Santa Ana
Panama City
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Amador Causeway
You can learn about the history of Ancon with a visit to Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
Cinta Costera
After visiting Cinta Costera, make a plan to see the other sights and activities in Panama City. While you're in the area, stroll along the seaside.
Calle 50
You can find out about the history of Panama City when you stop by Calle 50. Discover the area's casinos or seek out its local tours.
Uruguay Street
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
Things to do
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City: Zip Line Experience Over The City
Panama City: POIN Swing Experience
Panama Canal:Monkey Island,Sloth Safari, Natural Pool & Hike
Top hotels in Santa Ana
Casco View Apartments
Nice place, easy walk from Casco Viejo. The pool area was great, but room wasn’t the cleanest. We had to request bedding for the second bed but weren’t given a blanket.
Reviewed on 7 Apr 2026
Hotel Riu Plaza Panama
We stayed for 7 nights. The hotel is in a safe neighborhood and within walking distance to so many restaurants - I think the farthest we had to walk was 7 minutes to a restaurant. We stayed in a king bed room and the room was very spacious - there was a small fridge and iron with ironing board and ...
Reviewed on 10 Apr 2026
Crowne Plaza Panama Airport by IHG
Only there for one night but had everything we needed.
Reviewed on 10 Apr 2026
Sheraton Grand Panama
The staff greeted us with a warm smile every day. The breakfast was delicious. We would definitely stay here again.
Reviewed on 10 Apr 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
When we initially checked in to the property we were given a room on the first floor. Upon arrival the door did n
Reviewed on 11 Apr 2026
Principe Hotel and Suites
Ok
Reviewed on 11 Apr 2026
Other neighbourhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.
El Chorrillo
While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Flag of Cerro Ancón are some notable places to visit nearby.
Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.
Balboa
The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Flag of Cerro Ancón are a few top places to visit.
Curundu
While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.
