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Hotels in South Main, Memphis

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Our top choices for South Main hotels

The Rambler

The Rambler
4.0 star property
South Main
9.2 out of 10, Wonderful, (523)
"Walkable, neat spot."
United States
Teresa
The price is RM541
RM651 total
includes taxes & fees
16 Dec - 17 Dec
The Rambler

The Central Station Memphis, Curio Collection by Hilton

The Central Station Memphis, Curio Collection by Hilton
4.0 star property
South Main
9.0 out of 10, Wonderful, (1004)
"Wonderful staff and ambiance "
United States
Gabriela
The price is RM458
RM552 total
includes taxes & fees
21 Dec - 22 Dec
The Central Station Memphis, Curio Collection by Hilton

Hotel Pontotoc

Hotel Pontotoc
2.0 star property
South Main
10.0 out of 10, Exceptional, (2)
"Beautiful hotel, great bar, spacious rooms. Excellent!!!"
United States
Cheryl
The price is RM856
RM1,017 total
includes taxes & fees
16 Dec - 17 Dec
Hotel Pontotoc

ARRIVE Memphis

ARRIVE Memphis
4.0 star property
South Main
9.6 out of 10, Exceptional, (1001)
"Great stay "
United States
LaKera
The price is RM717
RM860 total
includes taxes & fees
25 Dec - 26 Dec
ARRIVE Memphis

La Quinta Inn & Suites by Wyndham West Memphis

La Quinta Inn & Suites by Wyndham West Memphis
3.0 star property
11.3 km from South Main
8.6 out of 10, Excellent, (1004)
"The staff was super friendly!! Room was clean and breakfast was great!"
United States
Sheri
The price is RM341
RM394 total
includes taxes & fees
17 Dec - 18 Dec
La Quinta Inn & Suites by Wyndham West Memphis

Hu. Hotel

Hu. Hotel
3.5 star property
Downtown Memphis, 1.3 km from South Main
8.4 out of 10, Very good, (1619)
"Great hotel and location "
United States
Holiday
The price is RM359
RM446 total
includes taxes & fees
21 Dec - 22 Dec
Hu. Hotel

Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis
4.0 star property
Downtown Memphis, 0.7 km from South Main
8.8 out of 10, Excellent, (1404)
"Amazing hotel and staff and very convenient location to restaurants and shopping. "
United States
Timothy
The price is RM549
RM661 total
includes taxes & fees
21 Dec - 22 Dec
Hyatt Centric Beale Street Memphis

Hampton Inn & Suites Memphis-Beale Street

Hampton Inn & Suites Memphis-Beale Street
2.5 star property
Downtown Memphis, 0.9 km from South Main
8.6 out of 10, Excellent, (1231)
"Excellent hotel in a great location "
United States
Ralph
The price is RM456
RM549 total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Memphis-Beale Street

The Guest House at Graceland

The Guest House at Graceland
4.0 star property
Whitehaven, 10 km from South Main
9.4 out of 10, Exceptional, (2854)
"Large room, excellent staff and shuttle service was prompt and easy "
United States
cathy weaver
The price is RM894
RM1,144 total
includes taxes & fees
16 Dec - 17 Dec
The Guest House at Graceland

Canopy by Hilton Memphis Downtown

Canopy by Hilton Memphis Downtown
4.0 star property
Downtown Memphis, 1.1 km from South Main
8.6 out of 10, Excellent, (1002)
"Courteous staff, great location and walking distance to everything. Wining and dining. Food and ambience are superb. "
United States
Dennis
The price is RM470
RM567 total
includes taxes & fees
23 Dec - 24 Dec
Canopy by Hilton Memphis Downtown

Holiday Inn Express Memphis Medical Center Midtown by IHG

Holiday Inn Express Memphis Medical Center Midtown by IHG
2.5 star property
New Pathways, 3.3 km from South Main
8.6 out of 10, Excellent, (1004)
"Very friendly staff and rooms were spacious and clean."
United States
Douglas
The price is RM385
RM466 total
includes taxes & fees
19 Dec - 20 Dec
Holiday Inn Express Memphis Medical Center Midtown by IHG

Big Cypress Lodge

Big Cypress Lodge
5.0 star property
Pinch District, 2.3 km from South Main
9.0 out of 10, Wonderful, (1715)
"The lodge was amazing, we will be back soon."
United States
Carl
The price is RM938
RM1,204 total
includes taxes & fees
12 Jan - 13 Jan 2026
Big Cypress Lodge

voco Hotel Napoleon Memphis by IHG

voco Hotel Napoleon Memphis by IHG
4.0 star property
Downtown Memphis, 1.3 km from South Main
8.6 out of 10, Excellent, (977)
"The staff was very courteous. The room was clean and the bedding was very comfortable. Although my reason for staying here was to have a staycation and just relax in my room, the location of this property is great and very close to downtown attractions."
United States
Dimika
The price is RM520
RM626 total
includes taxes & fees
4 Jan - 5 Jan 2026
voco Hotel Napoleon Memphis by IHG

DoubleTree by Hilton Hotel Memphis

DoubleTree by Hilton Hotel Memphis
4.0 star property
East Memphis, 15.2 km from South Main
8.0 out of 10, Very good, (1002)
"Customer service was excellent"
United States
Denise
The price is RM477
RM575 total
includes taxes & fees
28 Dec - 29 Dec
DoubleTree by Hilton Hotel Memphis

La Quinta Inn & Suites by Wyndham Memphis Wolfchase

La Quinta Inn & Suites by Wyndham Memphis Wolfchase
3.0 star property
Wolfchase, 26.2 km from South Main
8.8 out of 10, Excellent, (1001)
"Clean room, friendly staff."
United States
James
The price is RM414
RM500 total
includes taxes & fees
18 Dec - 19 Dec
La Quinta Inn & Suites by Wyndham Memphis Wolfchase

Holiday Inn Southaven Central - Memphis by IHG

Holiday Inn Southaven Central - Memphis by IHG
4.0 star property
20.7 km from South Main
8.8 out of 10, Excellent, (920)
"Very nice rooms. Great for families. Clean and spacious. Several surrounding dining options and locations for shopping."
United States
Jon
The price is RM369
RM406 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Southaven Central - Memphis by IHG

Magnolia Inn And Suites

Magnolia Inn And Suites
2.0 star property
22.9 km from South Main
8.0 out of 10, Very good, (1001)
"Nice clean place for an overnight stay. "
United States
Zanetta
The price is RM287
RM330 total
includes taxes & fees
16 Dec - 17 Dec
Magnolia Inn And Suites

Hilton Garden Inn Memphis/Southaven, MS

Hilton Garden Inn Memphis/Southaven, MS
3.0 star property
20.4 km from South Main
8.6 out of 10, Excellent, (1005)
"Everything was great including the breakfast "
United States
Damien
The price is RM375
RM413 total
includes taxes & fees
22 Dec - 23 Dec
Hilton Garden Inn Memphis/Southaven, MS

The Westin Memphis Beale Street

The Westin Memphis Beale Street
4.0 star property
Downtown Memphis, 0.7 km from South Main
8.8 out of 10, Excellent, (1003)
"Room and location was very nice. "
United States
DEREX
The price is RM660
RM792 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Westin Memphis Beale Street

Tru by Hilton West Memphis, AR

Tru by Hilton West Memphis, AR
2.5 star property
9.9 km from South Main
8.6 out of 10, Excellent, (648)
"Staff was so welcoming and our stay was 10/10 experience will definitely be booking again. "
United States
Keyshelle
The price is RM374
RM432 total
includes taxes & fees
5 Jan - 6 Jan 2026
Tru by Hilton West Memphis, AR
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.

Downtown Memphis

Downtown Memphis is a destination visitors seek out for its ample dining options, fascinating museums and great live music. You might also want to check out attractions like Statue of Elvis or Orpheum Theatre while you're exploring the neighbourhood.

East Memphis

Travellers to East Memphis praise its popular shops. If you've got some more time to explore, be sure to stop by Leftwich Tennis Center and Theatre Memphis.

Midtown

Theatres, live music and museums are some highlights of Midtown. Make a stop by Minglewood Hall or Memphis Brooks Museum of Art while you're exploring.

Whitehaven

The ample dining options and great live music are top of the list for many visitors to Whitehaven. A stop by Graceland or Tri-State Bank of Memphis might round out your trip.

North Memphis

Visitors to North Memphis like its bars and churches, and Burkle Estate is a sight worth a stop.

Top South Main Hotel Reviews

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Frequently asked questions

What is South Main like?
You'll be sure to have fun exploring Memphis's South Main neighbourhood. Make sure that you visit Blues Hall of Fame Museum and Railroad & Trolley Museum as part of your South Main travel plans.
How many hotels can I expect to find in South Main?
Expedia has 47 hotels and other accommodation options in South Main to choose from, making this an ideal home base for exploring the greater Memphis area.
If I need to cancel my hotel reservation in South Main, will I receive a refund?
Yes! Most hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals available in South Main.
What are the top things to see and do in South Main?
Create some family memories with a visit to Blues Hall of Fame Museum or Railroad & Trolley Museum while you're in South Main. When you're sightseeing in Memphis, National Civil Rights Museum and Lorraine Motel are also worth a stop.
How can I get around South Main and the greater Memphis area?
To venture out of town, take a train from Memphis Central Station.