A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

Hotels near St. Louis Science Center

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
7 Aug - 9 Aug
In two weeks
14 Aug - 16 Aug

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for St. Louis Science Center hotels

Indoor pool

1. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 1 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"The staff was very hospitable and tending to my family’s needs we enjoyed our stay thanks to the Hampton Inn’s staff 😊"
United States
Orleanna
The price is RM566
RM668 total
includes taxes & fees
9 Aug - 10 Aug
Hampton Inn & Suites St. Louis at Forest Park
Exterior

2. Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
2 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"We loved the free dinner and breakfast! Perfect for traveling with kids!"
United States
Sabrina
The price is RM609
RM712 total
includes taxes & fees
9 Aug - 10 Aug
Drury Inn & Suites St. Louis Forest Park
Courtyard

3. Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown
3.0 star property
Midtown, 2.7 km from St. Louis Science Center
9.0 out of 10, Wonderful, (795 reviews)
"Really enjoyed my stay I will return"
United States
Brittany
The price is RM552
RM645 total
includes taxes & fees
9 Aug - 10 Aug
Element by Marriott St. Louis Midtown
Lobby

4. AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End, 1.8 km from St. Louis Science Center
9.0 out of 10, Wonderful, (802 reviews)
"Great location."
United States
Blake
The price is RM584
RM689 total
includes taxes & fees
9 Aug - 10 Aug
AC Hotel St. Louis Central West End
Seasonal outdoor pool

5. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 1.8 km from St. Louis Science Center
9.0 out of 10, Wonderful, (1,002 reviews)
"Enjoyed our stay!"
United States
Patricia
The price is RM752
RM1,007 total
includes taxes & fees
16 Aug - 17 Aug
The Royal Sonesta Chase Park Plaza St. Louis
Restaurant

6. Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 1.7 km from St. Louis Science Center
8.8 out of 10, Excellent, (1,006 reviews)
"Great stay!"
United States
Morgan
The price is RM531
RM671 total
includes taxes & fees
30 Aug - 31 Aug
Hotel Indigo St Louis - Central West End by IHG
Bar (on property)

7. Aloft by Marriott St. Louis Cortex

Aloft by Marriott St. Louis Cortex
3.0 star property
Central West End, 1.8 km from St. Louis Science Center
8.6 out of 10, Excellent, (994 reviews)
"Very nice hotel staff were great water was hot the entire stay clean rooms"
United States
Khristina
The price is RM465
RM544 total
includes taxes & fees
4 Aug - 5 Aug
Aloft by Marriott St. Louis Cortex
Outdoor spa tub

8. The West End

The West End
2.0 star property
Central West End, 2.3 km from St. Louis Science Center
8.6 out of 10, Excellent, (592 reviews)
"Good and comfortable place to stay"
United States
Isabella
The price is RM366
RM509 total
includes taxes & fees
3 Aug - 4 Aug
The West End
Terrace/patio

9. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 0.9 km from St. Louis Science Center
8.6 out of 10, Excellent, (1,002 reviews)
"Staff was nice and helpful food was great and room was amazing!!! "
United States
paullita jeanne
The price is RM680
RM680 total
includes taxes & fees
16 Aug - 17 Aug
Home2 Suites by Hilton St. Louis/Forest Park
In-room safe, desk, blackout curtains, iron/ironing board

10. DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End, 1.3 km from St. Louis Science Center
8.4 out of 10, Very good, (1,002 reviews)
"Beautiful hotel in a convenient locations. Walking distance to great restaurants and coffee shops."
United States
Gary
The price is RM566
RM668 total
includes taxes & fees
9 Aug - 10 Aug
DoubleTree by Hilton St. Louis Forest Park
Lobby

11. White House at Grand Central

White House at Grand Central
3.5 star property
3 km from St. Louis Science Center
8.4 out of 10, Very good, (151 reviews)
"Staff was great and accommodating to my needs."
United States
Triman
The price is RM329
RM528 total
includes taxes & fees
3 Aug - 4 Aug
White House at Grand Central
Premium bedding, iron/ironing board (on request), free WiFi, bed sheets

12. Central West End B&B

Central West End B&B
3.5 star property
Central West End, 3 km from St. Louis Science Center
8.0 out of 10, Very good, (56 reviews)
"Really enjoyed the comfort. I would recommend this place to anyone. Very nice breakfast also!!! "
United States
Stacee
The price is RM673
RM846 total
includes taxes & fees
5 Aug - 6 Aug
Central West End B&B
Premium bedding, pillow-top beds, desk, laptop workspace

13. Forest Park Hotel by MDR

Forest Park Hotel by MDR
3.0 star property
The Hill, 1.8 km from St. Louis Science Center
7.4 out of 10, Good, (1,640 reviews)
"Nice affordable room, great staff"
United States
Eviticus
The price is RM335
RM411 total
includes taxes & fees
31 Aug - 1 Sept
Forest Park Hotel by MDR
In-room safe, desk, blackout curtains, iron/ironing board (on request)

14. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
2.5 star property
The Hill, 1.8 km from St. Louis Science Center
6.0 out of 10, (1,005 reviews)
"Clean room , no bugs … nice staff, good coffee, and lots of food choices near"
United States
Mary
The price is RM345
RM404 total
includes taxes & fees
1 Sept - 2 Sept
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
Lobby lounge

15. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
6.5 km from St. Louis Science Center
9.6 out of 10, Exceptional, (1,002 reviews)
"Would definitely stay again!!"
United States
cassandra
The price is RM556
RM660 total
includes taxes & fees
9 Aug - 10 Aug
Drury Plaza Hotel St. Louis Brentwood
Hallway

16. Benton Park Inn

Benton Park Inn
3.5 star property
5.5 km from St. Louis Science Center
9.6 out of 10, Exceptional, (339 reviews)
"The host was super friendly, and the house was really cute. We loved the quiet neighborhood, and the breakfast the host prepared was great! We would absolutely stay again!"
United States
Shane
The price is RM609
RM712 total
includes taxes & fees
4 Aug - 5 Aug
Benton Park Inn
Miscellaneous

17. The Lodge at Grant's Trail

The Lodge at Grant's Trail
3.5 star property
10.1 km from St. Louis Science Center
9.6 out of 10, Exceptional, (521 reviews)
"Everything about it was great. My girlfriend and I loved it."
United States
Tracy
The price is RM609
RM700 total
includes taxes & fees
3 Aug - 4 Aug
The Lodge at Grant's Trail
Interior

18. Truitt Hotel

Truitt Hotel
2.0 star property
Lafayette Square, 4.9 km from St. Louis Science Center
The price is RM768
RM929 total
includes taxes & fees
3 Aug - 4 Aug
Truitt Hotel
Terrace/patio

19. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
5.5 km from St. Louis Science Center
9.4 out of 10, Exceptional, (898 reviews)
"Clean room, comfy bed, friendly staff, great location!! Would definitely stay here again!!"
United States
MARY
The price is RM413
RM507 total
includes taxes & fees
16 Aug - 17 Aug
Courtyard by Marriott St. Louis Brentwood
Breakfast, lunch and dinner served

20. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 6.7 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,273 reviews)
"Perfect location, clean and comfortable beds!"
United States
Cindy
The price is RM650
RM773 total
includes taxes & fees
6 Aug - 7 Aug
Live by Loews - St.Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to St. Louis Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Indoor pool
Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
9.4
Exceptional
1,004 reviews
View
Exterior
Drury Inn & Suites St. Louis Forest Park
3.0 star property
9.4
Exceptional
1,004 reviews
View
Courtyard
Element by Marriott St. Louis Midtown
3.0 star property
9.0
Wonderful
795 reviews
View
Lobby
AC Hotel St. Louis Central West End
4.0 star property
9.0
Wonderful
802 reviews
View
Seasonal outdoor pool
The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
9.0
Wonderful
1,002 reviews
View

Top St. Louis Science Center Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good
"The elevators were broken and there was a pail to catch leaking water nearby them . Breakfast was fine but I find the need to be seated by a server for a buffet ,( yet you’re getting your own drinks and food )is just a bit bizarre . Tip: get a freshly prepared omelet , because other wise there is no cheese or fresh veggies offered at the buffet . Overall I think it’s a safe area to stay and it wasn’t awful. Beds not too comfy and room is a bit dated . (Remote wouldn’t work ) . I called the front desk to see if they could switch out the remote. They said they would send someone up but they never came . It’s tough to have a tv on and you can’t change the channel . Pointless . Popcorn ceilings . Expensive vending machine and no complimentary water /water bottle ."
Ashley 2-night trip
Posted 4 hours ago
Clayton Plaza Hotel & Extended Stay

Other attractions near St. Louis Science Center

A modern building with large glass windows and a garden with red and pink tulips.

Jewel Box

Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain.
See properties

Frequently asked questions

What's the area like around St. Louis Science Center?
St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, take a look at the 65 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near St. Louis Science Center?
Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good choices within a short distance include DoubleTree by Hilton St. Louis Forest Park and Home2 Suites by Hilton St. Louis/Forest Park.
How many hotels should I expect to find close to St. Louis Science Center?
Expedia has 65 hotels and other accommodation options within a mile from St. Louis Science Center.
If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals near St. Louis Science Center.
What can I see and do near St. Louis Science Center?
Cathedral Basilica of St. Louis, St. Louis Art Museum and City Museum feature captivating exhibits. St. Louis Union Station, Jewel Box and Cherokee Street are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater and Sheldon Concert Hall.