Top 10 Hotels Near Museum of Life and Science in Raleigh for 2026

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Our top choices for Museum of Life and Science hotels

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A restaurant with a large ice dispenser, wooden paneling, and red cushioned booths.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent entrance and a landscaped front yard.

A reception area with a wooden reception desk, blue seating, a flat-screen TV, and a stone accent wall.

1. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.2 km from Museum of Life and Science

BRIAN

RM348

RM395 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a desk, a chair, a television, a mirror, and a framed picture on the wall.

A vending machine area with Pepsi and other beverage options, including a selection of juices and sodas.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

2. Red Roof Inn Durham - Duke Univ Medical Center

2.2 km from Museum of Life and Science

Luis

RM256

RM297 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A hotel room with two beds, a desk, a chair, a sofa, and a TV.

A multi-story hotel with a brick facade, large windows, and a well-lit entrance.

A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

3. Fairfield by Marriott Inn & Suites Durham

17.3 km from Museum of Life and Science

Yolanda

RM484

RM550 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor seating area with wicker furniture and a stone fire pit.

A hotel lobby with a sofa, chairs, a table, and a large window offering a view of the building.

A modern hotel lobby with seating areas, large windows, and a dining section.

A conference room with a long table, chairs, and a modern chandelier.

4. Residence Inn Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

Janet

RM569

RM644 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a reception desk, seating area, and a balcony.

A Wingate hotel with a beige facade, stone entrance, and an American flag.

A hotel room with a desk, a television, a chair, a sofa, and a window with curtains.

A hotel dining area with tables, chairs, a decorative water feature, and a large window providing natural light.

5. Wingate by Wyndham Raleigh Durham Airport RTP

17.3 km from Museum of Life and Science

Supratik

RM378

RM429 total

includes taxes & fees

7 Oct - 8 Oct

A lobby with a bar area, seating, and a wine display.

A bar area with seating, a bar counter, and a menu board.

A spacious lounge with leather sofas, a long dining table, and a waterfall mural.

A covered outdoor dining area with tables set for a meal, surrounded by chairs, and overlooking a garden with blooming trees.

6. DoubleTree Raleigh Durham Airport at Research Triangle Park

16.9 km from Museum of Life and Science

Xueqin

RM465

RM528 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with high ceilings, a central fountain, and seating areas.

A spacious lobby with a curved seating area, large windows, and a modern chandelier.

An outdoor patio area with wicker furniture, stone pillars, and string lights.

A bar area with multiple liquor cabinets and hanging pendant lights.

7. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

17.5 km from Museum of Life and Science

Darren C.

RM649

RM735 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

8. Hyatt House Raleigh / RDU / Brier Creek

17.1 km from Museum of Life and Science

Alejandro

RM449

RM509 total

includes taxes & fees

1 Nov - 2 Nov

A restaurant with a bar area, yellow chairs, and tables set for dining.

An outdoor patio with hexagonal tile flooring, covered by a metal roof, and furnished with tables and chairs.

A hotel room with a bed, desk, chair, and a view of trees through the window.

A well-stocked kitchen area with various food items, beverages, and a wine rack.

9. Hilton Garden Inn Raleigh-Durham/Research Triangle Park

15.8 km from Museum of Life and Science

David

RM426

RM484 total

includes taxes & fees

31 Oct - 1 Nov

A breakfast counter with various food items and a sign that reads 'TOP IT BREAKFAST'.

A modern hotel lobby with a central counter, a refrigerated display case, and a seating area with a sofa.

An outdoor seating area with a blue sofa, orange chairs, and a table.

10. Tru by Hilton Raleigh Durham Airport

19.7 km from Museum of Life and Science

Trenton

RM432

RM489 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, a blue sofa, a small table, and a window with curtains.

A compact room with a blue sofa, a small wooden table, a microwave, a coffee maker, and a cabinet.

A kitchenette with a coffee maker, a microwave, and a small refrigerator.

A gym with cardio machines, dumbbells, a bench, and a red exercise ball.

11. Holiday Inn Express & Suites Raleigh Durham Airport at RTP by IHG

16.3 km from Museum of Life and Science

Franklin

RM530

RM602 total

includes taxes & fees

30 Oct - 31 Oct

A modern living room with a fireplace, comfortable seating, and a large window with curtains.

A courtyard with a pathway leading to a building with large windows and a yellow facade.

A hotel lobby with a reception desk, a modern abstract sculpture, and a patterned floor.

A hotel reception area with a counter, coffee station, and a large window with curtains.

12. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

North Garrett Road, 9.7 km from Museum of Life and Science

Yolanda

RM342

RM388 total

includes taxes & fees

11 Oct - 12 Oct

A modern interior with a kitchen area, dining space, and seating.

A covered outdoor area with a symmetrical design, featuring a central seating area with chairs and a table, flanked by columns and potted plants.

A compact kitchen with wooden cabinets, a black microwave, and a refrigerator. There are two chairs at a small island, and a flat-screen TV on a wooden stand.

13. Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle

16.5 km from Museum of Life and Science

Andrew

RM448

RM509 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio with a stone fire pit, seating, and a covered area.

A modern dining area with wooden tables and chairs, a kitchen in the background, and a counter with stools.

A reception area with a wooden counter, a 'HELLO Morrisville' sign, a 'PINCH' sign above a snack display, and a 'Manager on Duty' sign.

A hotel room with a bed, a desk, and a chair. There is a door and a wall-mounted lamp.

14. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

19.7 km from Museum of Life and Science

Anthony

RM412

RM467 total

includes taxes & fees

4 Oct - 5 Oct

A hallway with a modern chandelier, wooden ceiling beams, and large windows.

An outdoor seating area with modern furniture, a building entrance with glass doors, and a well-maintained garden.

An indoor swimming pool with clear glass walls, a wooden ceiling, and a view of the outdoors.

A modern hotel entrance with a large sign, a covered walkway, and a parking area.

15. Aloft by Marriott Raleigh-Durham Airport Brier Creek

17 km from Museum of Life and Science

Candace

RM608

RM689 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor seating area with wicker chairs and a large umbrella, a fire feature, and a view of the interior through glass walls.

A hotel room with a large bed, a bedside table with a lamp, a TV mounted on the wall, and a window with curtains.

A kitchen with a microwave, coffee maker, and a dishwasher.

A modern kitchen with a microwave, coffee maker, and dishwasher. There is a round table with two green chairs in front.

16. DoubleTree Suites by Hilton Raleigh - Durham

13.3 km from Museum of Life and Science

Stephen

RM395

RM448 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with wooden ceiling beams, a central bar area, multiple seating options including sofas and chairs, and framed pictures on the walls.

A Hampton Inn Suites hotel with a stone facade, large entrance doors, and a welcoming sign.

A hotel room with two beds, a headboard, bedside lamps, a television, and a window with curtains.

A spacious lobby with a reception desk, comfortable seating, and a large window.

17. Hampton Inn & Suites Chapel Hill/Durham, Area

15.2 km from Museum of Life and Science

Laura

RM465

RM528 total

includes taxes & fees

1 Nov - 2 Nov

A dining area with wooden chairs and a table, a kitchen with a red wall and a clock, and a wall-mounted artwork of the U.S. map.

A kitchen area with waffle makers, a coffee machine, and a sign indicating breakfast time.

A hotel room with a bed, bedside tables, a chair, and a desk.

A large, red sign with 'EconoLodge' written on it, set against a backdrop of lush greenery and a clear blue sky.

18. Econo Lodge Research Triangle Park

13.4 km from Museum of Life and Science

Stanley

RM215

RM244 total

includes taxes & fees

1 Nov - 2 Nov

A modern lobby with a sectional sofa, a round coffee table, and a fireplace.

A conference room with a large table and chairs, a plant, and abstract wall art.

An indoor swimming pool with clear water, surrounded by seating areas and potted plants.

A fitness center with treadmills, exercise bikes, and a weight bench.

19. Fairfield Inn & Suites Raleigh Durham Airport/ Brier Creek

17.2 km from Museum of Life and Science

Michael

RM510

RM578 total

includes taxes & fees

11 Oct - 12 Oct

A building with a prominent clock tower, a gated entrance, and a parking area with several cars.

A modern hotel lobby with a staircase, seating area, and artwork on the walls.

A reception area with a dark wood reception desk, a green wall with white leaf patterns, and a tiled floor.

A hotel breakfast area with a counter, coffee machines, and seating.

20. Sleep Inn Raleigh Durham Airport

17.2 km from Museum of Life and Science

Dwight

RM296

RM336 total

includes taxes & fees

29 Oct - 30 Oct

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Compare popular hotels close to Museum of Life and Science

Property	Property class	Guest rating
Comfort Inn & Suites Durham near Duke University	8.6 Excellent 1,159 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,001 reviews	View
Fairfield by Marriott Inn & Suites Durham	9.6 Exceptional 53 reviews	View
Residence Inn Raleigh-Durham Airport/Brier Creek	9.2 Wonderful 647 reviews	View
Wingate by Wyndham Raleigh Durham Airport RTP	8.4 Very good 1,767 reviews	View

Top Museum of Life and Science Hotel Reviews

Hilton Garden Inn Durham/University Medical Center

10/10 Excellent

"Excellent option for a hotel close to Duke Medical Center. Perfect for a short stay if traveling through Raleigh/Durham, visiting the area for work, or going to Duke Medical Hospital for any reason. About 5 minutes away from Duke Medical Center. Serves breakfast and has a lounge. Excellent dining nearby, like Parizade and JuJu -- look them up, you will not be disappointed. Updated and recently designed rooms. Fresh, consistent, always a reliable option for any discerning traveler. It's not the Ritz, but it's certainly not a low-end option. I'd choose this for a family, when traveling alone, or when traveling with a small pet. Safe. Quiet. Convenient. Clean. Nice."

21c Museum Hotel Durham

10/10 Excellent

"Truly enjoyed this hotel. Located downtown in the heart of everything. It was very clean. Totally loved the museum and bank vault. Staff were amazing as well. Room was spotless."

Hampton Inn & Suites Durham/North I-85

10/10 Excellent

"This hotel is immaculately clean, very quiet and conveniently located, and the hotel staff is so friendly and accommodating. The full breakfast in the lobby is delicious and coffee, tea, and hot chocolate are always available in the lobby."

The Durham Hotel

10/10 Excellent

"Durham is not my idea of a sought after destination but i was pleasantly surprised on a recent business trip. This Hotel is really wonderful on several levels. Firstly it’s location in downtown. Durham is fabulous and close to restaurants, coffee places, etc. all within walking distance. The front desk staff in the lobby are extremely helpful, friendly, and knowledgeable. The rooms are done with modern decor, and there is a slight art deco influence. There is ample parking at lots and garages, including city street parking right next to or adjacent to the hotel. In addition, the restaurant in the hotel itself in the lobby has excellent food at reasonable prices and a fabulous breakfast with complementary coffee for hotel guests. There were a couple of irregularities in the room, which I discussed with the front desk, which were minor. Overall, this is a four star Hotel and very reasonable priced . I highly recommend it and I would return gladly if my travels take me again to Durham NC . One word of caution having nothing to do with the hotel itself. That location downtown one must be somewhat careful and attentive . While not what I would perceive as unsafe, there are occasional homeless people who will ask for change as you’re walking along the sidewalks in the area, but not unlike many major cities in the US."

Unscripted Durham, Part of JDV by Hyatt

10/10 Excellent

"I will stay here again—it’s so centrally located, walking distance to tons of shops, restaurants, cafes, and small businesses. Everyone was so friendly and it was easy to come and go. My room was very clean. I travel a lot, and was delighted to find soft beds and towels. Really fun spot."

The Lodge at Duke Medical Center

10/10 Excellent

"My stay was great!"

Residence Inn Durham McPherson/Duke University Medical Cntr

10/10 Excellent

"Staff was friendly and helpful. Breakfast was great."

Holiday Inn Express Durham by IHG

10/10 Excellent

"clean"

Other attractions near Museum of Life and Science

Brightleaf Square

9.6/10 (8 reviews)

You can do some window-shopping at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.

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Vietnam Veterans Living Memorial

You can find out about the history of Durham with a trip to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area.

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Northgate Mall

8.2/10 (60 reviews)

You can search for that perfect souvenir at Northgate Mall during your stay in Durham. Experience the lively festivals or attend a sporting event in this family-friendly area.

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Duke Homestead

Learn about the local history of Durham when you take a trip to Duke Homestead. Attend a sporting event or visit the stunning cathedral in this family-friendly area.

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Fullsteam Brewery

7.4/10 (3 reviews)

You can take time to visit Fullsteam Brewery during your travels to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area.

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Durham Convention Center

8.2/10 (118 reviews)

Learn about the events happening in Durham Convention Center during your trip to Durham. Discover the entertainment choices and stunning cathedral in this family-friendly area.

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African American Dance Ensemble

8.8/10 (3 reviews)

You can enjoy some culture when you stop by African American Dance Ensemble in Durham.

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Carolina Theatre

8.2/10 (220 reviews)

You can get tickets for a performance at Carolina Theatre during your stay in Durham. Experience the area's entertainment choices or attend a sporting event.

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Frequently asked questions

What's the area like around Museum of Life and Science?

Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, take a look at the 10 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near Museum of Life and Science?

Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find close to Museum of Life and Science?

Expedia has 10 hotels and other accommodation options within a mile from Museum of Life and Science.

If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Museum of Life and Science.

What can I see and do near Museum of Life and Science?

You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium and Wallace Wade Stadium. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Hotels near Museum of Life and Science

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Treat yourself

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Our top choices for Museum of Life and Science hotels

1. Comfort Inn & Suites Durham near Duke University

2. Red Roof Inn Durham - Duke Univ Medical Center

3. Fairfield by Marriott Inn & Suites Durham

4. Residence Inn Raleigh-Durham Airport/Brier Creek

5. Wingate by Wyndham Raleigh Durham Airport RTP

6. DoubleTree Raleigh Durham Airport at Research Triangle Park

7. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

8. Hyatt House Raleigh / RDU / Brier Creek

9. Hilton Garden Inn Raleigh-Durham/Research Triangle Park

10. Tru by Hilton Raleigh Durham Airport

11. Holiday Inn Express & Suites Raleigh Durham Airport at RTP by IHG

12. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

13. Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle

14. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

15. Aloft by Marriott Raleigh-Durham Airport Brier Creek

16. DoubleTree Suites by Hilton Raleigh - Durham

17. Hampton Inn & Suites Chapel Hill/Durham, Area

18. Econo Lodge Research Triangle Park

19. Fairfield Inn & Suites Raleigh Durham Airport/ Brier Creek

20. Sleep Inn Raleigh Durham Airport

Compare popular hotels close to Museum of Life and Science

Top Museum of Life and Science Hotel Reviews

Hilton Garden Inn Durham/University Medical Center

21c Museum Hotel Durham

Hampton Inn & Suites Durham/North I-85

The Durham Hotel

Unscripted Durham, Part of JDV by Hyatt

The Lodge at Duke Medical Center

Residence Inn Durham McPherson/Duke University Medical Cntr

Holiday Inn Express Durham by IHG

Other attractions near Museum of Life and Science

Brightleaf Square

Vietnam Veterans Living Memorial

Northgate Mall

Duke Homestead

Fullsteam Brewery

Durham Convention Center

African American Dance Ensemble

Carolina Theatre

Frequently asked questions