Hotels in South Main, Houston
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Our top choices for South Main hotels
Comfort Suites Houston near Medical Center- NRG Stadium
Comfort Suites Houston near Medical Center- NRG StadiumSouth Main
8.6 out of 10, Excellent, (1,003 reviews)
"Clean room, helpful staff and good location to hospital."
George
The price is RM366
RM428 total
includes taxes & fees
8 Feb - 9 Feb
Wingate Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical CenterSouth Main
6.6 out of 10, (1,003 reviews)
"Easy access to stadium "
Richard
The price is RM320
RM374 total
includes taxes & fees
4 Feb - 5 Feb
Quality Inn & Suites NRG Park - Medical Center
Quality Inn & Suites NRG Park - Medical CenterSouth Main
6.6 out of 10, (1,000 reviews)
"Everything was great"
Efrain
The price is RM273
RM319 total
includes taxes & fees
16 Feb - 17 Feb
Wyndham Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical CenterSouth Main
7.2 out of 10, Good, (1,211 reviews)
"Front desk staff was very professional and kind."
MARINA
The price is RM395
RM462 total
includes taxes & fees
3 Feb - 4 Feb
Candlewood Suites Houston Medical Center by IHG
Candlewood Suites Houston Medical Center by IHGSouth Main
7.4 out of 10, Good, (831 reviews)
"This is a safe, friendly hotel close to MDA Cancer Center"
Myra
The price is RM292
RM342 total
includes taxes & fees
5 Feb - 6 Feb
TownePlace Suites by Marriott Houston Intercontinental Arpt
TownePlace Suites by Marriott Houston Intercontinental Arpt30.6 km from South Main
9.0 out of 10, Wonderful, (699 reviews)
"Easy check-in, nice hotel, very clean, great location near IAH "
Steven
The price is RM376
RM447 total
includes taxes & fees
6 Feb - 7 Feb
Quality Suites Houston Hobby Airport
Quality Suites Houston Hobby AirportSoutheast Houston, 13.3 km from South Main
8.4 out of 10, Very good, (1,305 reviews)
"Super close to the airport, shuttle service was great, and room was clean!"
Adrianna
The price is RM244
RM286 total
includes taxes & fees
17 Feb - 18 Feb
Four Points by Sheraton Houston Intercontinental Airport
Four Points by Sheraton Houston Intercontinental Airport29.9 km from South Main
8.4 out of 10, Very good, (1,012 reviews)
"room was very comfortable and new modern looking
staff was great food was good i have stayed there 2 different nights so will recommend this place
shuttle to airport also good "
Raymond
The price is RM349
RM408 total
includes taxes & fees
20 Feb - 21 Feb
Hilton Garden Inn Houston/Bush Intercontinental Airport
Hilton Garden Inn Houston/Bush Intercontinental Airport31.1 km from South Main
8.4 out of 10, Very good, (1,003 reviews)
"It was a great stay "
Thrideep
The price is RM323
RM379 total
includes taxes & fees
20 Feb - 21 Feb
Holiday Inn Express & Suites Houston - Hobby Airport Area by IHG
Holiday Inn Express & Suites Houston - Hobby Airport Area by IHG16 km from South Main
8.4 out of 10, Very good, (1,004 reviews)
"Great place. "
Kay
The price is RM399
RM466 total
includes taxes & fees
23 Feb - 24 Feb
Doubletree by Hilton Houston Hobby Airport
Doubletree by Hilton Houston Hobby AirportSoutheast Houston, 14.5 km from South Main
8.8 out of 10, Excellent, (1,001 reviews)
"Super clean room with amazing cookies. "
Shannon
The price is RM418
RM493 total
includes taxes & fees
8 Feb - 9 Feb
Home2 Suites by Hilton Houston IAH Airport Beltway 8
Home2 Suites by Hilton Houston IAH Airport Beltway 829.9 km from South Main
8.4 out of 10, Very good, (806 reviews)
"Great room close to airport "
Kelli
The price is RM304
RM356 total
includes taxes & fees
22 Feb - 23 Feb
Hilton Houston North
Hilton Houston North30.5 km from South Main
8.4 out of 10, Very good, (1,003 reviews)
"Hilton always takes care of accommodations "
Donald
The price is RM482
RM564 total
includes taxes & fees
15 Feb - 16 Feb
Comfort Suites Westchase Houston Energy Corridor
Comfort Suites Westchase Houston Energy CorridorWestchase, 16.4 km from South Main
8.4 out of 10, Very good, (699 reviews)
"Very comfortable stay, nice rooms and incredible staff "
Austin
The price is RM223
RM301 total
includes taxes & fees
9 Feb - 10 Feb
Best Western Plus Houston Energy Corridor
Best Western Plus Houston Energy Corridor25.2 km from South Main
8.6 out of 10, Excellent, (1,005 reviews)
"Very clean, quiet, nice staff, nice breakfast, would stay here again!"
Mouna Keltoum
The price is RM302
RM353 total
includes taxes & fees
9 Feb - 10 Feb
Fairfield Inn & Suites Houston Intercontinental Airport
Fairfield Inn & Suites Houston Intercontinental Airport30.6 km from South Main
8.6 out of 10, Excellent, (1,001 reviews)
"Great place, nice room"
Lester
The price is RM332
RM395 total
includes taxes & fees
15 Feb - 16 Feb
Comfort Suites Near Sam Houston Race Park
Comfort Suites Near Sam Houston Race Park30.9 km from South Main
9.4 out of 10, Exceptional, (1,005 reviews)
"Always the best, we stay here every time we come to the race track"
Marilyn
The price is RM373
RM436 total
includes taxes & fees
5 Feb - 6 Feb
Best Western Plus Pearland/Houston Medical Center Hotel
Best Western Plus Pearland/Houston Medical Center HotelSoutheast Houston, 10.2 km from South Main
9.4 out of 10, Exceptional, (108 reviews)
"Clean comfortable and perfect for a business or family stay. "
Ziba
The price is RM338
RM395 total
includes taxes & fees
5 Feb - 6 Feb
Holiday Inn Express & Suites Houston IAH - Beltway 8 by IHG
Holiday Inn Express & Suites Houston IAH - Beltway 8 by IHG29.9 km from South Main
8.2 out of 10, Very good, (1,055 reviews)
"Great place to stay overnight. "
Raul
The price is RM300
RM351 total
includes taxes & fees
16 Feb - 17 Feb
Spark by Hilton Houston Bush Intercontinental Airport
Spark by Hilton Houston Bush Intercontinental Airport31.2 km from South Main
8.6 out of 10, Excellent, (1,001 reviews)
"Rooms were clean, front desk ladies were helpful and friendly. Very convenient to airport. "
Heidi
The price is RM434
RM508 total
includes taxes & fees
15 Feb - 16 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in South Main
Find the best South Main areas for the activities you enjoy most.
Downtown Houston
Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Top South Main Hotel Reviews
Cambria Hotel Houston Downtown Convention Center
10/10 Excellent
