𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Cape Girardeau from RM275 (2026) - Fully Refundable Options

A calm body of water, a sandy beach, and a forested area in the distance.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Cape Girardeau

Pet friendly

Pool

Apartment

Family friendly

Waterpark

Condo

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Cape Girardeau hotels

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

RM404

RM460 total

includes taxes & fees

29 Oct - 30 Oct

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

2. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

RM407

RM460 total

includes taxes & fees

4 Oct - 5 Oct

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

3. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

RM413

RM466 total

includes taxes & fees

8 Oct - 9 Oct

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

An outdoor patio with stone walls, wicker furniture, and large windows.

4. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

RM431

RM486 total

includes taxes & fees

8 Oct - 9 Oct

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

5. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Teresa

RM371

RM419 total

includes taxes & fees

5 Oct - 6 Oct

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

6. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Elizabeth

RM293

RM331 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A hotel room with two beds, a desk, a chair, and a view of the city.

7. The Riverview

Cape Girardeau

Alyssa

RM467

RM526 total

includes taxes & fees

30 Sept - 1 Oct

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

A lobby with seating areas, a reception desk, and a bar.

A spacious living room with a sofa set, a coffee table, and a dining area.

8. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

RM510

RM578 total

includes taxes & fees

8 Oct - 9 Oct

A modern retail area with a display of local items and snacks.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

9. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

RM364

RM414 total

includes taxes & fees

5 Oct - 6 Oct

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel room with a bed, a TV, a desk, and a chair.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

10. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

RM347

RM414 total

includes taxes & fees

11 Oct - 12 Oct

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

11. Quality Inn Cape Girardeau North

Cape Girardeau

Danny

RM244

RM275 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

A bathroom with a marble wall and a white bathtub.

12. Town House Inn Cape Giradreau

Cape Girardeau

Joshua

RM306

RM357 total

includes taxes & fees

1 Oct - 2 Oct

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A hotel room with two beds, a nightstand, a lamp, and a chair.

13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

RM343

RM371 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

A hotel room with two beds, a brick wall, and a wooden headboard.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

14. Drury Inn & Suites Jackson MO

Jackson

Thomas

RM342

RM362 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

15. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

RM313

RM338 total

includes taxes & fees

22 Oct - 23 Oct

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

16. Town House Inn

Jackson

Taylor

RM291

RM315 total

includes taxes & fees

30 Sept - 1 Oct

A living room with a blue wall, a fireplace, a sofa, and a chair.

A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

A brick building with a sign reading "Mercantile & Hotel".

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

17. EC Reed's Mercantile and Hotel

Marble Hill

JANEEN

RM428

RM466 total

includes taxes & fees

25 Oct - 26 Oct

A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.

A rustic building with a thatched roof, surrounded by dense greenery and a gravel path leading to it.

A cozy log cabin interior with a wooden staircase, a cushioned sofa, a small table, and a lamp.

A cozy living room with a brown leather sofa, a wooden coffee table, and a window with a view of trees.

18. Makanda Inn

Makanda

Michele

RM1,069

RM1,219 total

includes taxes & fees

30 Sept - 1 Oct

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Cape Girardeau attractions

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)

Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.

See properties

A cable-stayed bridge over a river with a rocky shoreline in the foreground.

Riverfront Bridge Park

8.8/10 (129 reviews)

Enjoy panoramic views of the Mississippi River and Bill Emerson Memorial Bridge from this peaceful riverside park. Stroll along the well-maintained walking paths and find perfect spots for memorable photographs.

See properties

Century Casino & Hotel Cape Girardeau

8.4/10 (176 reviews)

Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your time in Cape Girardeau? While in this family-friendly area, you can savour the top-notch restaurants.

See properties

Hunter Valley Winery

7.4/10 (48 reviews)

Sip award-winning Chambourcin and Chardonnay at this picturesque Missouri estate with lake views. Bring a picnic basket and enjoy live weekend music on the deck overlooking the sculpture garden.

See properties

Riverfront Park

8.0/10 (2 reviews)

This riverside haven features terraced seating overlooking the Mississippi and a flood wall adorned with historical murals. Stroll the riverfront trail while watching paddle boats dock at this picturesque park.

See properties

Show Me Center

8.6/10 (40 reviews)

The Show Me Centre hosts Southeast Missouri State basketball and major concerts in a versatile arena setting. Catch Redhawks games or enjoy performances by renowned artists in this regional entertainment hub.

See properties

Cape Splash Family Aquatic Center

8.6/10 (21 reviews)

This 3.5-acre water park thrills with a 265-foot free-fall slide and 700-foot lazy river. Families can splash in the pirate ship playground or relax in shaded lounge areas during summer months.

See properties

eDen Spa & Salon

7.8/10 (25 reviews)

Cape Girardeau's only AVEDA Concept spa resides in a historic 1800s Colonial home blending antique charm with modern amenities. Book a massage or facial and arrive early to enjoy the infrared sauna before your treatment.

See properties

Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

See all hotels in Cape Girardeau

A nighttime view of a bridge with its cables illuminated against a starry sky.

Top Cape Girardeau Hotel Reviews

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"trodo estubo excelente gracias por sus servicios"

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"The room was very clean and the bed was very comfortable. The parking around the hotel was ample and the amenities were great. So many stores and restaurants within walking distance. The breakfast was the best with home cooked eggs and gravy."

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Clean rooms. Nice breakfast. Very nice staff."

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Upgraded to a 2 room suite. Rey nice room lots of storage. Would definitely stay here again."

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."

Drury Inn & Suites Jackson MO

10/10 Excellent

"We had such a wonderful stay at this hotel! The entire property was very clean and well cared for. You could really tell that they take pride in keeping the rooms and common areas in great condition. The staff were incredibly friendly, welcoming, and personable, which made us feel right at home. The breakfast was delicious, with everything kept fresh and clean. My three kids also enjoyed spending time in the pool, and I was impressed by how spotless and well maintained the pool area was as well. Overall, we had a fantastic stay. Everything was comfortable, clean, and welcoming, it truly felt like a home away from home. We would definitely stay here again!"

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

EC Reed's Mercantile and Hotel

8/10 Good

"Very cute and clean room. The hotel was quaint, but the lay out was a little strange. Everything was ready and convenient for us when we arrived to check-in. The process was just as easy to check-out. Never had to communicate anything to staff. It was a contract-less transaction. But very clear if any thing was needed that were able to contact someone for immediate assistance. I actually loved the quaintness. The only thing that was an issue, were the doors need adjusting because they would stick and they were hard to pull open. I would definitely stay there again. Even with the hard to open doors."

Quality Inn Cape Girardeau North

8/10 Good

"No complaints"

More cheap stays in Cape Girardeau

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

RM244

RM275 total

11 Oct - 12 Oct

includes taxes & fees

7/10 Good! (800 reviews)

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

RM293

RM331 total

4 Oct - 5 Oct

includes taxes & fees

9.2/10 Wonderful! (1,007 reviews)

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

RM347

RM414 total

11 Oct - 12 Oct

includes taxes & fees

8/10 Very good! (1,002 reviews)

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

RM364

RM414 total

5 Oct - 6 Oct

includes taxes & fees

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

RM404

RM460 total

29 Oct - 30 Oct

includes taxes & fees

Hotel 7 Inn Anna

100 Richview Dr Anna IL

Get rates

6.6/10 (244 reviews)

Frequently asked questions

What's the best place to stay in Cape Girardeau?

Drury Plaza Hotel Cape Girardeau Conference Center is one of the top choices for your stay based on our traveller data. This hotel offers free breakfast and a restaurant. Other good options for your visit include The Riverview and Pear Tree Inn Cape Girardeau West. See all available top hotels, or vacation rentals in Cape Girardeau.

If I need to cancel my hotel reservation in Cape Girardeau, will I receive a refund?

Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Cape Girardeau.

What's the best accommodation for a budget-friendly stay in Cape Girardeau?

Based on reviews, Pear Tree Inn Cape Girardeau West is a popular hotel for our travellers who want a more economical choice, and features free buffet breakfast and free Wi-Fi. View all budget hotels in Cape Girardeau.

What's the best family accommodation in Cape Girardeau?

Drury Plaza Hotel Cape Girardeau Conference Center is a hotel with an indoor pool and a restaurant, and it's a top choice on Expedia for families. Pear Tree Inn Cape Girardeau West is another good option for your stay with the kids. Also, attractions such as Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are fun for children of all ages. Find more child-friendly accommodations in Cape Girardeau.

What's the best LGBTQ-friendly hotel in Cape Girardeau?

Drury Plaza Hotel Cape Girardeau Conference Center is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Candlewood Suites Cape Girardeau by IHG and Pear Tree Inn Cape Girardeau West are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Cape Girardeau.

What's the best dog-friendly hotel in Cape Girardeau?

Drury Plaza Hotel Cape Girardeau Conference Center is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include Candlewood Suites Cape Girardeau by IHG and Pear Tree Inn Cape Girardeau West. See more pet-friendly hotel accommodations in Cape Girardeau.

What are some accommodation options with pools in Cape Girardeau?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top hotel with a pool, a full-service spa and free WiFi. View all hotels with pools in Cape Girardeau.

What is the best spa hotel in Cape Girardeau?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness centre. See all spa hotels in Cape Girardeau.

What is staying in Cape Girardeau like?

History buffs will enjoy exploring Cape Girardeau, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its riverfront, university setting and shopping. In Cape Girardeau, there are 69 hotels and other accommodation options to choose from. Find out more about Cape Girardeau.

What should I do while I'm visiting Cape Girardeau?

Favorite family attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. Landmarks like The Glenn House and Fort D Historic Site might be worth a visit. The picturesque setting of Shawnee National Forest and Mississippi River exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Cape Girardeau guide.

What's the weather like in Cape Girardeau?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.

Cape Girardeau hotels from RM275

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Cape Girardeau

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Cape Girardeau hotels

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2. Drury Plaza Hotel Cape Girardeau Conference Center

3. Fairfield Inn & Suites by Marriott Cape Girardeau

4. Hampton Inn Cape Girardeau I 55 East

5. Drury Inn & Suites Cape Girardeau

6. Pear Tree Inn Cape Girardeau West

7. The Riverview

8. Courtyard by Marriott Cape Girardeau Downtown

9. Tru By Hilton Cape Girardeau

10. Candlewood Suites Cape Girardeau by IHG

11. Quality Inn Cape Girardeau North

12. Town House Inn Cape Giradreau

13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

14. Drury Inn & Suites Jackson MO

15. Comfort Suites Jackson-Cape Girardeau

16. Town House Inn

17. EC Reed's Mercantile and Hotel

18. Makanda Inn

Stay near popular Cape Girardeau attractions

Southeast Missouri State University

Riverfront Bridge Park

Century Casino & Hotel Cape Girardeau

Hunter Valley Winery

Riverfront Park

Show Me Center

Cape Splash Family Aquatic Center

eDen Spa & Salon

Learn more about Cape Girardeau

Top Cape Girardeau Hotel Reviews

Candlewood Suites Cape Girardeau by IHG

Pear Tree Inn Cape Girardeau West

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Drury Inn & Suites Jackson MO

Courtyard by Marriott Cape Girardeau Downtown

EC Reed's Mercantile and Hotel

Quality Inn Cape Girardeau North

More cheap stays in Cape Girardeau

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

Tru By Hilton Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel 7 Inn Anna

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app