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Hotels in Santa Ana, Panama City

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18 Nov - 19 Nov
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21 Nov - 23 Nov
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Top 10 Hotels in Santa Ana, Panama City

Balcony
Casco View Apartments

Casco View Apartments

3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (50)
"Great stay, would recommend."
United States
Brooke
Casco View Apartments
Balcony
Hotel República

Hotel República

2.0 star property
Santa Ana
6.6 out of 10, (180)
"Fantastic customer service"
United States
OLGA
Hotel República
Bar (on property)
Hostal La Cigarra

Hostal La Cigarra

2.0 star property
Santa Ana
7.6 out of 10, Good, (54)
"Helpful staff, secure, close to sights"
Australia
Suzanne
The price is RM105
RM116 total
includes taxes & fees
22 Nov - 23 Nov
Hostal La Cigarra
Front of property
ART CASCO The Hotel

ART CASCO The Hotel

2.0 star property
Santa Ana
5.8 out of 10, (10)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
ART CASCO The Hotel
1 bedroom, iron/ironing board, free WiFi, bed sheets
La Manzana by Wynwood House

La Manzana by Wynwood House

3.0 star property
Santa Ana
7.2 out of 10, Good, (15)
"Great hotel. Very close to Casco viejo"
United States
LUCILA
The price is RM201
RM304 total
includes taxes & fees
24 Nov - 25 Nov
La Manzana by Wynwood House
Pool
Room-sofa Bed Stay Rooftop Pool & Gym, A

Room-sofa Bed Stay Rooftop Pool & Gym, A

2.0 star property
Santa Ana
2.0 out of 10, (1)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is RM609
RM670 total
includes taxes & fees
2 Dec - 3 Dec
Room-sofa Bed Stay Rooftop Pool & Gym, A
Terrace/patio
Casa Quijano 06 By Wynwood House

Casa Quijano 06 By Wynwood House

4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (4)
"Easy to find, seamless check-in "
Canada
Matthew
Casa Quijano 06 By Wynwood House
Outdoor pool, pool umbrellas, pool loungers
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4.0 star property
21.1 km from Santa Ana
8.4 out of 10, Very good, (2272)
"Spacious room, clean, good breakfast "
United States
Juan
The price is RM457
RM503 total
includes taxes & fees
26 Nov - 27 Nov
Crowne Plaza Panama Airport by IHG
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4.0 star property
San Felipe, 0.9 km from Santa Ana
9.0 out of 10, Wonderful, (1002)
"Hotel was beautiful, staff was very helpful and accommodating. We had the pool two separate days to ourselves. Breakfadt was very good. Staff was very helpful getting us drivers wherever we wanted to go in the city."
United States
MICHELE
Central Hotel Panama Casco Viejo
Reception
Hotel Coral Suites

Hotel Coral Suites

3.5 star property
El Cangrejo, 3.7 km from Santa Ana
9.0 out of 10, Wonderful, (1002)
"Great place for the price. "
United States
Ryan
The price is RM288
RM317 total
includes taxes & fees
21 Nov - 22 Nov
Hotel Coral Suites
Front of property
La Concordia Boutique Hotel

La Concordia Boutique Hotel

4.0 star property
San Felipe, 0.5 km from Santa Ana
9.6 out of 10, Exceptional, (192)
"The staff was very friendly and supportive. The room was spectacular! It was beautifully decorated and very clean. It was just a delight to stay in this lovely hotel!"
United States
Madelaine
The price is RM1,027
RM1,130 total
includes taxes & fees
18 Dec - 19 Dec
La Concordia Boutique Hotel
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

5.0 star property
Bella Vista, 2.9 km from Santa Ana
9.0 out of 10, Wonderful, (1003)
"Very beautiful room was spotless, and staff was very good with customer service"
United States
Anthony
The price is RM712
RM783 total
includes taxes & fees
1 Dec - 2 Dec
Waldorf Astoria Panama
Front of property – evening/night
Principe Hotel and Suites

Principe Hotel and Suites

3.0 star property
El Cangrejo, 3.9 km from Santa Ana
9.0 out of 10, Wonderful, (1553)
"Clean from affordable pleasant staff was very nice stay "
United States
Iris
The price is RM212
RM233 total
includes taxes & fees
23 Nov - 24 Nov
Principe Hotel and Suites
Front of property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 star property
Punta Paitilla, 3.5 km from Santa Ana
8.4 out of 10, Very good, (1212)
"Great stay "
United States
Mark
Megapolis Hotel Panamá
Outdoor pool, pool loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (4537)
"Great place to stay "
United States
yohosy
The price is RM493
RM542 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Riu Plaza Panama
Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

3.5 star property
Obarrio, 3.6 km from Santa Ana
7.6 out of 10, Good, (675)
"The breakfast was great, I love the pool."
United States
Estefani
The price is RM230
RM253 total
includes taxes & fees
20 Nov - 21 Nov
Hospedium Princess Hotel Panama
Outdoor spa tub
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

3.5 star property
El Cangrejo, 3.5 km from Santa Ana
9.2 out of 10, Wonderful, (1008)
"Staff was helpful, room was clean and I enjoyed my stay. "
United States
Lystra
The price is RM320
RM352 total
includes taxes & fees
2 Dec - 3 Dec
TRYP by Wyndham Panamá Centro
View from property
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2132)
"Very nice hotel, all amenities met our needs. "
Canada
gordon
The price is RM426
RM469 total
includes taxes & fees
2 Dec - 3 Dec
Plaza Paitilla Inn Hotel
Front of property
Novotel Panama City

Novotel Panama City

4.0 star property
El Cangrejo, 4.3 km from Santa Ana
9.2 out of 10, Wonderful, (1004)
"Room very clean, nice staffs and good location "
United States
Hayden
The price is RM378
RM415 total
includes taxes & fees
9 Dec - 10 Dec
Novotel Panama City
Premium bedding, minibar, in-room safe, desk
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (629)
"Beautiful property. Excellent lunch, fish tacos were amazing. "
United States
Marc
The price is RM869
RM956 total
includes taxes & fees
23 Nov - 24 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

While visiting San Felipe, you might make a stop by sights like Interoceanic Canal Museum and National Theater.

Top Santa Ana Hotel Reviews

Megapolis Hotel Panamá

Megapolis Hotel Panamá

10/10 Excellent
"Clean room, the best part was the view from the room"
Mary 4-night trip
Posted 3 days ago
Megapolis Hotel Panamá

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Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Cinta Costera and Avenida Balboa while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.
How many hotels can I expect to find in Santa Ana?
Expedia has 96 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighbourhood. Albrook Shopping Mall, Amador Theater and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.