Hotels in Otay Mesa West, San Diego

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Top 10 Hotels in Otay Mesa West, San Diego

Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
10.5 km from Otay Mesa West
9.2 out of 10, Wonderful, (3401)
"Clean, staff friendly, great place for a stay"
United States
Derrick
The price is RM480
RM529 total
includes taxes & fees
23 Nov - 24 Nov
Best Western Plus Marina Gateway Hotel
Lobby
El Cordova Hotel on Coronado Island

El Cordova Hotel on Coronado Island

3.5 star property
16.4 km from Otay Mesa West
8.8 out of 10, Excellent, (1004)
"Thank you - great spot! I will stay again ⭐️ "
United States
Donna
The price is RM578
RM761 total
includes taxes & fees
30 Nov - 1 Dec
El Cordova Hotel on Coronado Island
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
17.8 km from Otay Mesa West
9.0 out of 10, Wonderful, (2656)
"Very nice location and rooms. "
United States
David
The Horton Grand, Downtown/Gaslamp Quarter
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 17.6 km from Otay Mesa West
9.0 out of 10, Wonderful, (1208)
"Clean room ,friendly staff, great location "
United States
Jessica
The price is RM558
RM647 total
includes taxes & fees
19 Nov - 20 Nov
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Rooftop terrace
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 18.1 km from Otay Mesa West
8.6 out of 10, Excellent, (2031)
"Clean room, excellent staff and pleasant atmosphere "
United States
Estela
The price is RM475
RM551 total
includes taxes & fees
23 Nov - 24 Nov
Palihotel San Diego Gaslamp Quarter
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
19.2 km from Otay Mesa West
8.4 out of 10, Very good, (6043)
"I enjoyed my stay."
United States
Kevin
The price is RM558
RM767 total
includes taxes & fees
23 Nov - 24 Nov
Wyndham San Diego Bayside
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 17.5 km from Otay Mesa West
9.0 out of 10, Wonderful, (3077)
"Our stay was great! Would stay here again"
United States
Carla
The price is RM664
RM960 total
includes taxes & fees
8 Dec - 9 Dec
Hard Rock Hotel San Diego
Outdoor pool, pool loungers
Best Western Plus Suites Hotel Coronado Island

Best Western Plus Suites Hotel Coronado Island

2.5 star property
17.3 km from Otay Mesa West
8.8 out of 10, Excellent, (1003)
"Great staff and breakfast "
United States
Samantha
The price is RM631
RM694 total
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Suites Hotel Coronado Island
Exterior
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 18 km from Otay Mesa West
8.8 out of 10, Excellent, (950)
"Great spot in Gaslamp! "
United States
Cassie
The price is RM529
RM613 total
includes taxes & fees
14 Dec - 15 Dec
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
Lobby
Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego

2.5 star property
23.2 km from Otay Mesa West
8.2 out of 10, Very good, (1005)
"Great place "
United States
Fadi
The price is RM393
RM433 total
includes taxes & fees
11 Dec - 12 Dec
Best Western Plus La Mesa San Diego
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 18.2 km from Otay Mesa West
8.8 out of 10, Excellent, (1005)
"Nice and comfortable room"
United States
Jim
The price is RM459
RM522 total
includes taxes & fees
9 Dec - 10 Dec
Gaslamp Plaza Suites
Property entrance
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 star property
18.5 km from Otay Mesa West
8.6 out of 10, Excellent, (1428)
"Nice staff, comfortable beds"
United States
Amber
The Bristol Hotel San Diego
Front of property
The Sofia Hotel

The Sofia Hotel

3.5 star property
18.5 km from Otay Mesa West
8.4 out of 10, Very good, (1629)
"Excellent stay all-around!"
United States
Nalani
The Sofia Hotel
Pillow-top beds, in-room safe, desk, blackout curtains
Holiday Inn Express San Diego Downtown by IHG

Holiday Inn Express San Diego Downtown by IHG

2.5 star property
18.6 km from Otay Mesa West
8.4 out of 10, Very good, (1528)
"Very nice hotel. "
United States
James
The price is RM426
RM493 total
includes taxes & fees
15 Dec - 16 Dec
Holiday Inn Express San Diego Downtown by IHG
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 17.8 km from Otay Mesa West
9.4 out of 10, Exceptional, (1003)
"The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. "
United States
Samantha Erin
The price is RM443
RM633 total
includes taxes & fees
24 Nov - 25 Nov
Staypineapple, Hotel Z, Gaslamp San Diego
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

3.0 star property
North Pacific Beach, 29.8 km from Otay Mesa West
8.0 out of 10, Very good, (1403)
"Great place We will stay here again. "
United States
Derek
The price is RM422
RM485 total
includes taxes & fees
23 Nov - 24 Nov
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 star property
22.1 km from Otay Mesa West
9.0 out of 10, Wonderful, (3102)
"Great staff and beautiful location. "
United States
elaine
The price is RM461
RM530 total
includes taxes & fees
24 Nov - 25 Nov
Bay Club Hotel & Marina
Check-in/check-out kiosk
Urban Boutique Hotel

Urban Boutique Hotel

3.0 star property
Little Italy, 19.3 km from Otay Mesa West
8.6 out of 10, Excellent, (1277)
"Alwsys clean , great staff andvperfect location"
United States
Colleen
Urban Boutique Hotel
Exterior
La Pensione Hotel

La Pensione Hotel

3.0 star property
Little Italy, 19.4 km from Otay Mesa West
8.6 out of 10, Excellent, (1894)
"Friendly staff, very nice room, great location!"
United States
Lisa
La Pensione Hotel
Outdoor pool, pool umbrellas, pool loungers
Lamplighter Inn & Suites at SDSU

Lamplighter Inn & Suites at SDSU

2.5 star property
21 km from Otay Mesa West
9.0 out of 10, Wonderful, (1296)
"Hotel was great for a quick stay. Friendly staff and clean rooms. "
United States
Veronica
Lamplighter Inn & Suites at SDSU
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter showing night scenes, a bar and street scenes

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach Park showing a sandy beach

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Belmont Park showing rides and a park

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Otay Mesa West Hotel Reviews

Sheraton San Diego Resort

Sheraton San Diego Resort

10/10 Excellent
"The room was clean and spacious. The staff was knowledgeable and helpful. "
JEFFREY 1-night trip
Posted 17 hours ago
Sheraton San Diego Resort

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Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighbourhood that travellers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.
What is there to do around this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.