Top 10 Hotels Near Museum of Life and Science in Raleigh for 2026

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Our top choices for Museum of Life and Science hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

1. Hampton Inn & Suites Durham/North I-85

1.4 km from Museum of Life and Science

Darrel

RM500

RM568 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A restaurant with a large ice dispenser, wooden paneling, and red cushioned booths.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a clear sky.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent entrance and a landscaped front yard.

2. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.2 km from Museum of Life and Science

BRIAN

RM378

RM430 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A gym with various exercise machines, a large mirror, and a television on the wall.

A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

3. Holiday Inn Express Durham by IHG

2.2 km from Museum of Life and Science

Kimberly R

RM433

RM491 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

A Red Roof Cafe with a stone wall, a coffee machine, and two white chairs.

A Red Roof Inn with a modern architectural design, featuring a prominent red sign and a well-maintained lawn.

4. Red Roof Inn Durham - Duke Univ Medical Center

2.2 km from Museum of Life and Science

Luis

RM256

RM298 total

includes taxes & fees

1 Nov - 2 Nov

5. Super 8 by Wyndham Durham/University Area NC

2.1 km from Museum of Life and Science

Jacqueline

RM317

RM358 total

includes taxes & fees

25 Oct - 26 Oct

A modern kitchen with a central island, wooden flooring, and large windows.

A kitchen counter with a coffee maker, a box of tissues, and a tray of snacks.

A spacious kitchen with a dining area, wooden flooring, and a modern design.

A dining area with a wooden table and benches, a chandelier, and a view into a living room with a sofa and a kitchen in the background.

6. Stylish Durham Retreat - Walkable, Sleeps 6

2.8 km from Museum of Life and Science

RM1,160

RM2,931 total

includes taxes & fees

8 Nov - 9 Nov

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

7. Hampton Inn & Suites Durham University Medical Center

4.8 km from Museum of Life and Science

Nicole

RM517

RM587 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A multi-story hotel with a brick facade, large windows, and a well-lit entrance.

A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

A hotel room with two beds, a desk, a chair, a sofa, and a TV.

8. Fairfield by Marriott Inn & Suites Durham

17.3 km from Museum of Life and Science

Chip

RM485

RM550 total

includes taxes & fees

25 Oct - 26 Oct

A modern lobby with a central seating area, a TV screen, and a patterned wall.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

A reception area with a counter, a welcome sign, a digital screen, and a hallway leading to a dining area.

A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.

9. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

17.5 km from Museum of Life and Science

Maurice

RM482

RM546 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

10. Hyatt House Raleigh / RDU / Brier Creek

17.1 km from Museum of Life and Science

Alton

RM449

RM509 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio with a stone fire pit, seating, and a covered area.

A reception area with a wooden counter, a 'HELLO Morrisville' sign, a 'PINCH' sign above a snack display, and a 'Manager on Duty' sign.

A modern dining area with wooden tables and chairs, a kitchen in the background, and a counter with stools.

A hotel room with a bed, a desk, and a chair. There is a door and a wall-mounted lamp.

11. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

19.7 km from Museum of Life and Science

Anthony

RM413

RM467 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with high ceilings, a central fountain, and seating areas.

An outdoor patio area with wicker furniture, stone pillars, and string lights.

A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.

A bar area with multiple liquor cabinets and hanging pendant lights.

12. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

17.5 km from Museum of Life and Science

Darren C.

RM650

RM736 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A multi-story hotel with a prominent "HOME 2" sign, a brick facade, and a well-lit entrance.

A modern indoor space with multiple seating areas, including tables and chairs, a television, and decorative shelves.

13. Home2 Suites by Hilton Durham University Medical Center

4.8 km from Museum of Life and Science

katey

RM569

RM646 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor seating area with a circular fire pit surrounded by wicker chairs and a table.

A multi-story hotel with a flat facade, large windows, and a clear sky.

A modern hotel lobby with a mix of seating areas, a bar, and a large wall-mounted TV.

A reception area with a large screen displaying a sea view, a bench, and a sign indicating the location as Marriott Bonvoy.

14. SpringHill Suites by Marriott Durham Chapel Hill

12 km from Museum of Life and Science

Logan

RM483

RM548 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor dining area with tables and chairs, large windows, and a view of greenery.

A modern restaurant with long communal tables, hanging pendant lights, and geometric patterned walls.

A modern living room with a pool table, a sofa, and a dining area.

15. The Westin Raleigh-Durham Airport

17.5 km from Museum of Life and Science

Dina

RM878

RM995 total

includes taxes & fees

18 Oct - 19 Oct

A reception area with two wooden reception desks, a potted plant, and a computer on the wall.

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

16. Courtyard Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

Sharon

RM565

RM640 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.

A modern living room with a fireplace, seating area, and a pool table.

A modern reception area with a marble counter, a wooden bench, and a unique chandelier.

17. JB Duke Hotel

5.6 km from Museum of Life and Science

samantha

RM813

RM923 total

includes taxes & fees

12 Oct - 13 Oct

A swimming pool with lounge chairs and a wooden fence.

A spacious lobby with a reception desk, seating area, and artwork on the walls.

A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

18. Hyatt Place Durham Southpoint

15.3 km from Museum of Life and Science

Jessica

RM552

RM626 total

includes taxes & fees

21 Oct - 22 Oct

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.

A bar area with a granite countertop, wooden chairs, and a large television screen.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

19. Hilton Garden Inn Durham/University Medical Center

9th Street District, 3.3 km from Museum of Life and Science

Michael

RM535

RM607 total

includes taxes & fees

9 Nov - 10 Nov

An outdoor seating area with wicker furniture and a stone fire pit.

A conference room with a long table, chairs, and a modern chandelier.

A hotel lobby with a sofa, chairs, a table, and a large window offering a view of the building.

A modern hotel lobby with seating areas, large windows, and a dining section.

20. Residence Inn Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

Janet

RM569

RM645 total

includes taxes & fees

18 Oct - 19 Oct

View all properties

Compare popular hotels close to Museum of Life and Science

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,005 reviews	View
Comfort Inn & Suites Durham near Duke University	8.6 Excellent 1,168 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,003 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,000 reviews	View
Super 8 by Wyndham Durham/University Area NC	5.0 344 reviews	View

Top Museum of Life and Science Hotel Reviews

Millennium Hotel Durham

10/10 Excellent

"Very nice stay!"

Unscripted Durham, Part of JDV by Hyatt

8/10 Good

"The place was awesome! I'm not going into details....I came home with some bed bug bites......🤔"

Comfort Inn & Suites Durham near Duke University

8/10 Good

"Clean, good price/cost ratio"

The Lodge at Duke Medical Center

10/10 Excellent

"Good stay. Clean room but could use extra parking"

21c Museum Hotel Durham

10/10 Excellent

"Stellar customer service!! Look elsewhere for food."

University Inn Durham next to Duke University Medical Center

10/10 Excellent

"Loved this hotel . Clean and perfect location"

The Durham Hotel

8/10 Good

"They properly was really nice and I really like the decor and amenities. We were disappointed, however to learn upon arrival that they rooftop restaurant was closed for a private function. We were excited in advance for our trip about having some social time there, only to find that it was closed."

Landing Apartments Durham

10/10 Excellent

"The apartment was just like the pictures! We would recommend this for anyone"

Other attractions near Museum of Life and Science

Brightleaf Square

9.6/10 (8 reviews)

You can do some window-shopping at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.

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Vietnam Veterans Living Memorial

You can find out about the history of Durham with a trip to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area.

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Northgate Mall

8.2/10 (60 reviews)

You can search for that perfect souvenir at Northgate Mall during your stay in Durham. Experience the lively festivals or attend a sporting event in this family-friendly area.

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Duke Homestead

Learn about the local history of Durham when you take a trip to Duke Homestead. Attend a sporting event or visit the stunning cathedral in this family-friendly area.

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Fullsteam Brewery

7.4/10 (3 reviews)

You can take time to visit Fullsteam Brewery during your travels to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area.

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Durham Convention Center

8.2/10 (118 reviews)

Learn about the events happening in Durham Convention Center during your trip to Durham. Discover the entertainment choices and stunning cathedral in this family-friendly area.

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African American Dance Ensemble

8.8/10 (3 reviews)

You can enjoy some culture when you stop by African American Dance Ensemble in Durham.

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Carolina Theatre

8.2/10 (220 reviews)

You can get tickets for a performance at Carolina Theatre during your stay in Durham. Experience the area's entertainment choices or attend a sporting event.

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Frequently asked questions

What's the area like around Museum of Life and Science?

Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, take a look at the 10 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near Museum of Life and Science?

Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find close to Museum of Life and Science?

Expedia has 10 hotels and other accommodation options within a mile from Museum of Life and Science.

If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Museum of Life and Science.

What can I see and do near Museum of Life and Science?

You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium and Wallace Wade Stadium. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Hotels near Museum of Life and Science

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Our top choices for Museum of Life and Science hotels

1. Hampton Inn & Suites Durham/North I-85

2. Comfort Inn & Suites Durham near Duke University

3. Holiday Inn Express Durham by IHG

4. Red Roof Inn Durham - Duke Univ Medical Center

5. Super 8 by Wyndham Durham/University Area NC

6. Stylish Durham Retreat - Walkable, Sleeps 6

7. Hampton Inn & Suites Durham University Medical Center

8. Fairfield by Marriott Inn & Suites Durham

9. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

10. Hyatt House Raleigh / RDU / Brier Creek

11. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

12. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

13. Home2 Suites by Hilton Durham University Medical Center

14. SpringHill Suites by Marriott Durham Chapel Hill

15. The Westin Raleigh-Durham Airport

16. Courtyard Raleigh-Durham Airport/Brier Creek

17. JB Duke Hotel

18. Hyatt Place Durham Southpoint

19. Hilton Garden Inn Durham/University Medical Center

20. Residence Inn Raleigh-Durham Airport/Brier Creek

Compare popular hotels close to Museum of Life and Science

Top Museum of Life and Science Hotel Reviews

Millennium Hotel Durham

Unscripted Durham, Part of JDV by Hyatt

Comfort Inn & Suites Durham near Duke University

The Lodge at Duke Medical Center

21c Museum Hotel Durham

University Inn Durham next to Duke University Medical Center

The Durham Hotel

Landing Apartments Durham

Other attractions near Museum of Life and Science

Brightleaf Square

Vietnam Veterans Living Memorial

Northgate Mall

Duke Homestead

Fullsteam Brewery

Durham Convention Center

African American Dance Ensemble

Carolina Theatre

Frequently asked questions