Santa Ana

Panama City

Plaza Santa Ana, Panama Casco Viejo
Plaza Santa Ana, Panama Casco Viejo
View from the fish market
go there and eat fresh and yummy fish in all variations

Popular places to visit

Things to do


Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
Stay at this condo in Panama City. Enjoy free Wi-Fi, a 24-hour front desk and a garden. Popular attractions Albrook Shopping Mall and Cinta Costera are located ...
9/10 Wonderful! (74 reviews)
The room was spotless and the decor was beautiful. The location was very convenient and the staff was friendly, in particular Marciello. The only downsides were that there was no hot water in the shower and the air conditioning vented onto the deck, making it really hot to sit on the deck.

Reviewed on 22 Feb 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is RM470 per night from 8 Mar to 9 Mar
RM470
RM516 total
8 Mar - 9 Mar
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,030 reviews)
3rd time there. Love it

Reviewed on 24 Feb 2026

Hotel Riu Plaza Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
The price is RM420 per night from 26 Feb to 27 Feb
RM420
RM462 total
26 Feb - 27 Feb
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
7.8/10 Good! (1,025 reviews)
Room was clean, staff was friendly, well maintained property

Reviewed on 24 Feb 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is RM464 per night from 5 Mar to 6 Mar
RM464
RM510 total
5 Mar - 6 Mar
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,455 reviews)
Room was great but the shuttle didn’t show up at T2 for 12:25, so I had to take a taxi. Then when I mentioned it to the front desk staff that it never arrived he first ignored me and was very rude, and then when I asked him to mention it to management he gaslit me and said it did arrive and that ...

Reviewed on 24 Feb 2026

Crowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is RM522 per night from 8 Mar to 9 Mar
RM522
RM574 total
8 Mar - 9 Mar
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,000 reviews)
The staff was courteous and overall very helpful. The spaces were clean. They had easy access to taxis if you needed them and the breakfast buffet, and restaurants were delicious. We did ask for extra water a few times and it was stated it would be brought up and never was. Other than that, the stay ...

Reviewed on 23 Feb 2026

Sheraton Grand Panama
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
The price is RM775 per night from 9 Mar to 10 Mar
RM775
RM852 total
9 Mar - 10 Mar
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs and 2 bars/lounges. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (1,000 reviews)
This place never disappoints! This is our second stay here in the last 30 days! Staff is impeccable they helped to make our anniversary and my husbands birthday special! The rooms are gorgeous and the room service and breakfast buffet are both top notch! You couldn’t be in a better area close to ...

Reviewed on 24 Feb 2026

W Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

View of the Panama City Old Town

Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

San Felipe
Default Image

El Chorrillo

While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Maracana Stadium are some notable places to visit nearby.

El Chorrillo
The skyline at Panama City, Panama. There are some nice walkways along the waterfront.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Calidonia
The buses of Panama.

Balboa

The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Bridge of the Americas are a few top places to visit.

Balboa
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


Santa Ana