
Travel to Cape Girardeau
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Top hotels in Cape Girardeau

The Riverview
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is RM446 per night from 3 Aug to 4 Aug
RM446
RM503 total
3 Aug - 4 Aug
includes taxes & fees
9.2/10 Wonderful! (364 reviews)
"Beautiful spacious room."
Reviewed on 27 Jul 2025

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is RM381 per night from 4 Aug to 5 Aug
RM381
RM430 total
4 Aug - 5 Aug
includes taxes & fees
9.4/10 Exceptional! (1,016 reviews)
5 stars
"Hotel was extremely nice and comfortable. Unfortunately my family was unable to take advantage of the drinks and snacks in the lobby due to several youth volleyball teams also staying at the hotel. They took over the lobby and pool area and were so loud we couldn’t hear the hotel staff checking us ..."
Reviewed on 24 Jul 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is RM296 per night from 4 Aug to 5 Aug
RM296
RM334 total
4 Aug - 5 Aug
includes taxes & fees
8.8/10 Excellent! (1,009 reviews)
Super Facility Near The Medical Center!
"I have stayed at this Hotel several times when I have had early morning reporting times at St. Francis Medical Center. Each time it has been great. Friendly staff quiet atmosphere and great rooms with comfortable furnishings."
Reviewed on 29 Jul 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Cape Rock Park
Cape Rock Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants.
Hunter Valley Winery
You can enjoy a tasting or tour at Hunter Valley Winery during your travels to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Cape Girardeau Conservation Nature Center
Enjoy an outing to Cape Girardeau Conservation Nature Center during your stay in Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Frequently asked questions
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