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Upstate South Carolina hotels from RM262
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very good, (710 reviews)
The price is RM341
RM400 total
includes taxes & fees
10 Jun - 11 Jun

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (623 reviews)
The price is RM443
RM492 total
includes taxes & fees
14 Jun - 15 Jun

Hampton Inn Anderson/ Alliance Business Park
Hampton Inn Anderson/ Alliance Business ParkAnderson
9.2 out of 10, Wonderful, (846 reviews)
The price is RM457
RM508 total
includes taxes & fees
14 Jun - 15 Jun

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (462 reviews)
The price is RM560
RM611 total
includes taxes & fees
14 Jun - 15 Jun

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (234 reviews)
The price is RM521
RM573 total
includes taxes & fees
11 Jun - 12 Jun

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,008 reviews)
The price is RM439
RM545 total
includes taxes & fees
9 Jun - 10 Jun

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (858 reviews)
The price is RM600
RM667 total
includes taxes & fees
9 Jun - 10 Jun

Days Inn by Wyndham Greenville South/Mauldin
Days Inn by Wyndham Greenville South/MauldinMauldin
7.6 out of 10, Good, (706 reviews)
The price is RM291
RM320 total
includes taxes & fees
21 Jun - 22 Jun

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (741 reviews)
The price is RM442
RM491 total
includes taxes & fees
2 Jul - 3 Jul

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very good, (1,004 reviews)
The price is RM384
RM426 total
includes taxes & fees
10 Jun - 11 Jun

Quality Inn Clinton - Laurens I-26
Quality Inn Clinton - Laurens I-26Clinton
7.4 out of 10, Good, (554 reviews)
The price is RM255
RM299 total
includes taxes & fees
3 Jul - 4 Jul

Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/ClemsonAnderson
8.4 out of 10, Very good, (1,004 reviews)
The price is RM322
RM357 total
includes taxes & fees
5 Jul - 6 Jul

Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (742 reviews)
The price is RM499
RM559 total
includes taxes & fees
3 Jul - 4 Jul

Deluxe Inn
Deluxe InnMauldin
9.6 out of 10, Exceptional, (4 reviews)
The price is RM254
RM279 total
includes taxes & fees
8 Jun - 9 Jun

Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (499 reviews)
The price is RM339
RM369 total
includes taxes & fees
5 Jul - 6 Jul

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,251 reviews)
The price is RM501
RM551 total
includes taxes & fees
14 Jun - 15 Jun

Courtyard by Marriott Greenville Mauldin
Courtyard by Marriott Greenville MauldinGreenville
9.2 out of 10, Wonderful, (352 reviews)
The price is RM480
RM528 total
includes taxes & fees
14 Jun - 15 Jun

Best Western Spartanburg Northwest
Best Western Spartanburg NorthwestSpartanburg
8.4 out of 10, Very good, (916 reviews)
The price is RM335
RM372 total
includes taxes & fees
15 Jun - 16 Jun

The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown ClemsonClemson
9.8 out of 10, Exceptional, (811 reviews)
The price is RM613
RM680 total
includes taxes & fees
9 Jun - 10 Jun

Best Western Plus Spartanburg
Best Western Plus SpartanburgSpartanburg
8.4 out of 10, Very good, (1,003 reviews)
The price is RM351
RM398 total
includes taxes & fees
28 Jun - 29 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (76 reviews)
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Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center
10/10 Excellent
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is RM236 per night from 6 Jul to 7 Jul
RM236
RM262 total
6 Jul - 7 Jul
includes taxes & fees
6/10 (611 reviews)

4 Star Hotels
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- Barnet Park
- Cedar Lane Shopping Center
- Centre West Shopping Center
- Conestee Nature Preserve
- Frankie's Fun Park
- Golden Lanes and Golden Skate
- Visit Gramling
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- Greenville Holidays
- Hatcher Garden and Woodland Preserve
- Heritage Green
- Hollywild Animal Park
- Inman Holidays
- Visit Landrum
- Logos Theatre
- North Grove Medical Park
- Visit Pauline
- Visit Startex
- Topgolf Greenville
- Wade Hampton Plaza Shopping Center
- Visit Wellford
- Younts Center for Performing Arts










































































































































