Santa Ana

Panama City

Photo by Isa
Photo by Isa

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

4.5/5(8 reviews)

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

4/5(5 reviews)

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Avenida Balboa

Avenida Balboa

3.5/5(9 reviews)

You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Fuerte Amador Resort & Marina

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Visit the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina
Panama

Miraflores Locks

4.5/5(12 reviews)

Learn about the local history of Ancon when you spend time at Miraflores Locks. Visit the shops and casinos in this vibrant area.

Miraflores Locks
Calle 50

Calle 50

You can find out about the history of Panama City when you stop by Calle 50. Discover the area's casinos or seek out its local tours.

Calle 50

Things to do

Panama City: All-Inclusive Catamaran Cruise to Taboga Island

Panama City: All-Inclusive Catamaran Cruise to Taboga Island

RM416
per adult
94% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

RM193
per adult
96% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City: Zip Line Experience Over The City & a Cocktail

Panama City: Zip Line Experience Over The City

RM168
per adult
90% of travellers recommend
Panama City: Zip Line Experience Over The City
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

RM416
per adult
94% of travellers recommend
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Bridge of the Americas

Private or Small Group Panama Canal & City Half-Day Tour

RM281
per adult
100% of travellers recommend
Private or Small Group Panama Canal & City Half-Day Tour
Boat tour in the Panama Canal to Monkeys and sloths islands

Boat tour in the Panama Canal to Monkeys and sloths islands

RM311
per adult
92% of travellers recommend
Boat tour in the Panama Canal to Monkeys and sloths islands
See all activities in Panama City

Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste, Panama City, Provincia de Panamá
Stay at this 3.5-star condo in Panama City. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions Albrook Shopping Mall and Cinta Costera ...
9.2/10 Wonderful! (48 reviews)
"Great stay, would recommend."

Reviewed on 4 Sept 2025

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Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is RM499 per night from 6 Oct to 7 Oct
RM499
RM549 total
6 Oct - 7 Oct
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,353 reviews)
"Verry good i drove to albrook mall"

Reviewed on 28 Sept 2025

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is RM496 per night from 1 Nov to 2 Nov
RM496
RM546 total
1 Nov - 2 Nov
includes taxes & fees
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (2,253 reviews)
"Airport Shuttle was a neat addition to the reservation, very convenient and hassle free transportation to and from the airport."

Reviewed on 27 Sept 2025

Crowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
The price is RM564 per night from 13 Oct to 14 Oct
RM564
RM621 total
13 Oct - 14 Oct
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (954 reviews)
"Enjoyed my stay. Especially loved the gym. I will be back."

Reviewed on 27 Sept 2025

Sheraton Grand Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
The price is RM1,144 per night from 29 Oct to 30 Oct
RM1,144
RM1,144 total
29 Oct - 30 Oct
includes taxes & fees
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.4/10 Good! (1,007 reviews)
"Love this resort, spent my birthday here with a group of friends! was able to ungraded my room for only $80!!"

Reviewed on 26 Sept 2025

Dreams Playa Bonita Panama - All Inclusive
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
The price is RM353 per night from 29 Oct to 30 Oct
RM353
RM389 total
29 Oct - 30 Oct
includes taxes & fees
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
9/10 Wonderful! (506 reviews)
"This was my second stay, and I truly love this hotel! It’s very clean, the staff is always friendly, and the location near the train station is so convenient. Great value for the price—I’ll definitely return."

Reviewed on 27 Sept 2025

Waymore Hotel Spa & Casino
See all 1,561 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

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Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Casco Viejo
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San Felipe

While visiting San Felipe, you might make a stop by sights like Interoceanic Canal Museum and National Theater.

San Felipe
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El Chorrillo

While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Ancon Hill are some notable places to visit nearby.

El Chorrillo
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Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Calidonia
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Balboa

The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Bridge of the Americas are a few top places to visit.

Balboa
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Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella

Santa Ana