Travel to Southern Minnesota

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Where to stay in Southern Minnesota

Find the best Southern Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southern Minnesota
Rochester showing skyline and a city

Downtown Rochester

2 out of top 10 points of interest in this area

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Find hotels in Downtown Rochester

Top hotels in Southern Minnesota

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is RM332 per night from 21 Jul to 22 Jul
RM332
RM382 total
21 Jul - 22 Jul
includes taxes & fees
8/10 Very Good! (930 reviews)
Very pet friendly
"This hotel is excellent for pets we had a bottom floor room with a patio that leads to the pet area perfect for our dog to get to the bathroom easy"

Reviewed on 14 Jul 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
8.2/10 Very Good! (1,450 reviews)
"Always clean, always convenient"

Reviewed on 14 Jul 2025

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Kahler Grand Hotel
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is RM340 per night from 18 Jul to 19 Jul
RM340
RM391 total
18 Jul - 19 Jul
includes taxes & fees
7.8/10 Good! (1,001 reviews)
For Mayo visit
"Clean and cool enough bit would suggest a fan. Okay beakfast eats. Coffee is good."

Reviewed on 16 Jul 2025

Med City Inn & Suites - Mayo Clinic Area
See all 1,150 properties in Southern Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Apache Mall

During your visit to Rochester, you can find the perfect gifts to bring home at Apache Mall. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Apache Mall

Laura Ingalls Wilder Museum

You can spend time studying the exhibits at Laura Ingalls Wilder Museum in Walnut Grove. Take in the museums while you're in the area.

Laura Ingalls Wilder Museum

Frequently asked questions

How much does a Southern Minnesota holiday package cost?
Live it up in Southern Minnesota from as low as . We offer a great selection of rental cars, hotels and flights to suit every style and budget. You can pick up even better deals when you add some activities or tours to your holiday package.
How do I get a cheap travel package to Southern Minnesota?
Imagine all the amazing things you could do in Southern Minnesota with extra cash in your wallet. Watch your savings stack up when you bundle your flights, hotels and other bookings into a Southern Minnesota holiday package. You have loads of choice when you book with Expedia too. In fact, you can select from more than 550 airlines and 1,000,000 hotel options worldwide. Whether you're taking off with the entire family or travelling on your own, planning a getaway to Southern Minnesota is better with a package.
What are the top hotels in Southern Minnesota?
For properties in Rochester with cosy beds and friendly service, look up Kahler Inn and Suites - Mayo Clinic Area and Kahler Grand Hotel. If you're stopping by Lake City as well, you can look forward to a great night's sleep at Pet - Friendly Wabasha Studio: Boat or Peaceful Condo In Wabasha With Beautiful River Bluff Location - Lower Unit.
How far in advance should I book my Southern Minnesota holiday?
It can be hard to know when the best time is to book your holiday to Southern Minnesota. But typically the earlier you book, the more affordable the prices. In some cases, you can secure your flights and hotels up to a year before your departure date. If you're thinking of a last-minute getaway, no need to fret! There are great bargains popping up on Expedia all the time.
What does an Expedia Southern Minnesota travel package include?
Much of that depends on you. You can choose from a variety of Southern Minnesota bundles, such as a rental car, flight and hotel. You can also book a flight with a hotel, or a flight with a rental car. Once you've made your booking, you can add the fun stuff like activities and tours. Whatever your dream Southern Minnesota break looks like, you're sure to save!
What should I know before booking a Southern Minnesota travel package?
Bundling your bookings into a Southern Minnesota holiday package is the most convenient way to organise your trip. Not only that, you'll get great discounts when you combine your hotels, flights and car rentals. Once you've booked, why not add on an activity or a tour?
Can I choose my airline with a Southern Minnesota Expedia holiday package?
Yes, you sure can. We offer more than 550 airline partners all over the world, so fly with the carrier that best fits your budget and travel needs.
If I'm not able to travel, can I cancel my Southern Minnesota holiday package?
We totally get it --- life sometimes gets in the way of your plans. If you've booked a Southern Minnesota holiday package and have to cancel or change it, we can help. We suggest browsing our Customer Service Portal first for information. But generally, if you've booked your package in the last 24 hours, you may be able to cancel or amend your itinerary at no cost. If it's been longer than 24 hours, your airline, hotel or car rental company may impose a fee.