Visit Otay Mesa West
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's acclaimed art galleries and entertainment choices.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Balboa Park
One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Things to do
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Whale Watching & Dolphin Cruise
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
Maritime Museum of San Diego Admission Ticket
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
Top hotels in Otay Mesa West
Sheraton San Diego Resort
Great room. Very clean
Reviewed on 28 Dec 2025
Bay Club Hotel & Marina
Staff are very friendly. Daily room service is great! Marina view from room and lobby are amazing.only thing is facility is a bit old, especially bathroom tub and toilet are outdated. And it has a bit smell of mold in bathroom
Reviewed on 27 Dec 2025
The DEXTRO Little Italy, BW Premier Collection
Room was very clean Staff was great. Just be aware the hotel doesnt accept any cash at all.
Reviewed on 30 Dec 2025
Courtyard by Marriott San Diego Downtown Little Italy
Excellent
Reviewed on 27 Dec 2025
Legacy Resort Hotel & Spa
The rooms were spotless and quiet! We had a beautiful view from our balcony. Kassie was a wonderful hostess when we arrived to the end when we checked out. We will definitely be staying here again in the future. Thank you Kassie you were so kind and generous to our family. You are a great young ...
Reviewed on 27 Dec 2025
DoubleTree by Hilton Hotel San Diego - Mission Valley
Amenities were fantastic, nice staff, room carpet could be a lot cleaner
Reviewed on 29 Dec 2025
Other neighbourhoods around Otay Mesa West
East Village
Travellers choose East Village for its great bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Marina District
Known for its fantastic nightlife and captivating waterfront views, there's plenty to explore in Marina District. Check out top attractions like Seaport Village and The Rady Shell at Jacobs Park, and jump on the metro at Seaport Village Station or Convention Center Station to see more of the city.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
