
Town House Inn
A brick building with a sign reading "Mercantile & Hotel".

17. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (118 reviews)
"Awesome hotel and staff was first rate, everything was fantastic. If you are in the area, stay at this hotel and eat in!!"
United States
Jan
The price is RM429
RM467 total
includes taxes & fees
15 Nov - 16 Nov
EC Reed's Mercantile and Hotel
A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.

18. Makanda Inn

Makanda Inn
3.5 star property
Makanda
10.0 out of 10, Exceptional, (41 reviews)
"Makanda inn is a very well maintained place. The room was very comfortable, and the staff was excellent. The breakfasts were delicious."
United States
Thomas
The price is RM1,069
RM1,218 total
includes taxes & fees
15 Nov - 16 Nov
Makanda Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Hotels recommended for families in Cape Girardeau

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000)
The price is RM367
RM414 total
includes taxes & fees
19 Nov - 20 Nov
Drury Inn & Suites Cape Girardeau
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Stay near popular Cape Girardeau attractions

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

See all hotels in Cape Girardeau
A nighttime view of a bridge with its cables illuminated against a starry sky.

Top Cape Girardeau Hotel Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

8/10 Good
"Its nice"
Alexis 1-night trip
Posted 11 hours ago
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

More cheap stays in Cape Girardeau

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO
The price is RM242 per night from 22 Nov to 23 Nov
RM242
RM273 total
22 Nov - 23 Nov
includes taxes & fees

Frequently asked questions

What's the best place to stay in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is one of the top choices for your stay based on our traveller data. This hotel offers free breakfast and a restaurant. Other good options for your visit include The Riverview and Pear Tree Inn Cape Girardeau West. See all available top hotels, or vacation rentals in Cape Girardeau.
If I need to cancel my hotel reservation in Cape Girardeau, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Cape Girardeau.
What's the best accommodation for a budget-friendly stay in Cape Girardeau?
Based on reviews, Pear Tree Inn Cape Girardeau West is a popular hotel for our travellers who want a more economical choice, and features free buffet breakfast and free Wi-Fi. View all budget hotels in Cape Girardeau.
What's the best family accommodation in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Pear Tree Inn Cape Girardeau West is another good option for your stay with the kids. Also, attractions such as Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are fun for children of all ages. Find more child-friendly accommodations in Cape Girardeau.
What's the best LGBTQ-friendly hotel in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Candlewood Suites Cape Girardeau by IHG and Pear Tree Inn Cape Girardeau West are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Cape Girardeau.
What's the best dog-friendly hotel in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include Candlewood Suites Cape Girardeau by IHG and Pear Tree Inn Cape Girardeau West. See more pet-friendly hotel accommodations in Cape Girardeau.
What are some accommodation options with pools in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top hotel with a pool, a full-service spa and free WiFi. View all hotels with pools in Cape Girardeau.
What is the best spa hotel in Cape Girardeau?
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness centre. See all spa hotels in Cape Girardeau.
What is staying in Cape Girardeau like?
History buffs will enjoy exploring Cape Girardeau, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its riverfront, university setting and shopping. In Cape Girardeau, there are 69 hotels and other accommodation options to choose from. Find out more about Cape Girardeau.
What should I do while I'm visiting Cape Girardeau?
Favorite family attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. Landmarks like The Glenn House and Fort D Historic Site might be worth a visit. The picturesque setting of Shawnee National Forest and Mississippi River exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Cape Girardeau guide.
What's the weather like in Cape Girardeau?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.

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